Topical glucocorticoids with improved risk-benefit ratio. Rationale of a new concept (Q41128727)

27 September 2017

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title

Topical glucocorticoids with improved risk-benefit ratio. Rationale of a new concept (English)

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27 September 2017

M Schäfer-Korting

1

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27 September 2017

M H Schmid

series ordinal

2

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27 September 2017

H C Korting

series ordinal

3

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27 September 2017

publication date

1 June 1996

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27 September 2017

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27 September 2017

volume

14

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27 September 2017

issue

6

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27 September 2017

page(s)

375-385

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Cytokine inhibition by a novel steroid, mometasone furoate

27 September 2017

cites work

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12 December 2020

Binding affinities of rimexolone (ORG 6216), flunisolide and their putative metabolites for the glucocorticoid receptor of human synovial tissue

1 reference

12 December 2020

Factor-assisted DNA binding as a possible general mechanism for steroid receptors. Functional heterogeneity among activated receptor-steroid complexes

1 reference

12 December 2020

Binding affinities of mometasone furoate and related compounds including its metabolites for the glucocorticoid receptor of rat skin tissue

1 reference

12 December 2020

Biotransformation of the topical glucocorticoids budesonide and beclomethasone 17α,21-dipropionate in human liver and lung homogenate

1 reference

12 December 2020

Comparison of xeroradiographic and ultrasound detection of corticosteroid induced dermal thinning

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12 December 2020

Steroid-induced damage of the facial skin following use of prednicarbate

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12 December 2020

Discrimination of the toxic potential of chemically differing topical glucocorticoids using a neutral red release assay with human keratinocytes and fibroblasts

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12 December 2020

Enzymes and receptors: challenges and future directions

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12 December 2020

[A clinical trial of desired and unwanted effects of topically applied glucocorticosteroids in the human]

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12 December 2020

Small reduction of capsaicin-induced neurogenic inflammation in human forearm skin by the glucocorticoid prednicarbate

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12 December 2020

Two glucocorticoid binding sites on the human glucocorticoid receptor

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12 December 2020

Prednicarbate activity and benefit/risk ratio in relation to other topical glucocorticoids

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12 December 2020

Observations on the systemic effect of topical clobetasol propionate (Dermovate)

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12 December 2020

Predominant High Affinity Binding of [3H]-Dexamethasone in Bovine Tissues Is Not to Classical Glucocorticoid Receptors*

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12 December 2020

Risk-benefit analyses of drugs: fundamental considerations and requirements from the point of view of the biometrician. Problems in the assessment of the combination of trimethoprim with sulfamethoxazole

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12 December 2020

Triamcinolone acetonide: a highly effective new topical steroid

1 reference

12 December 2020

Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region

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12 December 2020

Potency Assessment of Topical Corticoids in the Vasoconstrictor Assay and on Tuberculin-Induced Inflammation

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12 December 2020

Influence of corticosteroids on chemotactic response and collagen metabolism of human skin fibroblasts

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12 December 2020

Comparative toxicity study of hydrocortisone 17-butyrate 21-propionate (HBP) ointment and other topical corticosteroids in rats

1 reference

12 December 2020

Mometasone furoate ointment 0.1% vs. hydrocortisone ointment 1.0% in psoriasis. Atrophogenic potential

1 reference

12 December 2020

Enhancement of affinity to receptors in the esterified glucocorticoid, hydrocortisone 17-butyrate 21-propionate (HBP), in the rat liver

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12 December 2020

The effect of hydrocortisone aceponate on proliferation, total protein synthesis and collagen synthesis in human skin fibroblasts in vitro

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12 December 2020

Studies on the pharmacokinetics and metabolism of prednicarbate after cutaneous and oral administration

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12 December 2020

In vivo assessment of the atrophogenic potency of mometasone furoate, a newly developed chlorinated potent topical glucocorticoid as compared to other topical glucocorticoids old and new.

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12 December 2020

Comparison of the effects of calcipotriol, prednicarbate and clobetasol 17-propionate on normal skin assessed by ultrasound measurement of skin thickness

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12 December 2020

Morning plasma cortisol levels in infants treated with topical fluorinated glucocorticosteroids

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12 December 2020

Homologous down regulation of the glucocorticoid receptor: the molecular machinery.

