The role of the C-terminal domain of I kappa B alpha in protein degradation and stabilization (Q41199539)

28 September 2017

The role of the C-terminal domain of I kappa B alpha in protein degradation and stabilization (English)

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28 September 2017

P Beauparlant

1

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28 September 2017

R Lin

series ordinal

2

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28 September 2017

J Hiscott

series ordinal

3

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28 September 2017

language of work or name

English

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publication date

1 May 1996

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Journal of Biological Chemistry

28 September 2017

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28 September 2017

271

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28 September 2017

10690-10696

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28 September 2017

18

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The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits

28 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

p105 and p98 precursor proteins play an active role in NF-kappa B-mediated signal transduction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Rel-associated pp40: an inhibitor of the rel family of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Proteasomes: protein degradation machines of the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Inducible degradation of I kappa B alpha in vitro and in vivo requires the acidic C-terminal domain of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Constitutive phosphorylation of I kappa B alpha by casein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Cactus protein degradation mediates Drosophila dorsal-ventral signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Induction of monocytic differentiation and NF-kappa B-like activities by human immunodeficiency virus 1 infection of myelomonoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

Subcellular redistribution of HTLV-1 Tax protein by NF-kappa B/Rel transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.18.10690

21 January 2018

Identifiers

DOI

10.1074/JBC.271.18.10690

1 reference

28 September 2017

1 reference