Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase (Q41437655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945234%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

title

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase (English)

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29 October 2019

1

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29 October 2019

author name string

E J Foulstone

2

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29 October 2019

S W Young

3

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29 October 2019

J M Tavaré

4

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29 October 2019

C G Proud

5

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29 October 2019

language of work or name

English

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publication date

1 October 1994

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29 October 2019

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29 October 2019

volume

303 ( Pt 1)

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29 October 2019

page(s)

15-20

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

29 October 2019

cites work

1 reference

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Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggy

1 October 2017

1 reference

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The insulin signaling system

1 October 2017

1 reference

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

1 October 2017

1 reference

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The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.

1 October 2017

1 reference

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Identification of novel phosphorylation sites in the beta-subunit of translation initiation factor eIF-2

1 October 2017

1 reference

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Activation of Raf as a result of recruitment to the plasma membrane

1 October 2017

1 reference

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Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase

1 October 2017

1 reference

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Molecular cloning and expression of glycogen synthase kinase-3/factor A

1 October 2017

1 reference

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Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6.

1 October 2017

1 reference

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Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases

1 October 2017

1 reference

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Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1 October 2017

1 reference

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Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

A common denominator linking glycogen metabolism, nuclear oncogenes and development

1 October 2017

1 reference

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Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6.

1 October 2017

1 reference

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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

1 October 2017

1 reference

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Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Glycogen synthase kinase-3: functions in oncogenesis and development

1 October 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Differential Raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Purification and characterisation of the insulin-stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Involvement of p21ras in activation of extracellular signal-regulated kinase 2.

11 June 2018

1 reference

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Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

11 June 2018

1 reference

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Identification of multifunctional ATP-citrate lyase kinase as the alpha-isoform of glycogen synthase kinase-3

11 June 2018

1 reference

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Characterization of insulin-stimulated protein serine/threonine kinases in CHO cells expressing human insulin receptors with point and deletion mutations

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes

11 June 2018

1 reference

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

Dissociation of pp70 ribosomal protein S6 kinase from insulin-stimulated glucose transport in 3T3-L1 adipocytes.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1137549

ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. II. Purification of the activating factor and its characterization as a bifunctional protein also displaying synthase kinase activity

19 August 2018

1 reference

12 December 2020

Purification of Glycogen Synthase Kinase 3 from Rabbit Skeletal Muscle.. Copurification with the Activating Factor (FA)of the (Mg-ATP) Dependent Protein Phosphatase

1 reference

12 December 2020

Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo

1 reference

12 December 2020

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

12 December 2020

Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669

1 reference

12 December 2020

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

1 reference

12 December 2020

The pathway to signal achievement

1 reference

12 December 2020

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

1 reference

12 December 2020

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters

1 reference

12 December 2020

The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ3030015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945234%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7945234%20AND%20SRC:MED&resulttype=core&format=json

29 October 2019

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