Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations (Q41298105)

29 September 2017

title

Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations (English)

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29 September 2017

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Moore RC

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29 September 2017

Redhead NJ

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29 September 2017

Selfridge J

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29 September 2017

Hope J

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29 September 2017

Manson JC

5

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29 September 2017

Melton DW

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29 September 2017

language of work or name

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1 September 1995

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29 September 2017

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29 September 2017

volume

13

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29 September 2017

issue

9

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29 September 2017

page(s)

999-1004

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

29 September 2017

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Cystic fibrosis in the mouse by targeted insertional mutagenesis

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Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene

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Atherosclerosis in mice: getting to the heart of a polygenic disorder

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Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

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Distinct prion proteins in short and long scrapie incubation period mice

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Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice.

21 January 2018

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Germ-line transformation of mice

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Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

21 January 2018

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Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

21 January 2018

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Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes.

21 January 2018

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Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins

21 January 2018

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

21 January 2018

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Location of crossovers during gene targeting with insertion and replacement vectors

21 January 2018

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Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy

21 January 2018

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Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells

21 January 2018

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Site-directed point mutations in embryonic stem cells: a gene-targeting tag-and-exchange strategy

21 January 2018

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Rapid and efficient site-specific mutagenesis without phenotypic selection

21 January 2018

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Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells

21 January 2018

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Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells

21 January 2018

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Gene targeting in the mouse

21 January 2018

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7 January 2021

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

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7 January 2021

An animal model for cystic fibrosis made by gene targeting

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7 January 2021

Identification of the cystic fibrosis gene: genetic analysis

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Inherited prion diseases

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7 January 2021

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism

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7 January 2021

Linkage of prion protein and scrapie incubation time genes

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7 January 2021

A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency

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7 January 2021

Structure and polymorphism of the mouse prion protein gene

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7 January 2021

Spontaneous neurodegeneration in transgenic mice with mutant prion protein

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7 January 2021

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

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7 January 2021

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

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7 January 2021

Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus.

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7 January 2021

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

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7 January 2021

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

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7 January 2021

Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells

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7 January 2021

A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells

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7 January 2021

Gene targeting using a mouse HPRT minigene/HPRT-deficient embryonic stem cell system: inactivation of the mouse ERCC-1 gene

1 reference

https://api.crossref.org/works/10.1038%2FNBT0995-999

7 January 2021

A simple salting out procedure for extracting DNA from human nucleated cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT0995-999

7 January 2021

In vitro translation of hypoxanthine/guanine phosphoribosyltransferase mRNA: characterization of a mouse neuroblastoma cell line that has elevated levels of hypoxanthine/guanine phosphoribosyltransferase protein

1 reference

https://api.crossref.org/works/10.1038%2FNBT0995-999

7 January 2021

Identifiers

DOI

10.1038/NBT0995-999

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release_nvvjtmsvqbb55nmll6gb54ddwq

29 September 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/nvvjtmsvqbb55nmll6gb54ddwq

24 November 2022

mapped directly with Wikidata item

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