Spliced leader RNA of trypanosomes: in vivo mutational analysis reveals extensive and distinct requirements for trans splicing and cap4 formation. (Q41076745)

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English	Spliced leader RNA of trypanosomes: in vivo mutational analysis reveals extensive and distinct requirements for trans splicing and cap4 formation.	scientific article

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20 October 2019

Spliced leader RNA of trypanosomes: in vivo mutational analysis reveals extensive and distinct requirements for trans splicing and cap4 formation (English)

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20 October 2019

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mutational analysis

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S Lücke

1

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20 October 2019

G L Xu

2

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20 October 2019

Z Palfi

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20 October 2019

M Cross

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20 October 2019

V Bellofatto

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20 October 2019

A Bindereif

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20 October 2019

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1 August 1996

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20 October 2019

The EMBO Journal

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20 October 2019

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20 October 2019

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20 October 2019

4380-4391

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20 October 2019

Autonomously replicating single-copy episomes in Trypanosoma brucei show unusual stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

The Leptomonas collosoma spliced leader RNA can switch between two alternate structural forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Trans-splicing of nematode premessenger RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Functional analysis of cis-acting DNA elements required for expression of the SL RNA gene in the parasitic protozoan Leishmania amazonensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

A conserved upstream element is essential for transcription of the Leishmania tarentolae mini-exon gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

In vivo structural analysis of spliced leader RNAs in Trypanosoma brucei and Leptomonas collosoma: a flexible structure that is independent of cap4 methylations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Controlled turnover and 3' trimming of the trans splicing precursor of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Discontinuous transcription in Leptomonas seymouri: presence of intact and interrupted mini-exon gene families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Characterization of RNA transcripts from the alpha tubulin gene cluster of Leptomonas seymouri

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Trypanosome mRNAs have unusual "cap 4" structures acquired by addition of a spliced leader

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Isolation and sequence of four small nuclear U RNA genes of Trypanosoma brucei subsp. brucei: identification of the U2, U4, and U6 RNA analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Direct analysis of the mini-exon donor RNA of Trypanosoma brucei: detection of a novel cap structure also present in messenger RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Spliced leader RNA sequences can substitute for the essential 5' end of U1 RNA during splicing in a mammalian in vitro system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

The nematode spliced leader RNA participates in trans-splicing as an Sm snRNP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Unexpected flexibility in an evolutionarily conserved protein-RNA interaction: genetic analysis of the Sm binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Trans splicing of nuclear pre-mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Intramolecular base pairing between the nematode spliced leader and its 5' splice site is not essential for trans-splicing in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Affinity purification of Trypanosoma brucei small nuclear ribonucleoproteins reveals common and specific protein components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Trans splicing in trypanosomes requires methylation of the 5' end of the spliced leader RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Stable transformation of Leptomonas seymouri by circular extrachromosomal elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Analysis of small nuclear ribonucleoproteins (RNPs) in Trypanosoma brucei: structural organization and protein components of the spliced leader RNP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Trypanosoma brucei spliced-leader RNA methylations are required for trans splicing in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Three novel functional variants of human U5 small nuclear RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Domain Structure of U2 and U4/U6 Small Nuclear Ribonucleoprotein Particles from Trypanosoma brucei: Identification of trans-Spliceosomal Specific RNA-Protein Interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Transcription of a nematode trans-spliced leader RNA requires internal elements for both initiation and 3' end-formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

26 September 2017

Leptomonas seymouri as a model system for the analysis of gene expression in trypanosomatids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Mutations in U6 snRNA that alter splice site specificity: implications for the active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

trans-spliceosomal U6 RNAs of Crithidia fasciculata and Leptomonas seymouri: deviation from the conserved ACAGAG sequence and potential base pairing with spliced leader RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Trans splicing involves a novel form of small nuclear ribonucleoprotein particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Discontinuously synthesized mRNA from Trypanosoma brucei contains the highly methylated 5' cap structure, m7GpppA*A*C(2'-O)mU*A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Characterization of the spliced leader genes and transcripts in Trypanosoma cruzi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Expression of a bacterial gene in a trypanosomatid protozoan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Trans splicing of nematode pre-messenger RNA in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Isolation of distinct small ribonucleoprotein particles containing the spliced leader and U2 RNAs of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Interaction of U6 snRNA with a sequence required for function of the nematode SL RNA in trans-splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Immunological characterization and intracellular localization of trans-spliceosomal small nuclear ribonucleoproteins in Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Mass spectrometry of mRNA cap 4 from trypanosomatids reveals two novel nucleosides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

14 June 2018

Spliced leader-associated RNA of trypanosomes. Sequence conservation and association with protein components common to trans-spliceosomal ribonucleoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

19 August 2018

An early hierarchic role of U1 small nuclear ribonucleoprotein in spliceosome assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452162

19 August 2018

An episome of Trypanosoma brucei can exist as an extrachromosomal element in a broad range of trypanosomatids but shows different requirements for stable replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential components of the mini-exon gene promoter in the trypanosomatid Leptomonas seymouri

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isotopes incorporated in the Nucleic Acids of Trypanosoma mega

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: evidence for trans splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for trans splicing in trypanosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trans splicing: variation on a familiar theme?

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Destruction of U2, U4, or U6 small nuclear RNA blocks trans splicing in trypanosome cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Splicing takes a holliday

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of U6 snRNA in 5' splice site selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/8861965

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1996.TB00811.X

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8861965%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8861965%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8861965%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

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