The role of CTLA-4 in the regulation and initiation of T-cell responses (Q41332079)

29 September 2017

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title

The role of CTLA-4 in the regulation and initiation of T-cell responses (English)

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29 September 2017

C A Chambers

1

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29 September 2017

M F Krummel

2

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29 September 2017

B Boitel

3

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29 September 2017

A Hurwitz

4

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29 September 2017

T J Sullivan

5

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29 September 2017

S Fournier

6

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29 September 2017

D Cassell

7

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29 September 2017

M Brunner

8

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29 September 2017

J P Allison

9

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29 September 2017

1 October 1996

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29 September 2017

Immunological Reviews

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29 September 2017

153

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29 September 2017

27-46

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CD28-B7 interactions in T-cell activation.

29 September 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Manipulation of costimulatory signals to enhance antitumor T-cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

B70 antigen is a second ligand for CTLA-4 and CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

A new member of the immunoglobulin superfamily--CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

The ups and downs of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

The B7 and CD28 receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Of ITAMs and ITIMs: turning on and off the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

Getting down to specifics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00919.X

10.1111/J.1600-065X.1996.TB00919.X

21 January 2018

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DOI

1 reference

29 September 2017

1 reference