Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole (Q41128197)

27 September 2017

1 reference

title

Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole (English)

1 reference

27 September 2017

1 reference

1 reference

T Andersson

1

1 reference

PubMed ID

8827397

27 September 2017

language of work or name

1 reference

1 July 1996

1 reference

Clinical Pharmacokinetics

27 September 2017

1 reference

27 September 2017

31

1 reference

27 September 2017

1

1 reference

27 September 2017

9-28

1 reference

https://scigraph.springernature.com/pub.10.2165/00003088-199631010-00002

27 September 2017

0 references

cites work

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test

1 reference

12 December 2020

Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes

1 reference

12 December 2020

Genetically determined variability in acetylation and oxidation. Therapeutic implications

1 reference

12 December 2020

Lansoprazole and omeprazole have similar effects on plasma gastrin levels, enterochromaffin-like cells, gastrin cells and somatostatin cells in the rat stomach

1 reference

12 December 2020

Correlation of human cytochrome P4502C substrate specificities with primary structure: warfarin as a probe

1 reference

12 December 2020

Cytochrome P450: evolution and functional diversity.

1 reference

12 December 2020

Pharmacokinetics of omeprazole in cirrhotic patients

1 reference

12 December 2020

Increase of cytochrome P450IA2 activity by omeprazole: evidence by the 13C-[N-3-methyl]-caffeine breath test in poor and extensive metabolizers of S-mephenytoin

1 reference

12 December 2020

Effects of ranitidine and sucralfate on ketoconazole bioavailability

1 reference

12 December 2020

Oxidative metabolism of omeprazole in human liver microsomes: cosegregation with S-mephenytoin 4'-hydroxylation

1 reference

12 December 2020

Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism

1 reference

12 December 2020

Effect of single dose of omeprazole on the gastrointestinal peptide response to food

1 reference

12 December 2020

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

1 reference

12 December 2020

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

1 reference

12 December 2020

Renal function in an elderly population. A study of S-creatinine, 51Cr-EDTA clearance, endogenous creatinine clearance and maximal tubular water reabsorption

1 reference

12 December 2020

Relation between chloroguanide bioactivation to cycloguanil and the genetically determined metabolism of mephenytoin in humans

1 reference

12 December 2020

The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction

1 reference

12 December 2020

Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies

1 reference

12 December 2020

Lack of effect of antacids on plasma concentrations of omeprazole given as enteric-coated granules

1 reference

12 December 2020

No influence of single intravenous doses of omeprazole on theophylline elimination kinetics

1 reference

12 December 2020

Omeprazole treatment does not affect the metabolism of caffeine

1 reference

12 December 2020

Review article: the continuing development of proton pump inhibitors with particular reference to pantoprazole

1 reference

12 December 2020

In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase

1 reference

12 December 2020

Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism

1 reference

12 December 2020

Oxidative metabolism of lansoprazole by human liver cytochromes P450.

1 reference

12 December 2020

Omeprazole in elderly duodenal ulcer patients: relationship between reduction in gastric acid secretion and fasting plasma gastrin.

1 reference

12 December 2020

The effect of oral omeprazole on the disposition of lignocaine.

1 reference

12 December 2020

Slow omeprazole metabolizers are also poor S-mephenytoin hydroxylators.

1 reference

12 December 2020

Omeprazole drug interaction studies

1 reference

12 December 2020

Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation

1 reference

12 December 2020

Development of an oral formulation of omeprazole.

1 reference

12 December 2020

Pharmacokinetics--a relevant factor for the choice of a drug?

1 reference

12 December 2020

Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6

1 reference

12 December 2020

Effect of pantoprazole on 24-h intragastric pH and serum gastrin in humans.

1 reference

12 December 2020

Pharmacokinetic study of omeprazole in elderly healthy volunteers

1 reference

12 December 2020

Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.

1 reference

12 December 2020

Minor effect of multiple dose omeprazole on the pharmacokinetics of digoxin after a single oral dose

1 reference

12 December 2020

Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef

1 reference

12 December 2020

Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies

1 reference

12 December 2020

Lack of pantoprazole drug interactions in man.

