Defining a role for c-Myc in breast tumorigenesis. (Q41481874)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9164674%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

review article

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title

Defining a role for c-Myc in breast tumorigenesis (English)

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3 November 2019

1

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3 November 2019

author name string

R B Dickson

series ordinal

2

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3 November 2019

language of work or name

English

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publication date

1 May 1997

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9164674%20AND%20SRC:MED&resulttype=core&format=json

Breast Cancer Research and Treatment

3 November 2019

published in

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3 November 2019

volume

44

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3 November 2019

issue

1

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3 November 2019

page(s)

1-22

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https://scigraph.springernature.com/pub.10.1023/a:1005858611585

3 November 2019

exact match

0 references

cites work

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A link between c-Myc-mediated transcriptional repression and neoplastic transformation

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Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death

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Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

21 January 2018

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An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3

21 January 2018

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A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

21 January 2018

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Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

21 January 2018

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An E-box-mediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants

21 January 2018

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Cdc25 cell-cycle phosphatase as a target of c-myc

21 January 2018

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Cell cycle regulation of the c-Myc transcriptional activation domain

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Binding and suppression of the Myc transcriptional activation domain by p107.

21 January 2018

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Apoptosis and the cell cycle.

21 January 2018

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Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

21 January 2018

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Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

21 January 2018

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Yin-yang 1 activates the c-myc promoter

21 January 2018

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Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

21 January 2018

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Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells.

21 January 2018

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c-fos, c-jun and c-myc expressions are not growth rate limiting for the human MCF-7 breast cancer cells

21 January 2018

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Suppression of the EGF-dependent induction of c-myc proto-oncogene expression by transforming growth factor beta in a human breast carcinoma cell line.

21 January 2018

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Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression

21 January 2018

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Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes

21 January 2018

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Differential regulation of c-myc by progestins and antiestrogens in T-47D human breast cancer cells

21 January 2018

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Use of tamoxifen for breast cancer: twenty-eight years later

21 January 2018

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Role of c-myc in tamoxifen-induced apoptosis estrogen-independent breast cancer cells

21 January 2018

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Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in MCF-7 breast cancer cells

21 January 2018

1 reference

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Growth arrest and non-apoptotic cell death associated with the suppression of c-myc expression in MCF-7 breast tumor cells following acute exposure to doxorubicin

21 January 2018

1 reference

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Influence of amsacrine (m-AMSA) on bulk and gene-specific DNA damage and c-myc expression in MCF-7 breast tumor cells

21 January 2018

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Transcriptional down-regulation of c-myc expression in the MCF-7 breast tumor cell line by the topoisomerase II inhibitor, VM-26.

21 January 2018

1 reference

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Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression

21 January 2018

1 reference

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A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain

21 January 2018

1 reference

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Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas

21 January 2018

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Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease

21 January 2018

1 reference

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c-erbB-2/c-erbA co-amplification indicative of lymph node metastasis, and c-myc amplification of high tumour grade, in human breast carcinoma

21 January 2018

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Cathepsin D assay in primary breast cancer and lymph nodes: Relationship with c-myc, c-erb-B-2 and int-2 oncogene amplification and node invasiveness

21 January 2018

1 reference

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Prevalence of amplification of the oncogenes c-myc, HER2/neu, and int-2 in one thousand human breast tumours: correlation with steroid receptors

21 January 2018

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c-myc amplification is an independent prognostic factor in postmenopausal breast cancer

21 January 2018

1 reference

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Relationship of c-myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis

21 January 2018

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Mutations in human breast cancer: an overview

21 January 2018

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Oncogene protein co-expression. Value of Ha-ras, c-myc, c-fos, and p53 as prognostic discriminants for breast carcinoma

21 January 2018

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

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Apoptotic cell death induced by c-myc is inhibited by bcl-2.

21 January 2018

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Cooperative interaction between c-myc and bcl-2 proto-oncogenes

21 January 2018

1 reference

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

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Myc-mediated apoptosis is blocked by ectopic expression of Bcl-2

21 January 2018

1 reference

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Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor

21 January 2018

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Potentiation of growth factor activity by exogenous c-myc expression.

21 January 2018

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Modulation of transforming growth factor type beta action by activated ras and c-myc

21 January 2018

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Stromal influences on transformation of human mammary epithelial cells overexpressing c-myc and SV40T.

21 January 2018

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V-MycAlters the Response of a Cloned Mouse Mammary Epithelial Cell Line to Lactogenic Hormones

21 January 2018

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Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Effects of c-myc expression on cell cycle progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Differential modulation of cyclin gene expression by MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Repression of cyclin D1: a novel function of MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Participation of cyclin A in Myc-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Rescue of defective mitogenic signaling by D-type cyclins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

c-Myc cooperates with activated Ras to induce the cdc2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Tumor suppression and inhibition of aneuploid cell accumulation in human brain tumor cells by ectopic overexpression of the cyclin-dependent kinase inhibitor p27KIP1.

21 January 2018

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Genomic instability in MycER-activated Rat1A-MycER cells

21 January 2018

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Induction of apoptosis by tumor suppressor genes and oncogenes

21 January 2018

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Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1005858611585

Premature p34cdc2 activation required for apoptosis.

21 January 2018

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Activation of cyclin A-dependent protein kinases during apoptosis

21 January 2018

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https://api.crossref.org/works/10.1023%2FA%3A1005858611585

A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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The functional basis of c-myc and bcl-2 complementation during multistep lymphomagenesis in vivo.

21 January 2018

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c-myc and bcl-2 modulate p53 function by altering p53 subcellular trafficking during the cell cycle

21 January 2018

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The tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

21 January 2018

Beating a path to Myc

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

21 January 2018

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Function of the c-Myc oncoprotein

21 January 2018

1 reference

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7 January 2021

Interaction of c-Myc with the pRb-related protein p107 results in inhibition of c-Myc-mediated transactivation

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathway

1 reference

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7 January 2021

Estradiol stimulates c-myc proto-oncogene expression in normal human breast epithelial cells in culture

1 reference

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7 January 2021

Pharmacologic and biologic properties of droloxifene, a new antiestrogen.

1 reference

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7 January 2021

Inhibition of growth-factor-activated proliferation by anti-estrogens and effects on early gene expression of MCF-7 cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Antiestrogens inhibit the mitogenic effect of growth factors on breast cancer cells in the total absence of estrogens

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https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Analysis of human breast cancer nuclear proteins binding to the promoter elements of the c-myc gene

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7 January 2021

C-myc gene chromatin of estrogen receptor positive and negative breast cancer cells

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7 January 2021

In Vivo Amplification and Rearrangement of c-myc Oncogene in Human Breast Tumors

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7 January 2021

Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas

1 reference

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7 January 2021

High cell kinetics is associated with amplification of the int-2, bcl-1, myc and erbB-2 proto-oncogenes and loss of heterozygosity at the DF3 locus in primary breast cancers

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Prognostic value of erb-B2 and myc amplification in breast cancer imprints

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Heterogeneity of c-myc expression in histologically similar infiltrating ductal carcinomas of the breast

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Transcriptional activation of the c-myc proto-oncogene in murine keratinocytes enhances the response to epidermal growth factor

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

The MYC protein activates transcription of the alpha-prothymosin gene.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Human mammary epithelial cells in culture: differentiation and transformation.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021

Role for Bcl-xL in the regulation of apoptosis by EGF and TGF beta 1 in c-myc overexpressing mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1005858611585

7 January 2021