Impact of alpha-hydroxy-propanodeoxyguanine adducts on DNA duplex energetics: opposite base modulation and implications for mutagenicity and genotoxicity. (Q41371500)

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scientific article published on April 2010

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English	Impact of alpha-hydroxy-propanodeoxyguanine adducts on DNA duplex energetics: opposite base modulation and implications for mutagenicity and genotoxicity.	scientific article published on April 2010

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scholarly article

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12 February 2020

Impact of alpha-hydroxy-propanodeoxyguanine adducts on DNA duplex energetics: opposite base modulation and implications for mutagenicity and genotoxicity (English)

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12 February 2020

Conceicao Minetti

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12 February 2020

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12 February 2020

author name string

Francis Johnson

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12 February 2020

Charles R Iden

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12 February 2020

Kenneth J Breslauer

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12 February 2020

publication date

1 April 2010

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12 February 2020

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12 February 2020

93

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12 February 2020

4

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12 February 2020

370-382

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12 February 2020

Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers

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1 October 2017

Solution structure of DNA containing -OH-PdG: the mutagenic adduct produced by acrolein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

Mutagenicity and sequence specificity of acrolein-DNA adducts

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

UNAFold: software for nucleic acid folding and hybridization

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1 October 2017

Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

Solution structure of duplex DNA containing the mutagenic lesion 1,N(2)-etheno-2'-deoxyguanine

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease

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1 October 2017

DINAMelt web server for nucleic acid melting prediction

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1 October 2017

Mutagenesis by acrolein-derived propanodeoxyguanosine adducts in human cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

NMR characterization of clustered bistrand abasic site lesions: effect of orientation on their solution structure

1 reference

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1 October 2017

Evaluation of the mutagenic potential of the principal DNA adduct of acrolein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

NMR characterization of a DNA duplex containing the major acrolein-derived deoxyguanosine adduct gamma -OH-1,-N2-propano-2'-deoxyguanosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

Effects of 3,N4-ethenodeoxycytidine on duplex stability and energetics.

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1 October 2017

A more unified picture for the thermodynamics of nucleic acid duplex melting: a characterization by calorimetric and volumetric techniques

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1 October 2017

A quantitative method for evaluating the stabilities of nucleic acids

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

NMR solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite thymidine: comparison with the duplex containing deoxyadenosine opposite the adduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

DNA lesions. A thermodynamic perspective

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1 October 2017

Mutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

Calculating thermodynamic data for transitions of any molecularity from equilibrium melting curves

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

1 October 2017

Regioisomeric synthesis and characteristics of the alpha-hydroxy-1,N(2)-propanodeoxyguanosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

11 June 2018

Genotoxic mechanism for the major acrolein-derived deoxyguanosine adduct in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

11 June 2018

Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule".

1 reference

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11 June 2018

Formation of cyclic 1,N2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

11 June 2018

Influence of an exocyclic guanine adduct on the thermal stability, conformation, and melting thermodynamics of a DNA duplex

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

11 June 2018

The lipid peroxidation product 4-hydroxynonenal is a potent inducer of the SOS response

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11 June 2018

Acrolein: excessive cytotoxicity or potent mutagenicity?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

19 August 2018

Interstrand DNA cross-links induced by alpha,beta-unsaturated aldehydes derived from lipid peroxidation and environmental sources.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

19 August 2018

Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

19 August 2018

Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived alpha-HOPdG and gamma-HOPdG regioisomeric deoxyguanosine adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

19 August 2018

Synthesis of the minor acrolein adducts of 2′-deoxyguanosine and their generation in oligomeric DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891022

19 August 2018

DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine

1 reference

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19 August 2018

Influence of flanking sequence context on the mutagenicity of acetylaminofluorene-derived DNA adducts in mammalian cells

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19 August 2018

Responses to the major acrolein-derived deoxyguanosine adduct in Escherichia coli

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19 August 2018

Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro

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19 August 2018

Influence of the oxidatively damaged adduct 8-oxodeoxyguanosine on the conformation, energetics, and thermodynamic stability of a DNA duplex.

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19 August 2018

The impact of a bistrand abasic lesion on DNA duplex properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

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Rate of incision of N-acetyl-2-aminofluorene and N-2-aminofluorene adducts by UvrABC nuclease is adduct- and sequence-specific: comparison of the rates of UvrABC nuclease incision and protein-DNA complex formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nearest neighbor thermodynamic parameters for internal G.A mismatches in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermodynamic consequences of an abasic lesion in duplex DNA are strongly dependent on base sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The impact of an exocyclic cytosine adduct on DNA duplex properties: significant thermodynamic consequences despite modest lesion-induced structural alterations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postsynthetic generation of a major acrolein adduct of 2'-deoxyguanosine in oligomeric DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of nucleosides and oligonucleotides containing adducts of acrolein and vinyl chloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR studies of exocyclic 1,N2-propanodeoxyguanosine adducts (X) opposite purines in DNA duplexes: protonated X(syn).A(anti) pairing (acidic pH) and X(syn).G(anti) pairing (neutral pH) at the lesion site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMR studies of an exocyclic 1,N2-propanodeoxyguanosine adduct (X) located opposite deoxyadenosine (A) in DNA duplexes at basic pH: simultaneous partial intercalation of X and A between stacked bases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural features of an exocyclic adduct positioned opposite an abasic site in a DNA duplex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19937758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/BIP.21355

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12 February 2020

PMC publication ID

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12 February 2020

PubMed publication ID

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12 February 2020

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