C-X-C motif chemokine receptor 4 (Q415718)

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mammalian protein found in Homo sapiens
  • LAP-3
  • NPYRL
  • SDF-1 receptor
  • LESTR
  • chemokine receptor
  • stromal cell-derived factor 1 receptor
  • leukocyte-derived seven transmembrane domain receptor
  • neuropeptide Y3 receptor
  • chemokine (C-X-C motif) receptor 4
  • C-X-C chemokine receptor type 4
  • lipopolysaccharide-associated protein 3
  • neuropeptide Y receptor Y3
  • seven transmembrane helix receptor
  • HM89
  • fusin
  • seven-transmembrane-segment receptor, spleen
  • LPS-associated protein 3
  • CXCR4
  • CD184 antigen
  • LCR1
  • FB22
  • Receptors, CXCR4
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Language Label Description Also known as
English
C-X-C motif chemokine receptor 4
mammalian protein found in Homo sapiens
  • LAP-3
  • NPYRL
  • SDF-1 receptor
  • LESTR
  • chemokine receptor
  • stromal cell-derived factor 1 receptor
  • leukocyte-derived seven transmembrane domain receptor
  • neuropeptide Y3 receptor
  • chemokine (C-X-C motif) receptor 4
  • C-X-C chemokine receptor type 4
  • lipopolysaccharide-associated protein 3
  • neuropeptide Y receptor Y3
  • seven transmembrane helix receptor
  • HM89
  • fusin
  • seven-transmembrane-segment receptor, spleen
  • LPS-associated protein 3
  • CXCR4
  • CD184 antigen
  • LCR1
  • FB22
  • Receptors, CXCR4

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
RING finger protein 113A regulates C-X-C chemokine receptor type 4 stability and signaling
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Actin-binding protein drebrin regulates HIV-1-triggered actin polymerization and viral infection
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
CXCR4-CCR5: a couple modulating T cell functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Cutting edge: association of the motor protein nonmuscle myosin heavy chain-IIA with the C terminus of the chemokine receptor CXCR4 in T lymphocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
A functional heteromeric MIF receptor formed by CD74 and CXCR4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
Constitutive association of cell surface CCR5 and CXCR4 in the presence of CD4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
F-actin-binding protein drebrin regulates CXCR4 recruitment to the immune synapse
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
retrieved
8 April 2019
stated in
CD164 regulates the tumorigenesis of ovarian surface epithelial cells through the SDF-1α/CXCR4 axis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IPI
cell component
cell surface
determination method
IDA
5 references
retrieved
8 April 2019
stated in
Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IDA
retrieved
8 April 2019
stated in
Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IDA
retrieved
8 April 2019
stated in
beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IDA
retrieved
8 April 2019
stated in
CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow
GOA
curator
UniProt
UniProt protein ID
P61073
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IDA
retrieved
8 April 2019
stated in
CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P61073
determination method
IDA
biological process
Gene Atlas image
PBB GE CXCR4 217028 at fs.png
732 × 530; 11 KB
0 references
Commons category
CXCR4 receptors
0 references

Identifiers

MeSH descriptor ID
D019718
subject named as
Receptors, CXCR4
0 references
 
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