Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? (Q41557551)

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scientific article published on December 2010

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English	Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?	scientific article published on December 2010

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scholarly article

1 reference

Europe PubMed Central

3 October 2017

Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? (English)

1 reference

Europe PubMed Central

3 October 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

allergic asthma

1 reference

based on heuristic

inferred from title

Jennifer M Bratt

2

0 references

author name string

Amir A Zeki

1

1 reference

Europe PubMed Central

3 October 2017

Jennifer M Bratt

2

1 reference

Europe PubMed Central

3 October 2017

Michelle Rabowsky

3

1 reference

Europe PubMed Central

3 October 2017

Jerold A Last

4

1 reference

Europe PubMed Central

3 October 2017

Nicholas J Kenyon

5

1 reference

Europe PubMed Central

3 October 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 December 2010

1 reference

Europe PubMed Central

3 October 2017

Translational Research

1 reference

Europe PubMed Central

3 October 2017

156

1 reference

Europe PubMed Central

3 October 2017

6

1 reference

Europe PubMed Central

3 October 2017

335-349

1 reference

Europe PubMed Central

3 October 2017

The effects of current therapies on airway remodeling in asthma and new possibilities for treatment and prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

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Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2.

1 reference

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6 June 2018

Arginase inhibition in airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.

1 reference

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Targeting the airway smooth muscle for asthma treatment

1 reference

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6 June 2018

Arginase: a key enzyme in the pathophysiology of allergic asthma opening novel therapeutic perspectives

1 reference

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Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond

1 reference

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Advances in mucous cell metaplasia: a plug for mucus as a therapeutic focus in chronic airway disease

1 reference

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Statins in COPD: a systematic review

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6 June 2018

Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.

1 reference

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Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences

1 reference

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Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients.

1 reference

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Diabetes-induced coronary vascular dysfunction involves increased arginase activity

1 reference

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Statin use reduces decline in lung function: VA Normative Aging Study

1 reference

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The regulatory role of TGF-beta in airway remodeling in asthma

1 reference

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6 June 2018

Potential therapeutic role for statins in respiratory disease

1 reference

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Induction of arginase I transcription by IL-4 requires a composite DNA response element for STAT6 and C/EBPbeta

1 reference

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Pirfenidone inhibits lung allograft fibrosis through L-arginine-arginase pathway

1 reference

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6 June 2018

Pleiotropic effects of statins

1 reference

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Interleukin-6 and mevastatin regulate plasminogen activator inhibitor-1 through CCAAT/enhancer-binding protein-delta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

Macrophage arginase regulation by CCAAT/enhancer-binding protein beta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

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Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells

1 reference

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Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

Beyond lipid-lowering: effects of statins on endothelial nitric oxide

1 reference

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6 June 2018

Remodeling in asthma and chronic obstructive lung disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

Pravastatin attenuates lower torso ischaemia-reperfusion-induced lung injury by upregulating constitutive endothelial nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

Inhibition of small G proteins of the rho family by statins or clostridium difficile toxin B enhances cytokine-mediated induction of NO synthase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

IL-4 and IL-13 upregulate arginase I expression by cAMP and JAK/STAT6 pathways in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

An improved murine model of asthma: selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

6 June 2018

Simvastatin attenuates experimental small airway remodelling in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

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Effect of rosuvastatin on cardiac remodeling, function, and progression to heart failure in hypertensive heart with established left ventricular hypertrophy.

1 reference

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Mepacrine inhibits subepithelial fibrosis by reducing the expression of arginase and TGF-beta1 in an extended subacute mouse model of allergic asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

19 August 2018

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

19 August 2018

Simvastatin attenuates bleomycin-induced pulmonary fibrosis in mice.

1 reference

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Simvastatin attenuates lipopolysaccharide-induced airway mucus hypersecretion in rats

1 reference

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Pravastatin attenuates allergic airway inflammation by suppressing antigen sensitisation, interleukin 17 production and antigen presentation in the lung

1 reference

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Short term fluvastatin treatment lowers serum asymmetric dimethylarginine levels in patients with metabolic syndrome

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Arginase inhibition protects against allergen-induced airway obstruction, hyperresponsiveness, and inflammation

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Transiently, paralleled upregulation of arginase and nitric oxide synthase and the effect of both enzymes on the pathology of asthma

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19 August 2018

Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

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Reversible and irreversible airway inflammation and fibrosis in mice exposed to inhaled ovalbumin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2990975

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1 reference

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Arginase and autoimmune inflammation in the central nervous system

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Airway fibrosis in a mouse model of airway inflammation.

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Expression and regulation of the gene for arginase I in mouse salivary glands: requirement of CCAAT/enhancer-binding protein alpha for the expression in the parotid gland

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Exhaled Nitric Oxide after β2-agonist Inhalation and Spirometry in Asthma

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2 December 2018

Pathogenesis of asthma

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2010.09.003

7 January 2021

Early thickening of the reticular basement membrane in children with difficult asthma

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7 January 2021

Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin

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7 January 2021

Simvastatin does not exhibit therapeutic anti-inflammatory effects in asthma

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Histological and histochemical uses of periodic acid

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The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

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Influence of cigarette smoke on the arginine pathway in asthmatic airways: increased expression of arginase I

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2010.09.003

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2010.09.003

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https://api.crossref.org/works/10.1016%2FJ.TRSL.2010.09.003

7 January 2021

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7 January 2021

Airway remodeling in asthma

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta stimulates arginase activity in macrophages. Implications for the regulation of macrophage cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21078495

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TRSL.2010.09.003

1 reference

Europe PubMed Central

3 October 2017

1 reference

Europe PubMed Central

3 October 2017

1 reference

Europe PubMed Central

3 October 2017

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