The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome (Q41351026)

29 September 2017

title

The transduction pattern of IL-12-encoding lentiviral vectors shapes the immunological outcome (English)

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29 September 2017

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1

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2 June 2020

Katrijn Broos

2

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2 June 2020

Geert Raes

5

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2 June 2020

Karine Breckpot

8

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2 June 2020

7

Kris Thielemans

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2 June 2020

author name string

David Escors

3

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2 June 2020

Carlo Heirman

4

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2 June 2020

Patrick De Baetselier

6

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2 June 2020

language of work or name

English

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publication date

17 September 2015

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European Journal of Immunology

29 September 2017

published in

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2 June 2020

volume

45

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2 June 2020

issue

12

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2 June 2020

page(s)

3351-3361

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Getting by with a little help from the right CD4(+) T cells.

2 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Immune adjuvants as critical guides directing immunity triggered by therapeutic cancer vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Boosting the MHC Class II-Restricted Tumor Antigen Presentation to CD4+ T Helper Cells: A Critical Issue for Triggering Protective Immunity and Re-Orienting the Tumor Microenvironment Toward an Anti-Tumor State

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Lentiviral vectors in gene therapy: their current status and future potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Development of the Nanobody display technology to target lentiviral vectors to antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Targeting of human antigen-presenting cell subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Immunogenicity of targeted lentivectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Immunization of mice with lentiviral vectors targeted to MHC class II+ cells is due to preferential transduction of dendritic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

IL-12 family cytokines: immunological playmakers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Interleukin-12: biological properties and clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Reversing tumor immune suppression with intratumoral IL-12: activation of tumor-associated T effector/memory cells, induction of T suppressor apoptosis, and infiltration of CD8+ T effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

The CD8+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Interleukin 12: still a promising candidate for tumor immunotherapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: Evidence for IL-12 intracrine activity in DC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

IL-12 immunotherapy of murine leukaemia: comparison of systemic versus gene modified cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Principal role of IL-12p40 in the decreased Th1 and Th17 responses driven by dendritic cells of mice lacking IL-12 and IL-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Local secretion of IL-12 augments the therapeutic impact of dendritic cell-tumor cell fusion vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

The role of protein modifications of T-bet in cytokine production and differentiation of T helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic Semliki Forest virus encoding IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

IL-12 enhances CTL synapse formation and induces self-reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Intratumoral delivery of IL-12 gene by polyvinyl polymeric vector system to murine renal and colon carcinoma results in potent antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Integrase-defective lentiviral vectors encoding cytokines induce differentiation of human dendritic cells and stimulate multivalent immune responses in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Cell-specific targeting of lentiviral vectors mediated by fusion proteins derived from Sindbis virus, vesicular stomatitis virus, or avian sarcoma/leukosis virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Induction of Influenza Matrix Protein 1 and MelanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

Interleukin-12 inhibits the survival of human colon cancer stem cells in vitro and their tumor initiating capacity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

7 January 2021

CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

7 January 2021

Activation of Immature Monocyte-Derived Dendritic Cells After Transduction with High Doses of Lentiviral Vectors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

7 January 2021

Exogenous recombinant human IL-12 augments MHC class I antigen expression on human cancer cells in vitro

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

7 January 2021

Human CD4+ T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

7 January 2021

Efficient genetic modification of murine dendritic cells by electroporation with mRNA

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545559

7 January 2021

Identifiers

DOI

10.1002/EJI.201545559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26377033%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference