Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B. (Q41079207)

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7 November 2019

title

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B (English)

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7 November 2019

4

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7 November 2019

Stephen G Ward

6

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7 November 2019

5

Hemmings BA

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7 November 2019

author name string

Parry RV

1

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7 November 2019

Reif K

2

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7 November 2019

Smith G

3

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7 November 2019

language of work or name

English

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publication date

1 October 1997

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European Journal of Immunology

7 November 2019

published in

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7 November 2019

volume

27

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7 November 2019

issue

10

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7 November 2019

page(s)

2495-2501

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CD28: a signalling perspective.

7 November 2019

cites work

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

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Involvement of phosphatidylinositol 3-kinase in the activation of p70 S6 kinase by the T cell costimulatory molecule CD28.

21 January 2018

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

21 January 2018

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Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

21 January 2018

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The B7 and CD28 receptor families

21 January 2018

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7 January 2021

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

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7 January 2021

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

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7 January 2021

Both CD28 ligands CD80 (B7-1) and CD86 (B7-2) activate phosphatidylinositol 3-kinase, and wortmannin reveals heterogeneity in the regulation of T cell IL-2 secretion.

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7 January 2021

PI 3-kinase: a pivotal pathway in T-cell activation?

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7 January 2021

Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

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7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

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7 January 2021

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation

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7 January 2021

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

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7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

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7 January 2021

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

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7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

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7 January 2021

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

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7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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7 January 2021

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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7 January 2021

Akt signaling: linking membrane events to life and death decisions

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7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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7 January 2021

Cross-linking CD28 leads to activation of 70-kDa S6 kinase

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271006

7 January 2021

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271006

7 January 2021

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271006

7 January 2021

A role in transmembrane signaling for the cytoplasmic domain of the CD2 T lymphocyte surface antigen

1 reference

https://api.crossref.org/works/10.1002%2FEJI.1830271006

7 January 2021

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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7 January 2021

Nuclear localization of p85s6k: functional requirement for entry into S phase.

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7 January 2021

p70s6k function is essential for G1 progression

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7 January 2021

Identifiers

DOI

10.1002/EJI.1830271006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9368602%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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