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12 December 2020

Influence of corticosteroids on ultraviolet light erythema and pigmentation in man

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12 December 2020

Morphometric studies of the localization of the glucocorticoid receptor in mammalian cells and of glucocorticoid hormone-induced effects

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12 December 2020

Mometasone furoate ointment and cream 0.1 percent in treatment of psoriasis: comparison with ointment and cream formulations of fluocinolone acetonide 0.025 percent and triamcinolone acetonide 0.1 percent

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12 December 2020

Activity of topically applied methylprednisolone aceponate in relation to other topical glucocorticosteroids in healthy volunteers.

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12 December 2020

Clinical evaluation of hydrocortisone valerate 0.2% ointment

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12 December 2020

Steroidal anti-inflammatory antedrugs: synthesis and pharmacological evaluation of 16 alpha-alkoxycarbonyl-17-deoxyprednisolone derivatives

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12 December 2020

Activation of beclomethasone dipropionate by hydrolysis to beclomethasone-17-monopropionate

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12 December 2020

Localization of the glucocorticoid receptor in rat liver cells: evidence for plasma membrane bound receptor

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12 December 2020

Do we need new and different glucocorticoids? A re-appraisal of the various congeners and potential alternatives.

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12 December 2020

0.25% prednicarbate cream and the corresponding vehicle induce less skin atrophy than 0.1% betamethasone-17-valerate cream and 0.05% clobetasol-17-propionate cream

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12 December 2020

Topical mometasone furoate and betamethasone-17-valerate decrease collagen synthesis to a similar extent in human skin in vivo

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12 December 2020

Dose-response relationship of topically applied methylprednisolone aceponate (MPA) in healthy volunteers

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12 December 2020

Systemic effects of topically applied methylprednisolone aceponate in healthy volunteers

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12 December 2020

Relative lack of systemic effects of mometasone furoate on Langerhans cells of mice after topical administration as compared with other glucocorticosteroids

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12 December 2020

Differential effect of medium potent nonhalogenated double-ester-type and conventional glucocorticoids on proliferation and chemotaxis of fibroblasts in vitro

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12 December 2020

Modern topical glucocorticoids and anti-infectives for superinfected atopic eczema: Do prednicarbate and didecyldimethylammoniumchloride form a rational combination?

1 reference

12 December 2020

Glucocorticoid receptors in human synovial tissue and relative receptor affinities of glucocorticoid-21-esters

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12 December 2020

Sodium retention and edema from percutaneous absorption of fludrocortisone acetate

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12 December 2020

Heterogeneity of Glucocorticoid Binders: A Unique and a Classical Dexamethasone-Binding Site in Bovine Tissues*

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12 December 2020

Comparison of the local and systemic side effects of methylprednisolone aceponate and mometasone furoate applied as ointments with equal antiinflammatory activity

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12 December 2020

An appraisal of the methods used in the assessment of atrophy from topical corticosteroids

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12 December 2020

Topical glucocorticoids of the non-fluorinated double-ester type. Lack of atrophogenicity in normal skin as assessed by high-frequency ultrasound

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12 December 2020

The effect of topically applied compound F in selected dermatoses

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12 December 2020

Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans

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12 December 2020

Topical corticosteroids and unwanted local effects. Improving the benefit/risk ratio

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12 December 2020

Contact allergies to topical corticosteroids: 10 cases of contact dermatitis

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12 December 2020

A mechanistic basis for distinct mineralocorticoid and glucocorticoid receptor transcriptional specificities

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12 December 2020

Topical glucocorticoids with improved benefit/risk ratio: Do they exist?

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12 December 2020

Benefit/risk ratio of new drugs: for whom? Discussion paper

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12 December 2020

Corticosteroid-induced atrophy of the skin with telangiectasia. A clinical and experimental study

1 reference

12 December 2020

10.2165/00002018-199614060-00003

Identifiers

DOI

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Dimensions Publication ID

27 September 2017

1011988688

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