C-X-C motif chemokine ligand 9 (Q411999)

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mammalian protein found in Homo sapiens

• HuMIG
• chemokine (C-X-C motif) ligand 9
• C-X-C motif chemokine 9
• MIG
• small-inducible cytokine B9
• monokine induced by gamma interferon
• gamma-interferon-induced monokine
• monokine induced by interferon-gamma
• CXCL9
• Chemokine CXCL9

edit

Language	Label	Description	Also known as
English	C-X-C motif chemokine ligand 9	mammalian protein found in Homo sapiens	HuMIG chemokine (C-X-C motif) ligand 9 C-X-C motif chemokine 9 MIG small-inducible cytokine B9 monokine induced by gamma interferon gamma-interferon-induced monokine monokine induced by interferon-gamma CXCL9 Chemokine CXCL9

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q07325

part of

Chemokine interleukin-8-like superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q07325

Chemokine interleukin-8-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXC Chemokine domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

CXC chemokine, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q07325

encoded by

CXCL9

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q07325

molecular function

cytokine activity

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

CXCR3 chemokine receptor binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IDA

chemokine activity

determination method

IDA

IEA

TAS

3 references

retrieved

16 July 2018

stated in

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

16 July 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

16 July 2018

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IDA

protein binding

determination method

IPI

4 references

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IPI

retrieved

8 April 2019

stated in

Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IPI

retrieved

8 April 2019

stated in

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IPI

retrieved

8 April 2019

stated in

Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IPI

chemokine activity

determination method

IBA

IDA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

cell component

extracellular region

determination method

TAS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

external side of plasma membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

extracellular space

determination method

IBA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

HuMig: a new human member of the chemokine family of cytokines

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

intracellular anatomical structure

determination method

IEA

1 reference

retrieved

10 September 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IEA

biological process

G protein-coupled receptor signaling pathway

determination method

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

chemokine-mediated signaling pathway

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

cell-cell signaling

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

HuMig: a new human member of the chemokine family of cytokines

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

positive regulation of release of sequestered calcium ion into cytosol

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IDA

positive regulation of cAMP-mediated signaling

determination method

IDA

1 reference

retrieved

10 September 2018

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IDA

chemotaxis

determination method

IDA

IEA

TAS

3 references

retrieved

8 April 2019

stated in

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IDA

positive regulation of leukocyte chemotaxis

determination method

IBA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IBA

cellular defense response

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

positive regulation of myoblast fusion

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

response to lipopolysaccharide

determination method

IBA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IBA

regulation of cell population proliferation

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IDA

positive regulation of myoblast differentiation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

defense response to virus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

immune response

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

signal transduction

determination method

TAS

2 references

retrieved

8 April 2019

stated in

Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

defense response

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

A macrophage mRNA selectively induced by gamma-interferon encodes a member of the platelet factor 4 family of cytokines

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

inflammatory response

determination method

IBA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

T cell chemotaxis

determination method

IBA

1 reference

retrieved

16 July 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IBA

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method

IDA

1 reference

retrieved

21 June 2018

stated in

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07325&geneProductId=UniProtKB:Q07325

determination method

IDA

regulation of signaling receptor activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

adenylate cyclase-activating G protein-coupled receptor signaling pathway

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4

GOA

curator

UniProt

UniProt protein ID

Q07325

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IDA

response to bacterium

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IEA

neutrophil chemotaxis

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

leukocyte chemotaxis

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

antimicrobial humoral immune response mediated by antimicrobial peptide

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

cellular response to lipopolysaccharide

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07325

determination method

IBA

Gene Atlas image

PBB GE CXCL9 203915 at fs.png
732 × 530; 10 KB

0 references

exact match

http://purl.uniprot.org/uniprot/Q07325

1 reference

stated in

Identifiers.org

has part(s)

Chemokine interleukin-8-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q07325

CXC chemokine, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q07325

CXC Chemokine domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q07325

Identifiers

MeSH descriptor ID

D054370

subject named as

Chemokine CXCL9

0 references

MeSH tree code

D12.644.276.374.200.120.450

0 references

D12.776.467.374.200.120.450

0 references

D23.125.300.120.450

0 references

D23.469.200.120.450

0 references

D23.529.374.200.120.450

0 references

RefSeq protein ID

NP_002407

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

4283

UniProt protein ID

Q07325

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q07325

Ensembl protein ID

ENSP00000354901

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000354901

Freebase ID

/m/027fgxk

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

17502307

0 references

OpenAlex ID

C17502307

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

UMLS CUI

C1335989

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(8 entries)

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• bswiki CXCL9
• cswiki CXCL9
• dewiki CXC-Ligand 9
• enwiki CXCL9
• shwiki CXCL9
• srwiki CXCL9
• ukwiki CXCL9
• zhwiki CXCL9

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

edit

Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q411999&oldid=2022901355"