Non-insulin-dependent diabetes mellitus--a collision between thrifty genes and an affluent society (Q41386996)

30 September 2017

1 reference

title

Non-insulin-dependent diabetes mellitus--a collision between thrifty genes and an affluent society (English)

1 reference

30 September 2017

2

T Tuomi

1 reference

30 September 2017

L C Groop

1

1 reference

PubMed ID

9073323

30 September 2017

language of work or name

English

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publication date

1 February 1997

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30 September 2017

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30 September 2017

29

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30 September 2017

37-53

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30 September 2017

1

1 reference

Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland

30 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Importance of maternal history of non-insulin dependent diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Metabolic consequences of a family history of NIDDM (the Botnia study): evidence for sex-specific parental effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Mitochondria and diabetes. Genetic, biochemical, and clinical implications of the cellular energy circuit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Maternally inherited diabetes and deafness: a new diabetes subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetics and physiology of the myotonic muscle disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Mutations in insulin-receptor gene in insulin-resistant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Acute and chronic effects of hyperglycaemia on glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM. Evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Impaired insulin-mediated skeletal muscle blood flow in patients with NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Abnormal activation of glycogen synthesis in fibroblasts from NIDDM subjects. Evidence for an abnormality specific to glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Mechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

No reduction in total hepatic glucose output by inhibition of gluconeogenesis with ethanol in NIDDM patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin resistance in type 2 (non-insulin-dependent) diabetic patients with hypertriglyceridaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Does intra-abdominal adipose tissue in black men determine whether NIDDM is insulin-resistant or insulin-sensitive?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin resistance and abnormal albumin excretion in non-diabetic first-degree relatives of patients with NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Reduced rate of energy expenditure as a risk factor for body-weight gain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Obesity genes: beneficial effects in heterozygous mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A pathogenic role of visceral fat beta 3-adrenoceptors in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Tissue distribution of beta 3-adrenergic receptor mRNA in man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Carbohydrate and lipid metabolism of skeletal muscle in type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin action and substrate competition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin resistance and insulin deficiency in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Islet cell antibodies identify latent type I diabetes in patients aged 35-75 years at diagnosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic parents.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

The influence of body fat distribution on the incidence of diabetes mellitus. 13.5 years of follow-up of the participants in the study of men born in 1913.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

The diastrophic dysplasia gene encodes a novel sulfate transporter: positional cloning by fine-structure linkage disequilibrium mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Identification of trinucleotide repeat-containing genes in human pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Role of IRS-2 in insulin and cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Kinetics of insulin action in vivo. Identification of rate-limiting steps

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Facilitative glucose transporters: regulatory mechanisms and dysregulation in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Human hexokinase II mRNA and gene structure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Isolation and characterization of the human muscle glycogen synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Association between polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Description of a second microsatellite marker and linkage analysis of the muscle glycogen synthase locus in familial NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Linkage analysis of 19 candidate regions for insulin resistance in familial NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A question of balance: ups and downs of mucosal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

The role of neuropeptide Y in the antiobesity action of the obese gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Molecular characterization of the human beta 3-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Association of Trp64Arg mutation of the ?3-adrenergic-receptor with NIDDM and body weight gain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

The expression of TNF alpha by human muscle. Relationship to insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A role for glucagon-like peptide-1 in the central regulation of feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetic susceptibility to non-insulin dependent diabetes mellitus and glucose intolerance are located in HLA region

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

HLA-associated susceptibility to type 2 (non-insulin-dependent) diabetes mellitus: the Wadena City Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A genome-wide search for human type 1 diabetes susceptibility genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Polymorphism in the 5′ Flanking Region of the Human Insulin Gene: A Genetic Marker for Non-Insulin-Dependent Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Linkage studies in NIDDM with markers near the sulphonylurea receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

No evidence for mutations in a putative beta-cell ATP-sensitive K+ channel subunit in MODY, NIDDM, or GDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A missense mutation in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A mutation in the glucagon receptor gene (Gly40Ser): heterogeneity in the association with diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetic analysis of NIDDM. The study of quantitative traits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Evidence for linkage of postchallenge insulin levels with intestinal fatty acid-binding protein (FABP2) in Mexican-Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Chromosome 4q locus associated with insulin resistance in Pima Indians. Studies in three European NIDDM populations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Evidence for linkage between a region on chromosome 1p and the acute insulin response in Pima Indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Genetic dissection of complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Is there an excess in maternal transmission of NIDDM?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

Segregation analysis of NIDDM in Caucasian families

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853899708998742

10.3109/07853899708998742

21 January 2018

Identifiers

DOI

1 reference

30 September 2017

1 reference

PubMed ID

9073323