Prostaglandin endoperoxide H synthases-1 and -2. (Q41090404)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8781269%20AND%20SRC:MED&resulttype=core&format=json

18 October 2019

review article

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title

Prostaglandin endoperoxide H synthases-1 and -2 (English)

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18 October 2019

author name string

Smith WL

series ordinal

1

1 reference

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18 October 2019

Dewitt DL

series ordinal

2

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18 October 2019

publication date

1 January 1996

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18 October 2019

published in

Advances in Immunology

1 reference

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18 October 2019

volume

62

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18 October 2019

page(s)

167-215

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Interleukin-1-Induced Prostaglandin E2 Biosynthesis in Human Synovial Cells Involves the Activation of Cytosolic Phospholipase A2 and Cyclooxygenase-2

18 October 2019

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Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta

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Higher oxidation states of prostaglandin H synthase. Rapid electronic spectroscopy detected two spectral intermediates during the peroxidase reaction with prostaglandin G2

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Prostaglandin H synthase and xenobiotic oxidation

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Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression

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NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions

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NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

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Apical-basolateral membrane asymmetry in canine cortical collecting tubule cells. Bradykinin, arginine vasopressin, prostaglandin E2 interrelationships

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Regulation of prostaglandin H synthase 2 expression in human monocytes by the marine natural products manoalide and scalaradial. Novel effects independent of inhibition of lipid mediator production

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Effect of prostaglandin E1 on the permeability response of the isolated collecting tubule to vasopressin, adenosine 3',5'-monophosphate, and theophylline

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C/EBP, NF-kappa B, and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1 alpha immediate-early gene

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Human platelet-derived growth factor stimulates prostaglandin synthesis by activation and by rapid de novo synthesis of cyclooxygenase

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Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts

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Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction

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7 January 2021

Nonsteroidal antiinflammatory drugs and human cancer. Report of an interdisciplinary research workshop

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Prostaglandin endoperoxide synthase in rat ovarian follicles: content, cellular distribution, and evidence for hormonal induction preceding ovulation

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Interleukin-1 beta induces cytosolic phospholipase A2 and prostaglandin H synthase in rheumatoid synovial fibroblasts. Evidence for their roles in the production of prostaglandin E2.

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Higher oxidation states of prostaglandin H synthase. EPR study of a transient tyrosyl radical in the enzyme during the peroxidase reaction

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7 January 2021

Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2

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7 January 2021

Prostaglandin endoperoxide synthase gene structure: identification of the transcriptional start site and 5'-flanking regulatory sequences

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7 January 2021

Requirements for hydroperoxide by the cyclooxygenase and peroxidase activities of prostaglandin H synthase

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7 January 2021

Comparison of hydroperoxide initiator requirements for the cyclooxygenase activities of prostaglandin H synthase-1 and -2.

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7 January 2021

Prostaglandin H synthase: spectroscopic studies of the interaction with hydroperoxides and with indomethacin

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7 January 2021

Enzymatic conversions of 10,10-difluoroarachidonic acid with PGH synthase and soybean lipoxygenase

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Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid

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Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

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Mutation of serine-516 in human prostaglandin G/H synthase-2 to methionine or aspirin acetylation of this residue stimulates 15-R-HETE synthesis

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Selective Induction of Prostaglandin G/H Synthase I by Stem Cell Factor and Dexamethasone in Mast Cells

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7 January 2021

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7 January 2021

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New Alzheimer's therapy suggested.

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The oxidation of arachidonic acid by the cyclooxygenase activity of purified prostaglandin H synthase: spin trapping of a carbon-centered free radical intermediate

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7 January 2021

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

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7 January 2021

Identification of a phorbol ester-repressible v-src-inducible gene

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7 January 2021

Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1).

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7 January 2021

Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular gland

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7 January 2021

Lack of covalent modification of prostaglandin synthetase (cyclo-oxygenase) by indomethacin

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7 January 2021

Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene

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Aspirin use and reduced risk of fatal colon cancer

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7 January 2021

Prostaglandin endoperoxide synthase contains an EGF-like domain

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7 January 2021

Human peritoneal mesothelial cell prostaglandin synthesis: induction of cyclooxygenase mRNA by peritoneal macrophage-derived cytokines

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7 January 2021

Interaction between nitric oxide and prostaglandin H synthase

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7 January 2021

Spectroscopic evidence for reaction of prostaglandin H synthase-1 tyrosyl radical with arachidonic acid.

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7 January 2021

Purification of PGH synthase from sheep vesicular glands

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7 January 2021

Purification and characterisation of prostaglandin endoperoxide synthetase from sheep vesicular glands

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7 January 2021

Acetylation of prostaglandin endoperoxide synthetase with acetylsalicylic acid

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7 January 2021

Time-dependent inhibition of platelet cyclo-oxygenase by indomethacin is slowly reversible

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7 January 2021

Comparison of branched-chain and tightly coupled reaction mechanisms for prostaglandin H synthase

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7 January 2021

The Use of Aspirin in Ischemic Heart Disease

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7 January 2021

Rapid induction of prostaglandin endoperoxide synthase in rat preovulatory follicles by luteinizing hormone and cAMP is blocked by inhibitors of transcription and translation

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7 January 2021

v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor

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7 January 2021

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

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7 January 2021

Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

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7 January 2021

Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme

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7 January 2021

Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence.

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7 January 2021

10.1016/S0065-2776(08)60430-7

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