Th1-Th2: reliable paradigm or dangerous dogma? (Q41574419)

4 October 2017

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title

Th1-Th2: reliable paradigm or dangerous dogma? (English)

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4 October 2017

Allen JE

1

1 reference

PubMed ID

9267081

4 October 2017

Maizels RM

series ordinal

2

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4 October 2017

1 August 1997

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4 October 2017

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4 October 2017

18

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4 October 2017

8

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4 October 2017

387-392

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Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

4 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Susceptibility to Leishmania major infection in interleukin-4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

IL-4-deficient Balb/c mice resist infection with Leishmania major

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

The induction of protective immunity to Leishmania major in the BALB/c mouse by interleukin 4 treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Cytokine control of Leishmania infection in the BALB/c mouse: enhancement and inhibition of parasite growth by local administration of IL-2 or IL-4 is species and time dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Cytokine interactions in experimental cutaneous leishmaniasis. Interleukin 4 synergizes with interferon-gamma to activate murine macrophages for killing of Leishmania major amastigotes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Exacerbation of experimental murine cutaneous leishmaniasis with CD4+Leishmania major-specific T cell lines or clones which secrete interferon-γ and mediate parasite-specific delayed-type hypersensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

T cell and non-T cell compartments can independently determine resistance to Leishmania major

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Early IL-4 production does not predict susceptibility to Leishmania major

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

The role of CD4+ T-cells in the immune response to Plasmodium chabaudi

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Immunity to the liver stage of malaria.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

T cells and malaria: is Th1 cell activation a prerequisite for pathology?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Natural Immunity: A T-Cell-Independent Pathway of Macrophage Activation, Defined in the scid Mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Different roles for interleukin-4 during the course of Toxoplasma gondii infection

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Protective effect of low doses of an anti-IL-4 monoclonal antibody in a murine model of acute toxoplasmosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Purified protein derivative of Mycobacterium tuberculosis and excretory-secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Human TH1 and TH2 subsets: doubt no more

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Selection of a human T helper type 1-like T cell subset by mycobacteria

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Defining protective responses to pathogens: cytokine profiles in leprosy lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Roles of alpha beta and gamma delta T cell subsets in viral immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

The Th1-Th2 hypothesis of HIV infection: new insights

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Ability of HIV to promote a TH1 to TH0 shift and to replicate preferentially in TH2 and TH0 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Delayed hypersensitivity, immune deviation, antigen processing and T-cell subset selection in syphilis pathogenesis and vaccine design

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Cytokine-mediated regulation of chronic intestinal helminth infection

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

A critical role for stem cell factor and c-kit in host protective immunity to an intestinal helminth

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Regulation and biological function of helminth-induced cytokine responses

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Nippostrongylus brasiliensis: cytokine responses and nematode expulsion in normal and IL-4-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

The expanding universe of T-cell subsets: Th1, Th2 and more.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Brugia malayi: acquired resistance to microfilariae in BALB/c mice correlates with local Th2 responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Role of nitric oxide in host defense against an extracellular, metazoan parasite, Brugia malayi.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Th1-like antifilarial immune responses predominate in antigen-negative persons

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Immunity to onchocerciasis: putative immune persons produce a Th1-like response to Onchocerca volvulus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

T cell responsiveness correlates differentially with antibody isotype levels in clinical and asymptomatic filariasis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

IgE and protective immunity to helminth infections

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Functional dichotomy in the CD4+T cell response to Schistosoma mansoni

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon gamma knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Accelerated clearance of Onchocerca microfilariae and resistance to reinfection in interleukin-4 gene knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Immunity to helminths: is too much IgE parasite--rather than host-protective?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Elevated proliferation and interleukin-4 release from CD4+ cells after chemotherapy in human Schistosoma haematobium infection

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

T-cell activation and the balance of antibody isotypes in human lymphatic filariasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

An eosinophil-dependent mechanism for the antitumor effect of interleukin-4

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

The Th1/Th2 paradigm and the allograft response

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Cytokines and transplantation: Th1/Th2 regulation of the immune response to solid organ transplants in the adult.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Th1 and Th2 subsets: paradigms lost?

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

The instructive role of innate immunity in the acquired immune response

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

Immunological modulation and evasion by helminth parasites in human populations

1 reference

https://api.crossref.org/works/10.1016%2FS0167-5699%2897%2901102-X

7 January 2021

10.1016/S0167-5699(97)01102-X

Identifiers

DOI

1 reference

4 October 2017

1 reference

PubMed ID

9267081