irinotecan (Q412197)

irinotecan (English)

19 October 2016

C₃₃H₃₈N₄O₆

1 reference

irinotecan (English)

19 November 2016

CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

1 reference

irinotecan (English)

19 November 2016

CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

1 reference

World Health Organisation international non-proprietary name

irinotecan (English)

19 November 2016

1 reference

14 February 2018

irinotecan (English)

1 reference

Taiwanofungus camphoratus

irinotecan (English)

19 October 2016

1 reference

Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from Antrodia camphorata

liquorice

1 reference

Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.

medical condition treated

1 reference

13 December 2016

1 reference

non-small-cell lung carcinoma

13 December 2016

1 reference

13 December 2016

1 reference

13 December 2016

colonic benign neoplasm

1 reference

13 December 2016

1 reference

13 December 2016

2 references

13 December 2016

2 October 2018

1 reference

13 December 2016

1 reference

2 October 2018

germ cell cancer

1 reference

alveolar rhabdomyosarcoma

2 October 2018

1 reference

2 October 2018

colon adenocarcinoma

1 reference

pancreatic adenocarcinoma

2 October 2018

1 reference

2 October 2018

brain cancer

1 reference

2 October 2018

rectum adenocarcinoma

1 reference

neuroblastoma, susceptibility to

2 October 2018

1 reference

Food and Drug Administration

2 October 2018

14 June 1996

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/7673326042

2 November 2018

reference URL

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf

significant drug interaction

amiodarone

1 reference

High-priority drug–drug interactions for use in electronic health records

amprenavir

1 reference

High-priority drug–drug interactions for use in electronic health records

aprepitant

1 reference

High-priority drug–drug interactions for use in electronic health records

atazanavir

1 reference

High-priority drug–drug interactions for use in electronic health records

cimetidine

1 reference

High-priority drug–drug interactions for use in electronic health records

clarithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

darunavir

1 reference

High-priority drug–drug interactions for use in electronic health records

diltiazem

1 reference

High-priority drug–drug interactions for use in electronic health records

erythromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

fluconazole

1 reference

High-priority drug–drug interactions for use in electronic health records

fosamprenavir

1 reference

High-priority drug–drug interactions for use in electronic health records

indinavir

1 reference

High-priority drug–drug interactions for use in electronic health records

itraconazole

1 reference

High-priority drug–drug interactions for use in electronic health records

Ketoconazole

1 reference

High-priority drug–drug interactions for use in electronic health records

lopinavir

1 reference

High-priority drug–drug interactions for use in electronic health records

nefazodone

1 reference

High-priority drug–drug interactions for use in electronic health records

nelfinavir

1 reference

High-priority drug–drug interactions for use in electronic health records

ritonavir

1 reference

High-priority drug–drug interactions for use in electronic health records

saquinavir

1 reference

High-priority drug–drug interactions for use in electronic health records

telithromycin

1 reference

High-priority drug–drug interactions for use in electronic health records

tipranavir

1 reference

High-priority drug–drug interactions for use in electronic health records

verapamil

1 reference

High-priority drug–drug interactions for use in electronic health records

voriconazole

1 reference

High-priority drug–drug interactions for use in electronic health records

idelalisib

side effect

bone marrow failure

1 reference

sourcing circumstances

hypothetically

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

subject has role

DNA polymerase inhibitors

1 reference

5 March 2018

topoisomerase inhibitor

1 reference

5 March 2018

phytogenic antineoplastic agents

1 reference

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

C051890

topoisomerase I inhibitor

15 March 2018

1 reference

InChI=1S/C33H38N4O6/c1-3-22-23-16-21(43-32(40)36-14-10-20(11-15-36)35-12-6-5-7-13-35)8-9-27(23)34-29-24(22)18-37-28(29)17-26-25(30(37)38)19-42-31(39)33(26,41)4-2/h8-9,16-17,20,41H,3-7,10-15,18-19H2,1-2H3/t33-/m0/s1

Medical Subject Headings

15 March 2018

0 references

Irinotecan

0 references

Identifiers

InChI

1 reference

UWKQSNNFCGGAFS-XIFFEERXSA-N

irinotecan (English)

19 November 2016

2 references

irinotecan (English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

97682-44-5

2 references

Global Substance Registration System

UNII

7673326042

UWKQSNNFCGGAFS-XIFFEERXSA-N

irinotecan (English)

19 November 2016

10 April 2021

https://commonchemistry.cas.org/detail?cas_rn=97682-44-5

1 reference

Irinotecan (English)

19 November 2016

1 reference

irinotecan (English)

19 November 2016

Reaxys registry number

4839096

1 reference

irinotecan (English)

19 October 2016

mapping relation type

1 reference

IRINOTECAN (English)

19 November 2016

1 reference

Hazardous Substances Data Bank

IRINOTECAN (English)

19 November 2016

1 reference

1 reference

28 October 2019

IRINOTECAN (English)

10 May 2021

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

691-567-9

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.219.260

27 December 2018

ECHA Substance Infocard ID

(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate (English)

quotation

CAS no.: 97682-44-5 (English)

100.219.260

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.219.260

27 December 2018

(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate (English)

quotation

CAS no.: 97682-44-5 (English)

1 reference