Amyloid precursor protein, copper and Alzheimer's disease (Q41495946)

1 October 2017

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title

Amyloid precursor protein, copper and Alzheimer's disease (English)

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1 October 2017

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Multhaup G

1

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1 October 2017

publication date

1 January 1997

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Biomedicine and Pharmacotherapy

1 October 2017

published in

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1 October 2017

volume

51

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1 October 2017

issue

3

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1 October 2017

page(s)

105-111

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 October 2017

cites work

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7 January 2021

Amyloid beta-protein and the genetics of Alzheimer's disease

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7 January 2021

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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7 January 2021

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

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7 January 2021

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

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7 January 2021

Mis-sense mutation Val&rarr;Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease

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7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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7 January 2021

Release of excess amyloid beta protein from a mutant amyloid beta protein precursor.

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7 January 2021

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

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7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

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7 January 2021

Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome

1 reference

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7 January 2021

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

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7 January 2021

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

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7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

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7 January 2021

Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

1 reference

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7 January 2021

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

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7 January 2021

Production of the Alzheimer amyloid beta protein by normal proteolytic processing

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7 January 2021

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

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7 January 2021

β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

1 reference

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7 January 2021

beta-Amyloid neurotoxicity in human cortical culture is not mediated by excitotoxins

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7 January 2021

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Radical AGEing in Alzheimer's disease

1 reference

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7 January 2021

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

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7 January 2021

Mechanisms of neuronal degeneration in Alzheimer's disease

1 reference

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7 January 2021

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Aluminum, iron, and zinc ions promote aggregation of physiological concentrations of beta-amyloid peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Identification and regulation of the high affinity binding site of the Alzheimer's disease amyloid protein precursor (APP) to glycosaminoglycans

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP).

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Purification of factor XIa inhibitor from human platelets

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https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Zinc (II) selectively enhances the inhibition of coagulation factor XIa by protease nexin-2/amyloid beta-protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Intracellular routing of human amyloid protein precursor: Axonal delivery followed by transport to the dendrites

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

The beta A4 amyloid precursor protein binding to copper.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Strategies of antioxidant defense

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Hydroperoxide metabolism in mammalian organs

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Superoxide dismutases

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Role of free radicals and catalytic metal ions in human disease: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Superoxide anion permeability of phospholipid membranes and chloroplast thylakoids

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https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Biologically relevant metal ion-dependent hydroxyl radical generation. An update

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Protein oxidation and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Oxidative damage in Alzheimer's.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Macroxyproteinase (M.O.P.): a 670 kDa proteinase complex that degrades oxidatively denatured proteins in red blood cells.

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https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Mitochondria contain a proteolytic system which can recognize and degrade oxidatively-denatured proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Familial motor neuron disease. Evidence for at least three different types

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide. Inactivation of the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Zinc and Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Cerebrospinal fluid trace element content in dementia: clinical, radiologic, and pathologic correlations.

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Generation of beta A4 from the amyloid protein precursor and fragments thereof

1 reference

https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

Cultured GABA-immunoreactive neurons are resistant to toxicity induced by beta-amyloid

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https://api.crossref.org/works/10.1016%2FS0753-3322%2897%2986907-7

7 January 2021

10.1016/S0753-3322(97)86907-7

Identifiers

DOI

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1 October 2017

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