Manipulation of the Th1/Th2 cell balance: an approach to treat human autoimmune diseases? (Q41167186)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8871762%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

review article

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title

Manipulation of the Th1/Th2 cell balance: an approach to treat human autoimmune diseases? (English)

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20 October 2019

2

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20 October 2019

author name string

L Adorini

series ordinal

1

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20 October 2019

S Trembleau

series ordinal

3

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20 October 2019

publication date

1 January 1996

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20 October 2019

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20 October 2019

volume

23

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20 October 2019

issue

1

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20 October 2019

page(s)

53-68

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Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production

20 October 2019

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Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets

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Developmental commitment to the Th2 lineage by extinction of IL-12 signaling.

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Regulation of interleukin-12 signal transduction during T helper phenotype development

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

21 January 2018

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

21 January 2018

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Recombinant interleukin-12 suppresses the synthesis of immunoglobulin E by interleukin-4 stimulated human lymphocytes

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21 January 2018

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Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

21 January 2018

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The role of IL-12 in the induction of organ-specific autoimmune diseases

21 January 2018

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Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype

21 January 2018

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Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone

21 January 2018

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Islet-specific T-cell clones from the NOD mouse respond to beta-granule antigen

21 January 2018

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Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

21 January 2018

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Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

21 January 2018

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CD4+ beta islet cell-reactive T cell clones that suppress autoimmune diabetes in nonobese diabetic mice

21 January 2018

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Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

21 January 2018

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Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential

21 January 2018

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Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

21 January 2018

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Encephalitogenic Th1 cells are inhibited by Th2 cells with related peptide specificity: relative roles of interleukin (IL)-4 and IL-10.

21 January 2018

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In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice

21 January 2018

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Insulitis in type 1 (insulin-dependent) diabetes mellitus in man--macrophages, lymphocytes, and interferon-gamma containing cells

21 January 2018

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Human Th1 and Th2 cells: functional properties, regulation of development and role in autoimmunity

21 January 2018

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Divergent T-cell cytokine patterns in inflammatory arthritis

21 January 2018

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Lymphokine production by human T cells in disease states

21 January 2018

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Extent of T cell receptor ligation can determine the functional differentiation of naive CD4+ T cells

21 January 2018

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The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model

21 January 2018

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The injection of deaggregated gamma globulins in adult mice induces antigen-specific unresponsiveness of T helper type 1 but not type 2 lymphocytes

21 January 2018

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Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice

21 January 2018

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CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3.

21 January 2018

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Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes

21 January 2018

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Targeting autoantigen to B cells prevents the induction of a cell-mediated autoimmune disease in rats

21 January 2018

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Prevention of experimental allergic encephalomyelitis in rats by targeting autoantigen to B cells: evidence that the protective mechanism depends on changes in the cytokine response and migratory properties of the autoantigen-specific T cells

21 January 2018

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Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering

21 January 2018

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21 January 2018

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CD4+ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion

21 January 2018

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Islet cell antigens in insulin-dependent diabetes: Pandora's box revisited

21 January 2018

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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

21 January 2018

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Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

21 January 2018

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Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells

21 January 2018

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Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands

21 January 2018

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The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.

21 January 2018

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Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

21 January 2018

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Th2 cell clonal anergy as a consequence of partial activation

21 January 2018

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Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants

21 January 2018

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Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

21 January 2018

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T cell receptor antagonist peptides are highly effective inhibitors of experimental allergic encephalomyelitis

21 January 2018

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Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production

21 January 2018

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Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand

21 January 2018

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A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis

21 January 2018

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A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis

21 January 2018

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21 January 2018

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Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor

21 January 2018

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Interleukin-12/T cell stimulating factor, a cytokine with multiple effects on T helper type 1 (Th1) but not on Th2 cells

21 January 2018

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Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

21 January 2018

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Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

21 January 2018

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Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice

21 January 2018

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Antibodies to interleukin 12 abrogate established experimental colitis in mice

21 January 2018

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B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation

21 January 2018

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Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

21 January 2018

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Macrophage deactivation by interleukin 10

21 January 2018

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IL-10 immunosuppression in transplantation

21 January 2018

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Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

21 January 2018

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Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

21 January 2018

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Effect of adjuvant therapy on development of diabetes in mouse and man.

21 January 2018

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Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis

21 January 2018

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Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

21 January 2018

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The regulation of immunity to Leishmania major

21 January 2018

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Recombinant interleukin 12 cures mice infected with Leishmania major

21 January 2018

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Evidence for the stochastic acquisition of cytokine profile by CD4+ T cells activated in a T helper type 2-like responsein vivo

21 January 2018

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Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

21 January 2018

1 reference

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10.3109/08916939608995329

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8871762%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1 reference