Gαq controls rheumatoid arthritis via regulation of Th17 differentiation (Q41318355)

29 September 2017

title

Gαq controls rheumatoid arthritis via regulation of Th17 differentiation (English)

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29 September 2017

1 reference

Yuan Liu

1

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29 September 2017

Dashan Wang

series ordinal

2

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29 September 2017

Fang Li

series ordinal

3

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29 September 2017

Guixiu Shi

series ordinal

4

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29 September 2017

publication date

3 March 2015

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Immunology & Cell Biology

29 September 2017

published in

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29 September 2017

volume

93

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29 September 2017

issue

7

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29 September 2017

page(s)

616-624

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Heterotrimeric G protein activation by G-protein-coupled receptors

29 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FICB.2015.13

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Transgenic Galphaq overexpression induces cardiac contractile failure in mice

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Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

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A functional polymorphism of the Galphaq (GNAQ) gene is associated with accelerated mortality in African-American heart failure

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Identification of an alternative G{alpha}q-dependent chemokine receptor signal transduction pathway in dendritic cells and granulocytes

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G alpha q-containing G proteins regulate B cell selection and survival and are required to prevent B cell-dependent autoimmunity

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The pathogenesis of rheumatoid arthritis

21 January 2018

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Expression of G protein αq Subunit is Decreased in Lymphocytes from Patients with Rheumatoid Arthritis and is Correlated with Disease Activity.

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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Interleukin-17 and type 17 helper T cells

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Targeting IL-17 and Th17 cells in rheumatoid arthritis

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In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses

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MAP kinases in the immune response

21 January 2018

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A crucial role for Galphaq/11, but not Galphai/o or Galphas, in gonadotropin-releasing hormone receptor-mediated cell growth inhibition

21 January 2018

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Berberine differentially modulates the activities of ERK, p38 MAPK, and JNK to suppress Th17 and Th1 T cell differentiation in type 1 diabetic mice

21 January 2018

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Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion

21 January 2018

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21 January 2018

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21 January 2018

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Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria

21 January 2018

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Impaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking Galphaq

21 January 2018

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

21 January 2018

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Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor -independent mouse model

21 January 2018

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Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25732870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25732870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25732870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ICB.2015.13

1 reference

29 September 2017

1 reference