Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1. (Q41245660)

28 September 2017

Mutant SOD1 G93A microglia have an inflammatory phenotype and elevated production of MCP-1. (English)

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28 September 2017

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Siranush A Sargsyan

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Daniel J Blackburn

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Siân C Barber

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1 October 2009

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1450-1455

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describes a project that uses

28 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2889291/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.

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Neuronal chemokines: versatile messengers in central nervous system cell interaction

28 September 2017

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EMR1, the human homolog of F4/80, is an eosinophil-specific receptor

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Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice.

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

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ATP mediates rapid microglial response to local brain injury in vivo

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Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration

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Circulating levels of tumour necrosis factor-alpha and its soluble receptors are increased in the blood of patients with amyotrophic lateral sclerosis

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Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice.

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Intrathecal synthesis of monocyte chemoattractant protein-1 (MCP-1) in amyotrophic lateral sclerosis: further evidence for microglial activation in neurodegeneration

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Increased cytotoxic potential of microglia from ALS-transgenic mice

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12 December 2020

Effect of bacterial wall lipopolysaccharide (LPS) on morphology, motility, and cytoskeletal organization of microglia in cultures

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12 December 2020

Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis

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12 December 2020

Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia

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12 December 2020

Elevation of MCP-1 and MCP-1/VEGF ratio in cerebrospinal fluid of amyotrophic lateral sclerosis patients

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12 December 2020

10.1097/WNR.0B013E328331E8FA

Identifiers

DOI

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28 September 2017

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28 September 2017

PubMed publication ID

19752764

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