Statins inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-β-independent process. (Q41369308)

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18 January 2020

title

Statins inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-β-independent process (English)

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18 January 2020

4

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18 January 2020

Juan Rodriguez-Vita

6

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18 January 2020

Marta Ruiz-Ortega

10

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18 January 2020

Marta Ruiz-Ortega

11

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18 January 2020

author name string

Raúl Rodrigues Díez

1

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18 January 2020

Raquel Rodrigues-Díez

2

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18 January 2020

Carolina Lavoz

3

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18 January 2020

Esther Civantos

5

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18 January 2020

Sergio Mezzano

7

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18 January 2020

Jesús Egido

9

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18 January 2020

Alberto Ortiz

8

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18 January 2020

language of work or name

English

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publication date

30 November 2010

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18 January 2020

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18 January 2020

volume

5

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18 January 2020

issue

11

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18 January 2020

page(s)

e14145

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Creative Commons Attribution 4.0 International

18 January 2020

copyright license

start time

30 November 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Essential role of Smad3 in angiotensin II-induced vascular fibrosis

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Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis.

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Pharmacological inhibition and genetic deficiency of plasminogen activator inhibitor-1 attenuates angiotensin II/salt-induced aortic remodeling.

1 October 2017

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TGF-beta signaling and the fibrotic response

1 October 2017

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Epithelial-mesenchymal transition and its implications for fibrosis

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ANG II increases TIMP-1 expression in rat aortic smooth muscle cells in vivo

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Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells.

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Simvastatin abates development of renal fibrosis in experimental renovascular disease

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19 August 2018

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12 December 2020

HMG-CoA Reductase Inhibitors Decrease Angiotensin II–Induced Vascular Fibrosis

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12 December 2020

Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation

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12 December 2020

Smad protein and TGF-beta signaling in vascular smooth muscle cells

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12 December 2020

Angiotensin II type I receptor antagonist inhibits the gene expression of transforming growth factor-beta 1 and extracellular matrix in cardiac and vascular tissues of hypertensive rats

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12 December 2020

10.1371/JOURNAL.PONE.0014145

Identifiers

DOI

1 reference

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18 January 2020

0 references

1 reference

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18 January 2020

PubMed publication ID

21152444

1 reference