Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders (Q41264952)

28 September 2017

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title

Controlled release of proteins to tissue transplants for the treatment of neurodegenerative disorders (English)

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28 September 2017

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1

M J Mahoney

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28 September 2017

2

W M Saltzman

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PubMed ID

8961138

28 September 2017

language of work or name

English

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publication date

1 December 1996

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Journal of Pharmaceutical Sciences

28 September 2017

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28 September 2017

85

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28 September 2017

12

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28 September 2017

1276-1281

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Role of growth factors in degeneration and regeneration in the central nervous system; clinical experiences with NGF in Parkinson's and Alzheimer's diseases.

28 September 2017

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7 January 2021

Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease

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7 January 2021

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease

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7 January 2021

Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease.

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7 January 2021

Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

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7 January 2021

Enhanced survival and neuronal differentiation of adrenal chromaffin cells cografted into the striatum with NGF-producing fibroblasts

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7 January 2021

Bridging grafts and transient nerve growth factor infusions promote long-term central nervous system neuronal rescue and partial functional recovery

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7 January 2021

Human nerve growth factor prevents degeneration of basal forebrain cholinergic neurons in primates

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7 January 2021

Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat.

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7 January 2021

Morphological response of axotomized septal neurons to nerve growth factor

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7 January 2021

Controlled release of nerve growth factor from a polymeric implant.

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7 January 2021

Implantation of polymer-encapsulated human nerve growth factor-secreting fibroblasts attenuates the behavioral and neuropathological consequences of quinolinic acid injections into rodent striatum

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7 January 2021

Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

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7 January 2021

Macromolecular permeability across the blood-nerve and blood-brain barriers

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7 January 2021

Transport and elimination of recombinant human NGF during long-term delivery to the brain

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7 January 2021

Distribution of nerve growth factor following direct delivery to brain interstitium

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7 January 2021

NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion

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7 January 2021

Sustained Release of Nerve Growth Factor from Biodegradable Polymer Microspheres

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7 January 2021

Grafting genetically modified cells to the damaged brain: restorative effects of NGF expression

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7 January 2021

Transplantation of a polymer-encapsulated cell line genetically engineered to release NGF.

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7 January 2021

Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain.

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7 January 2021

Transport rates of proteins in porous materials with known microgeometry

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7 January 2021

Polymers for the sustained release of proteins and other macromolecules

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7 January 2021

Controlled release of polypeptides and other macromolecules

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7 January 2021

Controlled release of polypeptides from polyanhydrides

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7 January 2021

Controlled delivery systems for proteins using polyanhydride microspheres

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7 January 2021

Development of poly(ortho esters): a historical overview

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7 January 2021

Biodegradable microspheres as controlled-release tetanus toxoid delivery systems.

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7 January 2021

Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres

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7 January 2021

Controlled release of interleukin-2 from biodegradable microspheres

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7 January 2021

Polyanhydride microspheres as drug carriers. II. Microencapsulation by solvent removal

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7 January 2021

In vivo release profiles of leuprolide acetate from microcapsules prepared with polylactic acids or copoly(lactic/glycolic) acids and in vivo degradation of these polymers

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7 January 2021

Transplantation of neural tissue in polymer capsules

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7 January 2021

Distribution of drugs following controlled delivery to the brain interstitium

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7 January 2021

Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity.

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7 January 2021

Interaction between diffusion and Michaelis-Menten uptake of dopamine after iontophoresis in striatum.

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7 January 2021

Identifiers

DOI

10.1021/JS9601602

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28 September 2017

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PubMed ID

8961138