Targeted gene disruption: applications in neurobiology (Q41449975)

30 September 2017

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title

Targeted gene disruption: applications in neurobiology (English)

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30 September 2017

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van der Neut R

1

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30 September 2017

1 January 1997

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Journal of Neuroscience Methods

30 September 2017

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30 September 2017

71

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30 September 2017

19-27

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30 September 2017

1

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Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.

30 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

A novel role for site-specific recombination in maintenance of bacterial replicons

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Embryonic stem cells express neuronal properties in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Excision of specific DNA-sequences from integrated retroviral vectors via site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

GFAP promoter directs astrocyte-specific expression in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Neural crest cell formation and migration in the developing embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Construction of a new universal vector for insertional mutagenesis by homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Death before birth: clues from gene knockouts and mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Quantitative estimation of chimerism in mice using microsatellite markers

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Consequences of lack of beta 1 integrin gene expression in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Synapse formation and establishment of neuronal polarity by P19 embryonic carcinoma cells and embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Mice devoid of the glial fibrillary acidic protein develop normally and are susceptible to scrapie prions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Transcriptional activation by tetracyclines in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

The proximal region of the MBP gene promoter is sufficient to induce oligodendroglial-specific expression in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Site-specific recombination by the bacteriophage P1 lox-Cre system. Cre-mediated synapsis of two lox sites

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Efficiency of insertion versus replacement vector targeting varies at different chromosomal loci

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Mouse knockouts rule OK

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

The role of the loxP spacer region in P1 site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Alpha 1 beta 1 integrin on neural crest cells recognizes some laminin substrata in a Ca(2+)-independent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Inhibition of neural crest cell attachment by integrin antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Neural crest cell interactions with laminin: structural requirements and localization of the binding site for alpha 1 beta 1 integrin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Studies on the influence of cytosine methylation on DNA recombination and end-joining in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Disruption of the CNTF gene results in motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Expression of the rat calmodulin gene II in the central nervous system: a 294-base promoter and 68-base leader segment mediates neuron-specific gene expression in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

P0 promoter directs expression of reporter and toxin genes to Schwann cells of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Multiple essential functions of neuregulin in development

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

The 5'-flanking region of the human dopamine beta-hydroxylase gene promotes neuron subtype-specific gene expression in the central nervous system of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

The human synapsin II gene promoter. Possible role for the transcription factor zif268/egr-1, polyoma enhancer activator 3, and AP2.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Recognition and alignment of homologous DNA sequences between minichromosomes and single-stranded DNA promoted by RecA protein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Knockout mouse fault lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Efficient regulation of gene expression by adenovirus vector-mediated delivery of the CRE recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

The human D1A dopamine receptor gene promoter directs expression of a reporter gene to the central nervous system in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Spatial and temporal regulation of the rat calmodulin gene III directed by a 877-base promoter and 103-base leader segment in the mature and embryonal central nervous system of transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Gene Targeting in ES Cells

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https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Multiple promoters direct tissue-specific expression of the rat BDNF gene

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

The 5' flanking region of the serotonin 2 receptor gene directs brain specific expression in transgenic animals

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

Targeting of the creatine kinase M gene in embryonic stem cells using isogenic and nonisogenic vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

A novel ES cell line, TT2, with high germline-differentiating potency

1 reference

https://api.crossref.org/works/10.1016%2FS0165-0270%2896%2900123-9

7 January 2021

10.1016/S0165-0270(96)00123-9

Identifiers

DOI

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30 September 2017

1 reference

PubMed ID

9125372