IFN-gamma inducibility of class II transactivator is specifically lacking in human tumour lines: relevance to retinoblastoma protein rescue of IFN-gamma inducibility of the HLA class II genes (Q41095713)

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scientific article published on August 1997

Language	Label	Description	Also known as
English	IFN-gamma inducibility of class II transactivator is specifically lacking in human tumour lines: relevance to retinoblastoma protein rescue of IFN-gamma inducibility of the HLA class II genes	scientific article published on August 1997

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 September 2017

IFN-gamma inducibility of class II transactivator is specifically lacking in human tumour lines: relevance to retinoblastoma protein rescue of IFN-gamma inducibility of the HLA class II genes (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

1 reference

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author name string

Lu Y

1

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Europe PubMed Central

PubMed publication ID

26 September 2017

Tschickardt ME

2

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26 September 2017

Schmidt BJ

3

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26 September 2017

Blanck G

4

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26 September 2017

publication date

1 August 1997

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26 September 2017

Immunology & Cell Biology

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26 September 2017

75

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Europe PubMed Central

PubMed publication ID

26 September 2017

4

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PubMed publication ID

26 September 2017

325-332

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PubMed publication ID

26 September 2017

https://scigraph.springernature.com/pub.10.1038/icb.1997.50

0 references

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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Regulatory elements and transcription factors controlling basal and cytokine-induced expression of the gene encoding intercellular adhesion molecule 1.

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Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

1 reference

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

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Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA)

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Assembly, transport, and function of MHC class II molecules

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Current concepts in DRA gene regulation

1 reference

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An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

1 reference

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Mediation by HLA-DM of dissociation of peptides from HLA-DR

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HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

1 reference

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Vitamin D3 reduces the apoptotic effect of IFN-gamma but does not facilitate HLA class II inducibility in RB-defective cells

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A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

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The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice

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Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

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MHC class II-transfected tumor cells induce long-term tumor-specific immunity in autologous mice.

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Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice

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Enhancement of anti-tumour immunity in syngeneic mice after MHC class II gene transfection

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The retinoblastoma protein as a transcriptional repressor

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Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2

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A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor

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Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

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Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction

1 reference

https://api.crossref.org/works/10.1038%2FICB.1997.50

21 January 2018

Class II transactivator regulates the expression of multiple genes involved in antigen presentation

1 reference

https://api.crossref.org/works/10.1038%2FICB.1997.50

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Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons

1 reference

https://api.crossref.org/works/10.1038%2FICB.1997.50

21 January 2018

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1 reference

https://api.crossref.org/works/10.1038%2FICB.1997.50

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High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons

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Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

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A genetic model for colorectal tumorigenesis

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Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

1 reference

https://api.crossref.org/works/10.1038%2FICB.1997.50

7 January 2021

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Synergistic activation of intercellular adhesion molecule 1 (ICAM-1) by TNF-alpha and IFN-gamma is mediated by p65/p50 and p65/c-Rel and interferon-responsive factor Stat1 alpha (p91) that can be activated by both IFN-gamma and IFN-alpha

1 reference

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Retinoblastoma protein regulation of surface CD74 (invariant chain) expression in breast carcinoma cells

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RB and A novel E2F‐1 binding protein in MHC class II deficient B‐cell lines and normal IFN‐γ induction of the class II transactivator ciita in class II non‐inducible RB‐defective tumor lines

1 reference

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Gamma-interferon induction of HLA class II mRNAs in dermal fibroblasts studied by RNAse protection analysis

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7 January 2021

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Analysis of differential HLA-DQB expression in autologous B cell lines.

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7 January 2021

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10.1038/ICB.1997.50

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 September 2017

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