1 reference

12 December 2020

Effect of cigarette smoking on phenacetin metabolism

1 reference

12 December 2020

Evidence that CYP2C19 is the major (S)-mephenytoin 4'-hydroxylase in humans

1 reference

12 December 2020

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

1 reference

12 December 2020

Influence of single- and multiple-dose omeprazole treatment on nifedipine pharmacokinetics and effects in healthy subjects

1 reference

12 December 2020

Lack of effect of omeprazole treatment on steady-state plasma levels of metoprolol

1 reference

12 December 2020

Lansoprazole does not affect the bioavailability of oral contraceptives

1 reference

12 December 2020

Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole.

1 reference

12 December 2020

Selective expression of cytochrome P450 CYP3A mRNAs in embryonic and adult human liver

1 reference

12 December 2020

Oral phenytoin pharmacokinetics during omeprazole therapy

1 reference

12 December 2020

Pharmacokinetics of [14C]omeprazole in patients with impaired renal function

1 reference

12 December 2020

Lack of effect of pantoprazole on the pharmacodynamics and pharmacokinetics of warfarin

1 reference

12 December 2020

In vivo and in vitro studies of the site of inhibitory action of omeprazole on adrenocortical steroidogenesis

1 reference

12 December 2020

Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase

1 reference

12 December 2020

Hepatic microsomal tolbutamide hydroxylation in Japanese: in vitro evidence for rapid and slow metabolizers

1 reference

12 December 2020

Effects of omeprazole and lansoprazole on 24-hour intragastric pH in Helicobacter pylori-positive volunteers

1 reference

12 December 2020

Inhibition by omeprazole of adrenocortical response to ACTH: clinical studies and experiments on bovine adrenal cortex in vitro

1 reference

12 December 2020

Continuing development of acid pump inhibitors: site of action of pantoprazole.

1 reference

12 December 2020

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine

1 reference

12 December 2020

1 reference

12 December 2020

Omeprazole and the induction of human cytochrome P-450: a response to concerns about potential adverse effects

1 reference

12 December 2020

Hypothalamic-Pituitary-Gonadal Dysfunction in Men Using Cimetidine

1 reference

12 December 2020

Relationships between the levels of cytochrome P4502C9 and its prototypic catalytic activities in human liver microsomes

1 reference

12 December 2020

Influence of lansoprazole treatment on diazepam plasma concentrations

1 reference

12 December 2020

Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities

1 reference

12 December 2020

Age, environmental factors and drug metabolism

1 reference

12 December 2020

Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation

1 reference

12 December 2020

Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes

1 reference

12 December 2020

Polymorphic hydroxylation of S-mephenytoin and omeprazole metabolism in Caucasian and Chinese subjects

1 reference

12 December 2020

Inhibition by etomidate of steroidogenesis in isolated bovine adrenal cells

1 reference

12 December 2020

Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man

1 reference

12 December 2020

A study of the interaction between omeprazole and phenytoin in epileptic patients

1 reference

12 December 2020

A study of the interaction between omeprazole and cyclosporine in renal transplant patients

1 reference

12 December 2020

Lack of effect of omeprazole, cimetidine, and ranitidine on the pharmacokinetics of ethanol in fasting male volunteers.

1 reference

12 December 2020

Lack of influence of pantoprazole on the disposition kinetics of theophylline in man.

1 reference

12 December 2020

A dose-effect study of the in vivo inhibitory effect of quinidine on sparteine oxidation in man.

1 reference

12 December 2020

Pharmacokinetics of lansoprazole in patients with renal or liver disease of varying severity

1 reference

12 December 2020

The effects of omeprazole on endocrine function in man.

1 reference

12 December 2020

Drugs other than H2-receptor antagonists as clinically important inhibitors of drug metabolism in vivo

1 reference

12 December 2020

Effect of omeprazole--a gastric proton pump inhibitor--on pentagastrin stimulated acid secretion in man

1 reference

12 December 2020

Differences in the cytochrome P-450 isoenzymes involved in the 2-hydroxylation of oestradiol and 17 alpha-ethinyloestradiol. Relative activities of rat and human liver enzymes

1 reference

12 December 2020

Ketoconazole Blocks Adrenal Steroid Synthesis

1 reference

12 December 2020

Disposition kinetics and metabolism of omeprazole in extensive and poor metabolizers of S-mephenytoin 4'-hydroxylation recruited from an Oriental population.

1 reference

12 December 2020

The interaction of proton pump inhibitors with cytochromes P450.

1 reference

12 December 2020

Omeprazole does not enhance the metabolism of phenacetin, a marker of CYP1A2 activity, in healthy volunteers

1 reference

12 December 2020

Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4.

