Getting the glycosylation right: implications for the biotechnology industry (Q41176922)

27 September 2017

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title

Getting the glycosylation right: implications for the biotechnology industry (English)

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27 September 2017

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Jenkins N

1

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27 September 2017

Parekh RB

series ordinal

2

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27 September 2017

James DC

series ordinal

3

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27 September 2017

1 August 1996

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27 September 2017

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27 September 2017

14

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27 September 2017

8

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27 September 2017

975-981

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https://scigraph.springernature.com/pub.10.1038/nbt0896-975

27 September 2017

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Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation

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Immunotherapeutic potential of antibodies produced in plants

21 January 2018

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Biochemical analysis of the N-glycosylation pathway in baculovirus-infected lepidopteran insect cells.

21 January 2018

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Intrinsic glycosylation potentials of insect cell cultures and insect larvae

21 January 2018

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Specificity of human natural antibody to recombinant tissue-type plasminogen activator (t-PA) expressed in mouse C127 cells

21 January 2018

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Control of IgG/Fc glycosylation: a comparison of oligosaccharides from chimeric human/mouse and mouse subclass immunoglobulin Gs.

21 January 2018

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Molecular cloning of cytidine monophospho-N-acetylneuraminic acid hydroxylase. Regulation of species- and tissue-specific expression of N-glycolylneuraminic acid

21 January 2018

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N-linked glycosylation of tissue plasminogen activator in Namalwa cells

21 January 2018

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Transfection of N-acetylglucosaminyltransferase III gene suppresses expression of hepatitis B virus in a human hepatoma cell line, HB611.

21 January 2018

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A hepatic reticuloendothelial cell receptor specific for SO4-4GalNAcβ1, 4GlcNAcβ1,2Manα that mediates rapid clearance of lutropin

21 January 2018

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Clearing up glycoprotein hormones

21 January 2018

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Different culture methods lead to differences in glycosylation of a murine IgG monoclonal antibody

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT0896-975

Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation

21 January 2018

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Mammalian glycosyltransferases: genomic organization and protein structure

21 January 2018

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7 January 2021

Molecular cloning of eukaryotic glycoprotein and glycolipid glycosyltransferases: a survey

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7 January 2021

Biological roles of oligosaccharides: all of the theories are correct

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7 January 2021

The oligosaccharides of glycoproteins: bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties

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7 January 2021

Characterization and evaluation of a recombinant hepatitis B vaccine expressed in yeast defective for N-linked hyperglycosylation

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7 January 2021

Comparison of the carbohydrate moieties of recombinant soluble Fc epsilon receptor (sFc epsilon RII/sCD23) expressed in Saccharomyces cerevisiae and Chinese hamster ovary cells. Different O-glycosylation sites are used by yeast and mammalian cells

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Characterization of a human glycoprotein (erythropoietin) produced in cultured tobacco cells

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Biosynthesis and secretion of human interleukin 2 glycoprotein variants from baculovirus-infected Sf21 cells. Characterization of polypeptides and posttranslational modifications

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Oligosaccharide processing in the expression of human plasminogen cDNA by lepidopteran insect (Spodoptera frugiperda) cells

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Does endogenous glycosylation prevent the use of mouse monoclonal antibodies as cancer therapeutics?

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7 January 2021

Structural characterization of the N-glycans of a humanized anti-CD18 murine immunoglobulin G

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7 January 2021

Glycosylation and biological activity of CAMPATH-1H expressed in different cell lines and grown under different culture conditions

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7 January 2021

Glycosylation of the variable region of immunoglobulin G--site specific maturation of the sugar chains

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7 January 2021

Human natural anti-Gal IgG regulates alternative complement pathway activation on bacterial surfaces

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7 January 2021

Characterization of the glycosylation of a human IgM produced by a human-mouse hybridoma.

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Immunogenicity of N-glycolylneuraminic acid-containing carbohydrate chains of recombinant human erythropoietin expressed in Chinese hamster ovary cells

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7 January 2021

Fluorophore-labeled carbohydrate analysis of immunoglobulin fusion proteins: Correlation of oligosaccharide content with in vivo clearance profile

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7 January 2021

Structural Analysis of the Sialylated N- and O-Linked Carbohydrate Chains of Recombinant Human Erythropoietin Expressed in Chinese Hamster Ovary Cells. Sialylation Patterns and Branch Location of Dimeric N-acetyllactosamine Units

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Tissue plasminogen activator coexpressed in Chinese hamster ovary cells with alpha(2,6)-sialyltransferase contains NeuAc alpha(2,6)Gal beta(1,4)Glc-N-AcR linkages

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Construction of stable BHK-21 cells coexpressing human secretory glycoproteins and human Gal(beta 1-4)GlcNAc-R alpha 2,6-sialyltransferase alpha 2,6-linked NeuAc is preferentially attached to the Gal(beta 1-4)GlcNAc(beta 1-2)Man(alpha 1-3)-branch of

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7 January 2021

Glycosyltransferase mutants: key to new insights in glycobiology.

