Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein (Q41125447)

27 September 2017

title

Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein (English)

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27 September 2017

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Weidemann A

1

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27 September 2017

Paliga K

2

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27 September 2017

Dürrwang U

3

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27 September 2017

Czech C

4

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27 September 2017

Evin G

5

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27 September 2017

Masters CL

6

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27 September 2017

Beyreuther K

7

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27 September 2017

language of work or name

English

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publication date

1 March 1997

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27 September 2017

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27 September 2017

volume

3

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27 September 2017

issue

3

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27 September 2017

page(s)

328-332

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

27 September 2017

cites work

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Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

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Presenilins and Alzheimer disease

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The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

21 January 2018

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Amyloid beta-protein and the genetics of Alzheimer's disease

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.

21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

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Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

21 January 2018

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

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Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

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Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

21 January 2018

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Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion.

21 January 2018

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Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus

21 January 2018

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Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

21 January 2018

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The Alzheimer beta-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells

21 January 2018

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Inhibition of amyloid beta-protein production in neural cells by the serine protease inhibitor AEBSF.

21 January 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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Generation of beta A4 from the amyloid protein precursor and fragments thereof

21 January 2018

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Candidate gene for the chromosome 1 familial Alzheimer's disease locus

21 January 2018

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7 January 2021

Cleavage of amyloid beta peptide during constitutive processing of its precursor

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7 January 2021

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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7 January 2021

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

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https://api.crossref.org/works/10.1038%2FNM0397-328

7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

1 reference

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7 January 2021

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

1 reference

https://api.crossref.org/works/10.1038%2FNM0397-328

7 January 2021

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1038%2FNM0397-328

7 January 2021

Identifiers

DOI

10.1038/NM0397-328

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Dimensions Publication ID

27 September 2017

1045664611

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