Neurotoxic and neuroprotective roles of nitric oxide in cerebral ischaemia (Q41301348)

29 September 2017

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title

Neurotoxic and neuroprotective roles of nitric oxide in cerebral ischaemia (English)

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29 September 2017

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Dalkara T

1

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PubMed ID

8989627

29 September 2017

Moskowitz MA

series ordinal

2

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29 September 2017

1 January 1997

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International Review of Neurobiology

29 September 2017

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29 September 2017

40

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29 September 2017

319-336

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Nitric oxide mediates the sustained opening of NMDA receptor-gated ionic channels which follows transient excitotoxic exposure in hippocampal slices.

29 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Inhibition of rat cerebellar nitric oxide synthase by 7-nitro indazole and related substituted indazoles

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Substrate-dependent regulation of intracellular amino acid concentrations in cultured bovine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Localization of nitric oxide synthase indicating a neural role for nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide: a signal for ADP-ribosylation of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Mono-L-arginine-containing compounds dilate piglet pial arterioles via an endothelium-derived relaxing factor-like substance.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Early endonuclease activation following reversible focal ischemia in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Calmodulin is a subunit of nitric oxide synthase from macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide promotes arteriolar dilation during cortical spreading depression in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

A novel neuronal messenger molecule in brain: the free radical, nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Gases as biological messengers: nitric oxide and carbon monoxide in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide reduces depolarization-induced calcium influx in PC12 cells by a cyclic GMP-mediated mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthase: Irreversible inhibition by L-NG-Nitroarginine in brain in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide mediates vasodilatation in response to activation of N-methyl-D-aspartate receptors in brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide and the cerebral circulation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Multiple types of nitrogen monoxide synthase-/NADPH diaphorase-containing neurons in the human cerebral neocortex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

The NO hypothesis: possible effects of a short-lived, rapidly diffusible signal in the development and function of the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide signaling in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthases: properties and catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Cytokine-activated endothelial cells express an isotype of nitric oxide synthase which is tetrahydrobiopterin-dependent, calmodulin-independent and inhibited by arginine analogs with a rank-order of potency characteristic of activated macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide: pathophysiological mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Pressure-induced myogenic activation of cat cerebral arteries is dependent on intact endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Targeted disruption of the neuronal nitric oxide synthase gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Hypertension in mice lacking the gene for endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthase inhibition and cerebrovascular regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Inducible nitric oxide synthase gene expression in brain following cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Regulation of blood-brain barrier endothelial cells by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthase expression in vagal complex following vagotomy in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide production during focal cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide as an antioxidant

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric Oxide-Mediated Apoptosis in Murine Mastocytoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Lesion-induced NADPH-diaphorase reactivity in neocortical pyramidal neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide as a signal in blood vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Vulnerability of cultured cortical neurons to damage by excitotoxins: differential susceptibility of neurons containing NADPH-diaphorase.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthesis in the CNS, endothelium and macrophages differs in its sensitivity to inhibition by arginine analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Potential genotoxicity of chronically elevated nitric oxide: a review

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Mammalian synthesis of nitrite, nitrate, nitric oxide, and N-nitrosating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide: biosynthesis and biological significance

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Selective inhibition of the inducible nitric oxide synthase by aminoguanidine

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Cultured endothelial cells maintain their L-arginine level despite the continuous release of EDRF

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

L-NG-nitro arginine (L-NOARG), a novel, L-arginine-reversible inhibitor of endothelium-dependent vasodilatation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

L-arginine infusion promotes nitric oxide-dependent vasodilation, increases regional cerebral blood flow, and reduces infarction volume in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

L-arginine dilates rat pial arterioles by nitric oxide-dependent mechanisms and increases blood flow during focal cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Synthesis of nitric oxide in CNS glial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Cloned human brain nitric oxide synthase is highly expressed in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Calcium ion effects on guanylate cyclase of brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide controls oscillatory activity in thalamocortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide synthesis and regional cerebral blood flow responses to hypercapnia and hypoxia in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide inhibits 3H-glutamate transport in synaptosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

In the rat, endogenous nitric oxide modulates the response of the hypothalamic-pituitary-adrenal axis to interleukin-1 beta, vasopressin, and oxytocin.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide activates cyclooxygenase enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

EPR spin-trapping study of nitric oxide formation during bilateral carotid occlusion in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

An electrochemical microprobe for detecting nitric oxide release in brain tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Intracellular and extracellular changes of [Ca2+] in hypoxia and ischemia in rat brain in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Inhibition of nitric oxide synthesis induces a significant reduction in local cerebral blood flow in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Endonuclease activation following focal ischemic injury in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide in the regulation of blood flow and arterial pressure

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Mapping of the Genes Encoding Human Inducible and Endothelial Nitric Oxide Synthase (NOS2 and NOS3) to the Pericentric Region of Chromosome 17 and to Chromosome 7, Respectively

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide donors increase blood flow and reduce brain damage in focal ischemia: evidence that nitric oxide is beneficial in the early stages of cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2808%2960726-6

7 January 2021

10.1016/S0074-7742(08)60726-6

Identifiers

DOI

0 references

PubMed ID

8989627

1 reference

PubMed ID

8989627