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7 January 2021

Purification and characterization of three forms of differently glycosylated recombinant human granulocyte-macrophage colony-stimulating factor

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https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Structural study of the sugar moieties of monoclonal antibodies secreted by human-mouse hybridoma

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Remodeling of mouse milk glycoconjugates by transgenic expression of a human glycosyltransferase

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7 January 2021

Transforming growth factor beta up-regulates expression of the N-acetylglucosaminyltransferase V gene in mouse melanoma cells

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7 January 2021

Rheumatoid factor avidity in patients with rheumatoid arthritis: identification of pathogenic RFs which correlate with disease parameters and with the gal(0) glycoform of IgG.

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7 January 2021

Agalactosyl glycoforms of IgG autoantibodies are pathogenic

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7 January 2021

The Major N-Linked Carbohydrate Chains from Human Urokinase. The Occurrence of 4-O-sulfated, (alpha2-6)-sialylated or (alpha1-3)-fucosylated N-acetylgalactosamine(beta1-4)-N-acetylglucosamine Elements

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Molecular basis of recognition by the glycoprotein hormone-specific N-acetylgalactosamine-transferase

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Biosynthesis of sulfated glycoprotein-N-glycans present in recombinant human tissue plasminogen activator

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Glycosylated human recombinant interleukin-1 alpha, neo interleukin-1 alpha, with D-mannose dimer exhibits selective activities in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

The major form of the murine asialoglycoprotein receptor: cDNA sequence and expression in liver, testis and epididymis

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Glycosylation of interleukin-6 purified from normal human blood mononuclear cells.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Effect of culture conditions on IgM antibody structure, pharmacokinetics and activity

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Characterization of changes in the glycosylation pattern of recombinant proteins from BHK-21 cells due to different culture conditions

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Changes of monosaccharide availability of human hybridoma lead to alteration of biological properties of human monoclonal antibody

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Glucose-limited chemostat culture of Chinese hamster ovary cells producing recombinant human interferon-gamma

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Effect of lipid supplements on the production and glycosylation of recombinant interferon-gamma expressed in CHO cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

The effect of increasing nucleotide-sugar concentrations on the incorporation of sugars into glycoconjugates in rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Characterization of a recombinant antibody produced in the course of a high yield fed-batch process

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

N-glycans of recombinant human interferon-gamma change during batch culture of chinese hamster ovary cells.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Effect of different cell culture conditions on the polypeptide integrity and N-glycosylation of a recombinant model glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactin

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Intracellular folding of tissue-type plasminogen activator. Effects of disulfide bond formation on N-linked glycosylation and secretion

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Expression of FSH in CHO cells. II. Stimulation of hFSH expression levels by defined medium supplements

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Production of tPA in recombinant CHO cells under oxygen-limited conditions

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Monosaccharide and oligosaccharide analysis of isoelectric focusing-separated and blotted granulocyte colony-stimulating factor glycoforms using high-pH anion-exchange chromatography with pulsed amperometric detection

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Ammonia affects the glycosylation patterns of recombinant mouse placental lactogen-I by chinese hamster ovary cells in a pH-dependent manner.

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Glycosidase activities in Chinese hamster ovary cell lysate and cell culture supernatant

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Isolation and properties of a soluble sialidase from the culture fluid of Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Cloning and expression of a soluble sialidase from Chinese hamster ovary cells: sequence alignment similarities to bacterial sialidases

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Purification and characterization of alpha-L-fucosidase from Chinese hamster ovary cell culture supernatant

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Glycosidase activities of the 293 and NS0 cell lines, and of an antibody-producing hybridoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Influence of cell- and media-derived factors on the integrity of a human monoclonal antibody after secretion into serum-free cell culture supernatants

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Synthesis of a glycopeptide carrying a N-linked core pentasaccharide

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Rationally designed syntheses of high-mannose and complex type undecasaccharides

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

alpha-galactosyl (Galalpha1-3Galbeta1-4GlcNAc-R) epitopes on human cells: synthesis of the epitope on human red cells by recombinant primate alpha1,3galactosyltransferase expressed in E.coli

1 reference

https://api.crossref.org/works/10.1038%2FNBT0896-975

7 January 2021

Identifiers

DOI

10.1038/NBT0896-975

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Dimensions Publication ID

27 September 2017

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