Oncogenic mechanisms mediated by DNA methylation (Q41492393)

1 October 2017

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title

Oncogenic mechanisms mediated by DNA methylation (English)

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1 October 2017

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P W Laird

1

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1 October 2017

1 May 1997

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Trends in Molecular Medicine

1 October 2017

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1 October 2017

3

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1 October 2017

5

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1 October 2017

223-229

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901019-8

1 October 2017

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Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP

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Cancer development: the rise of epigenetics

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Cellular epigenetics and the origin of cancer

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Dependence of transcriptional repression on CpG methylation density

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The impact of 5'-CG-3' methylation on the activity of different eukaryotic promoters: a comparative study

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The mutational spectrum of single base-pair substitutions causing human genetic disease: patterns and predictions

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DNA methyltransferases

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901019-8

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DNA demethylation in vitro: involvement of RNA.

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DNA methylation and cancer

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Cancer. Exploring the bowels of DNA methylation

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The role of DNA methylation in cancer genetic and epigenetics

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Alterations in DNA methylation may play a variety of roles in carcinogenesis

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901019-8

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5-Methylcytosine content of nuclear DNA during chemical hepatocarcinogenesis and in carcinomas which result

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The 5-methylcytosine content of DNA from human tumors

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

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Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

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Suppression of intestinal neoplasia by DNA hypomethylation.

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

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5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

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The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901019-8

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High frequency mutagenesis by a DNA methyltransferase

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901019-8

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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https://api.crossref.org/works/10.1016%2FS1357-4310%2897%2901019-8

7 January 2021

10.1016/S1357-4310(97)01019-8

Identifiers

DOI

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1 October 2017

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PubMed ID

9176885