FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b. (Q41085784)

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6 November 2019

title

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b (English)

1 reference

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6 November 2019

4

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6 November 2019

author name string

C Scaffidi

series ordinal

1

1 reference

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6 November 2019

J P Medema

series ordinal

2

1 reference

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6 November 2019

P H Krammer

series ordinal

3

1 reference

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6 November 2019

language of work or name

English

0 references

publication date

1 October 1997

1 reference

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Journal of Biological Chemistry

6 November 2019

published in

1 reference

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6 November 2019

volume

272

1 reference

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6 November 2019

issue

43

1 reference

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6 November 2019

page(s)

26953-26958

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Social controls on cell survival and cell death

6 November 2019

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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ICE family proteases: mediators of all apoptotic cell death?

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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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Molecular cloning of the interleukin-1 beta converting enzyme

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A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

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Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

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Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

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Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases

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Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases

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Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme

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ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

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Identification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32

21 January 2018

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ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

21 January 2018

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The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32

21 January 2018

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Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling

21 January 2018

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Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

21 January 2018

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21 January 2018

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Cloning and expression of four novel isoforms of human interleukin-1 beta converting enzyme with different apoptotic activities

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