DNA methylation: biology and significance (Q41333669)

29 September 2017

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title

DNA methylation: biology and significance (English)

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29 September 2017

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3

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29 September 2017

Ramsahoye BH

1

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PubMed ID

9012923

29 September 2017

Davies CS

series ordinal

2

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29 September 2017

1 December 1996

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29 September 2017

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29 September 2017

10

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29 September 2017

4

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29 September 2017

249-261

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DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes

29 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Methylation of CpG sequences in eukaryotic DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Eukaryotic DNA methyltransferases--structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Mechanisms of DNA demethylation in chicken embryos. Purification and properties of a 5-methylcytosine-DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA hypomethylation and differentiation in Friend leukemia cell variants

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The 5′-cytosine in CCGG1is methylated in two eukaryotic DNAS and Msp I is sensitive to methylatlon at this site

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The majority of methylated deoxycytidines in human DNA are not in the CpG dinucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

CpNpG methylation in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA methylation and the frequency of CpG in animal DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Analysis of CpG suppression in methylated and nonmethylated species

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

5-Methylcytosine localised in mammalian constitutive heterochromatin.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

New sites of methylcytosine-rich DNA detected on metaphase chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

5-Azadeoxycytidine distinguishes between active and inactive X chromosome condensation

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA methylation specifies chromosomal localization of MeCP2.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Asymmetrical distribution of CpG in an 'average' mammalian gene

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

CG dinucleotide clusters in MHC genes and in 5' demethylated genes

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Unmethylated domains in vertebrate DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

X-chromosome inactivation and cell memory

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Role for DNA methylation in genomic imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Alternative chromatin structure at CpG islands

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Sp1 elements protect a CpG island from de novo methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Unusual methylation pattern of the alpha 2 (l) collagen gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Human muscle carbonic anhydrase: gene structure and DNA methylation patterns in fetal and adult tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Transcriptional unit of the murine Thy-1 gene: different distribution of transcription initiation sites in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The essentials of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Developmental regulation of hypomethylation of delta-crystallin genes in chicken embryo lens cells

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

In contrast to other Xenopus genes the estrogen-inducible vitellogenin genes are expressed when totally methylated

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulated

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP-2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Methylated DNA-binding protein from human placenta recognizes specific methylated sites on several prokaryotic DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Binding sites in mammalian genes and viral gene regulatory regions recognized by methylated DNA-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Position-independent, high-level expression of the human beta-globin gene in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

A major positive regulatory region located far upstream of the human alpha-globin gene locus

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA methylation and the regulation of globin gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

A physiological delay in human fetal hemoglobin switching is associated with specific globin DNA hypomethylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA methylation: a secondary event in globin gene switching?

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Temporal order of chromatin structural changes associated with activation of the major chicken vitellogenin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Loss of methylation activates Xist in somatic but not in embryonic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

1 reference

7 January 2021

Gametic imprinting in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

WT-1 is required for early kidney development

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Mosaic and polymorphic imprinting of the WT1 gene in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Parental imprinting of autosomal mammalian genes

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Genomic imprinting of Mash2, a mouse gene required for trophoblast development

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Identification of a novel paternally expressed gene in the Prader-Willi syndrome region

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The insulin–like growth factor type–2 receptor gene is imprinted in the mouse but not in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Parental imprinting of the Mas protooncogene in mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Allele-specific methylation and expression of an imprinted U2af1-rs1 (SP2) gene

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

De novo methylation and expression of retroviral genomes during mouse embryogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The mutational spectrum of single base-pair substitutions causing human genetic disease: patterns and predictions

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Purification and properties of the human placental uracil DNA glycosylase

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

High frequency mutagenesis by a DNA methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

The 5-methylcytosine content of DNA from human tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Hypomethylation of ras oncogenes in primary human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA methylation decreases in aging but not in immortal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Ras induces a general DNA demethylation activity in mouse embryonal P19 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Model Hereditary Cancers of Man

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Increasing methylation of the calcitonin gene during disease progression in sequential samples from CML patients

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Idiopathic macrocytic anaemia in the aged: molecular and cytogenetic findings

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Estimation of the number of mutations necessary to cause chronic myeloid leukaemia from epidemiological data

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Suppression of intestinal neoplasia by DNA hypomethylation.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Cellular differentiation, cytidine analogs and DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

DNA methylation in the human γδβ-globin locus in erythroid and nonerythroid tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Clinical, hematologic and biosynthetic studies in sickle cell-β°-thalassemia: A comparison with sickle cell anemia

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Natural history of sickle cell anemia in Saudi Arabs. A study of 270 subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Hb F production in stressed erythropoiesis: observations and kinetic models.

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Brief report: treatment with azacitidine of patients with end-stage beta-thalassemia

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

5-Azacytidine. A new anticancer drug with effectiveness in acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

Effect of schedule on activity and toxicity of 5-azacytidine in acute leukemia: A southwest oncology group study

1 reference

https://api.crossref.org/works/10.1016%2FS0268-960X%2896%2990009-0

7 January 2021

10.1016/S0268-960X(96)90009-0

Identifiers

DOI

1 reference

29 September 2017

1 reference

PubMed ID

9012923