Simultaneous induction of stimulatory and inhibitory signals by PDGF. (Q41553992)

3 October 2017

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title

Simultaneous induction of stimulatory and inhibitory signals by PDGF. (English)

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3 October 2017

Heldin CH

1

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PubMed ID

9247114

3 October 2017

language of work or name

English

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publication date

1 June 1997

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3 October 2017

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3 October 2017

410

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3 October 2017

1

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3 October 2017

17-21

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Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

3 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Platelet-derived growth factor BB for the treatment of chronic pressure ulcers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Ligand-induced dimerization of growth factor receptors: variations on the theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Protein modules and signalling networks

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Cytokine receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

The chemotactic response to PDGF-BB: evidence of a role for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Identification of a putative Syp substrate, the PDGF beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900318-9

10.1016/S0014-5793(97)00318-9

21 January 2018

Identifiers

DOI

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3 October 2017

1 reference

PubMed ID

9247114