1 reference

12 December 2020

Antisecretory effect and oral pharmacokinetics of omeprazole in patients with chronic renal failure

1 reference

12 December 2020

Propranolol steady-state pharmacokinetics are unaltered by omeprazole

1 reference

12 December 2020

Oxidation of quinidine by human liver cytochrome P-450

1 reference

12 December 2020

The mechanism of action of the gastric acid secretion inhibitor omeprazole

1 reference

12 December 2020

Hepatic drug clearance: the effect of age using indocyanine green as a model compound

1 reference

12 December 2020

Theophylline steady state pharmacokinetics is not altered by omeprazole

1 reference

12 December 2020

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature

1 reference

12 December 2020

Comparison of levels of several human microsomal cytochrome P-450 enzymes and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples

1 reference

12 December 2020

Pharmacokinetics of [14C]omeprazole in patients with liver cirrhosis

1 reference

12 December 2020

Effects of pantoprazole on endocrine function in healthy male volunteers

1 reference

12 December 2020

1 reference

12 December 2020

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

1 reference

12 December 2020

Pharmacokinetics and metabolism of omeprazole in animals and man--an overview

1 reference

12 December 2020

Twenty-four-hour intragastric acidity and plasma gastrin concentration before and during treatment with either ranitidine or omeprazole

1 reference

12 December 2020

A study of the interaction of omeprazole and warfarin in anticoagulated patients

1 reference

12 December 2020

Stereoselective interaction of omeprazole with warfarin in healthy men

1 reference

12 December 2020

Effect of omeprazole and cimetidine on plasma diazepam levels.

1 reference

12 December 2020

Assessment of liver metabolic function. Clinical implications

1 reference

12 December 2020

Defective metabolism of metoprolol in poor hydroxylators of debrisoquine

1 reference

12 December 2020

Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+ + K+) ATPase

1 reference

12 December 2020

Histamine H1- and H2-receptors in the gastrointestinal circulation

1 reference

12 December 2020

Influence of gastric acidity on the bioavailability of digoxin

1 reference

12 December 2020

Bioavailability studies on a buffered acetylsalicylic acid preparation

1 reference

12 December 2020

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

1 reference

12 December 2020

The effects of lansoprazole, 30 or 60 mg daily, on intragastric pH and on endocrine function in healthy volunteers

1 reference

12 December 2020

Absence of an inhibitory effect of omeprazole and nizatidine on phenytoin disposition, a marker of CYP2C activity

1 reference

12 December 2020

No influence of pantoprazole on the pharmacokinetics of phenytoin

1 reference

12 December 2020

Histamine H1- and H2-receptor vasodilation of canine intestinal circulation

1 reference

12 December 2020

Single and multiple dose pharmacokinetics of lansoprazole in elderly subjects

1 reference

12 December 2020

Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs.

1 reference

12 December 2020

Characterization of human liver cytochromes P-450 involved in theophylline metabolism

1 reference

12 December 2020

No effect of omeprazole-induced hypoacidity on the bioavailability of amoxycillin or bacampicillin

1 reference

12 December 2020

Omeprazole fails to alter the cytochrome P450-dependent 2-hydroxylation of estradiol in male volunteers

1 reference

12 December 2020

1 reference

12 December 2020

The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans

1 reference

12 December 2020

Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro.

1 reference

12 December 2020

Interethnic differences in omeprazole metabolism in the two S-mephenytoin hydroxylation phenotypes studied in Caucasians and Orientals

1 reference

12 December 2020

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1 reference

12 December 2020

Quinidine single dose pharmacokinetics and pharmacodynamics are unaltered by omeprazole

1 reference

12 December 2020

Specific and dose-dependent enzyme induction by omeprazole in human beings.

1 reference

12 December 2020

Co-regulation of phenytoin and tolbutamide metabolism in humans

1 reference

12 December 2020

The anti-secretory effect and pharmacokinetics of omeprazole in chronic liver disease

1 reference

12 December 2020

The effect of food and antacids on lansoprazole absorption and disposition

1 reference

12 December 2020

Safety of lansoprazole.

1 reference

12 December 2020

The pharmacokinetics of omeprazole in humans--a study of single intravenous and oral doses

1 reference

12 December 2020

10.2165/00003088-199631010-00002

Identifiers

DOI

1 reference

PubMed ID

8827397

Dimensions Publication ID

27 September 2017

0 references

1 reference

PubMed ID

8827397