The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances (Q41258581)

28 September 2017

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title

The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances (English)

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autosomal dominant polycystic kidney disease

28 September 2017

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autosomal dominant polycystic kidney

inferred from title

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Grantham JJ

1

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28 September 2017

1 December 1996

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American Journal of Kidney Diseases

28 September 2017

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28 September 2017

28

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28 September 2017

6

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28 September 2017

788-803

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A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16

28 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Autosomal dominant polycystic kidney disease: localization of the second gene to chromosome 4q13-q23

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

The gene for autosomal dominant polycystic kidney disease lies in a 750-kb CpG-rich region

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Analysis of the genomic sequence for the autosomal dominant polycystic kidney disease (PKD1) gene predicts the presence of a leucine-rich repeat. The American PKD1 Consortium (APKD1 Consortium)

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

The PKD1 gene produces a developmentally regulated protein in mesenchyme and vasculature

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Gene transfer into the kidney: promise for unravelling disease mechanisms, limitations for human gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Polycystic kidney disease: neoplasia in disguise

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Autosomal-dominant polycystic kidney disease in the rat

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Cyst formation and growth in autosomal dominant polycystic kidney disease

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Expression of differentiation antigens and growth-related genes in normal kidney, autosomal dominant polycystic kidney disease, and renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic mice

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

c-myc as an inducer of polycystic kidney disease in transgenic mice

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Cyst-derived cells do not exhibit accelerated growth or features of transformed cells in vitro

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Apoptosis and loss of renal tissue in polycystic kidney diseases

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Deregulation of cell survival in cystic and dysplastic renal development.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Urinary lipid bodies in polycystic kidney disease

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Expression of clusterin in human renal diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Abnormal polarization of EGF receptors and autocrine stimulation of cyst epithelial growth in human ADPKD

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

C-fos expression is hypersensitive to serum-stimulation in cultured cystic kidney cells from the C57BL/6J-cpk mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

A new method for studying human polycystic kidney disease epithelia in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Impaired tubulogenesis of cyst-derived cells from autosomal dominant polycystic kidneys

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

In vitro fluid secretion by epithelium from polycystic kidneys

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Renal epithelial fluid secretion and cyst growth: the role of cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

In vitro formation and expansion of cysts derived from human renal cortex epithelial cells

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Autosomal dominant polycystic kidney disease

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Ultrastructure and function of cysts from human adult polycystic kidneys

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation?

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Intra- and extracellular proteins in human normal and polycystic kidney epithelial cells

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Extracellular matrix formation by epithelial cells from human polycystic kidney cysts in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Abnormal extracellular matrix and excessive growth of human adult polycystic kidney disease epithelia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Coexpression of extracellular matrix glycoproteins undulin and tenascin in human autosomal dominant polycystic kidney disease

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Renal histology in polycystic kidney disease with incipient and advanced renal failure

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Cytokines in fluids from polycystic kidneys

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

On the probability that kidneys are different in autosomal dominant polycystic disease

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Macropuncture study of polycystic disease in adult human kidneys

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Renal excretion and cyst accumulation of beta 2microglobulin in polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

The secretion of fluid by renal cysts from patients with autosomal dominant polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

In vitro function of cyst epithelium from human polycystic kidney

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Fluid secretion in the nephron: Relation to renal failure

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

A role for CFTR in human autosomal dominant polycystic kidney disease

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Crypts are the site of intestinal fluid and electrolyte secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Modification of disease progression in rats with inherited polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Effect of lovastatin on the development of polycystic kidney disease in the Han:SPRD rat

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https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Methylprednisolone retards the progression of inherited polycystic kidney disease in rodents.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

Taxol inhibits progression of congenital polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0272-6386%2896%2990378-9

7 January 2021

10.1016/S0272-6386(96)90378-9

Identifiers

DOI

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28 September 2017

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PubMed ID

8957030