Endogenous protective mechanisms in myocardial ischemia: hibernation and ischemic preconditioning (Q41592327)

4 October 2017

1 reference

title

Endogenous protective mechanisms in myocardial ischemia: hibernation and ischemic preconditioning (English)

1 reference

4 October 2017

0 references

1 reference

G Heusch

1

1 reference

PubMed ID

9293953

4 October 2017

R Schulz

series ordinal

2

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PubMed ID

9293953

4 October 2017

language of work or name

English

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publication date

1 August 1997

1 reference

American Journal of Cardiology

4 October 2017

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4 October 2017

80

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4 October 2017

3A

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4 October 2017

26A-33A

1 reference

The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogs

4 October 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocardial 'stunning' in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocardial perfusion-contraction matching. Implications for coronary heart disease and hibernation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Sustained regional dysfunction produced by prolonged coronary stenosis: gradual recovery after reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Acute hibernation and reperfusion of the ischemic heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Metabolic response to prolonged reduction of myocardial blood flow distal to a severe coronary artery stenosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocardial hibernation in the ischemic neonatal heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Active downregulation of myocardial energy requirements during prolonged moderate ischemia in swine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Recruitment of an inotropic reserve in moderately ischemic myocardium at the expense of metabolic recovery. A model of short-term hibernation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ultrastructural correlates of left ventricular contraction abnormalities in patients with chronic ischemic heart disease: determinants of reversible segmental asynergy postrevascularization surgery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocyte degeneration and cell death in hibernating human myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Functional and structural alterations with 24-hour myocardial hibernation and recovery after reperfusion. A pig model of myocardial hibernation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Development of short-term myocardial hibernation. Its limitation by the severity of ischemia and inotropic stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Dobutamine stress echocardiography identifies hibernating myocardium and predicts recovery of left ventricular function after coronary revascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Recruitment of a time-dependent inotropic reserve by postextrasystolic potentiation in normal and reperfused myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Calcium responsiveness in regional myocardial short-term hibernation and stunning in the in situ porcine heart. Inotropic responses to postextrasystolic potentiation and intracoronary calcium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Epinephrine-stimulated contractile and metabolic reserve in postischemic rat myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Post-ejection wall thickening as a marker of successful short term hibernation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Hibernating myocardium: a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Incremental doses of dobutamine induce a biphasic response in dysfunctional left ventricular regions subtending coronary stenoses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Mechanical and metabolic functions in pig hearts after 4 days of chronic coronary stenosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Mechanism of impaired myocardial function during progressive coronary stenosis in conscious pigs. Hibernation versus stunning?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

18F-2-deoxyglucose deposition and regional flow in pigs with chronically dysfunctional myocardium. Evidence for transmural variations in chronic hibernating myocardium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

The hibernating myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Acute changes in global and regional rest left ventricular function after successful coronary angioplasty: comparative results in stable and unstable angina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Regional myocardial blood flow in stable angina pectoris associated with isolated significant narrowing of either the left anterior descending or left circumflex coronary artery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Influence of direct myocardial revascularization on left ventricular asynergy and function in patients with coronary heart disease. With and without previous myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocardial viability in patients with Q wave myocardial infarction and no residual ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Selection of angina-free patients with severe left ventricular dysfunction for myocardial revascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Mechanisms of chronic regional postischemic dysfunction in humans. New insights from the study of noninfarcted collateral-dependent myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Echocardiography during infusion of dobutamine for identification of reversibly dysfunction in patients with chronic coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Only hibernating myocardium invariably shows early recovery after coronary revascularization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocardial protection with preconditioning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

The transient nature of the effect of ischemic preconditioning on myocardial infarct size and ventricular arrhythmia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ischemic preconditioning reduces infarct size in swine myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ischaemic preconditioning limits infarct size in the rat heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning of the heart by repeated stunning: attenuation of post-ischemic dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning does not attenuate myocardial stunning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning improves energy metabolism during reperfusion but does not attenuate myocardial stunning in porcine hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ischemic preconditioning preserves creatine phosphate and intracellular pH

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Energy metabolism in preconditioned and control myocardium: Effect of total ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Loss of myocardial protection after preconditioning correlates with the time course of glycogen recovery within the preconditioned segment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Mechanism of preconditioning. Ionic alterations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Protective effects of preconditioning of the ischaemic myocardium involve cyclo-oxygenase products

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Effect of preconditioning ischemia on reperfusion arrhythmias after coronary artery occlusion and reperfusion in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Antiarrhythmic effects of preconditioning in anaesthetised dogs and rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Protection against autonomic denervation following acute myocardial infarction by preconditioning ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Involvement of endogenous adenosine in ischaemic preconditioning in swine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Effect of coronary hyperperfusion on regional myocardial function and oxygen consumption of stunned myocardium in pigs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Cardiac protection by ischaemic preconditioning is not mediated by myocardial stunning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

The protection of ischaemic preconditioning can be reinstated in the rabbit heart after the initial protection has waned.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ischaemic preconditioning--time course of renewal in the pig.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Ischaemic preconditioning is not dependent on neutrophils or glycolytic substrate at reperfusion in rabbit heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Myocardial infarct size-limiting effect of ischemic preconditioning was not attenuated by oxygen free-radical scavengers in the rabbit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Cardioprotective effects of ischaemic preconditioning are not mediated by prostanoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Alpha 1-adrenoceptor activation mediates the infarct size-limiting effect of ischemic preconditioning through augmentation of 5'-nucleotidase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Role of bradykinin in protection of ischemic preconditioning in rabbit hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Limitation of myocardial infarct size by adenosine A1 receptor activation is abolished by protein kinase C inhibitors in the rabbit.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

alpha 1-adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Pretreatment with pertussis toxin blocks the protective effects of preconditioning: evidence for a G-protein mechanism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Role of nitric oxide, muscarinic receptors, and the ATP-sensitive K+ channel in mediating the effects of acetylcholine to mimic preconditioning in dogs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Role of myocardial ATP-sensitive potassium channels in mediating preconditioning in the dog heart and their possible interaction with adenosine A1-receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Synergistic modulation of ATP-sensitive K+ currents by protein kinase C and adenosine. Implications for ischemic preconditioning.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Protein kinase C activates ATP-sensitive K+ current in human and rabbit ventricular myocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Does ischemic preconditioning in the human involve protein kinase C and the ATP-dependent K+ channel? Studies of contractile function after simulated ischemia in an atrial in vitro model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Does ischemic preconditioning trigger translocation of protein kinase C in the canine model?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Role of activation of protein kinase C in the infarct size-limiting effect of ischemic preconditioning through activation of ecto-5'-nucleotidase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

No prevention of ischemic preconditioning by the protein kinase C inhibitor staurosporine in swine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Preconditioning the human myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Rapid expression of heat shock protein in the rabbit after brief cardiac ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Stress proteins and myocardial protection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Does preconditioning protect the coronary vasculature from subsequent ischemia/reperfusion injury?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Metabolic Adaptation During a Sequence of No-Flow and Low-Flow Ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Metabolic and functional consequences of successive no-flow and sustained low-flow ischaemia; a 31P MRS study in rat hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

Intraischemic preconditioning. Increased tolerance to sustained low-flow ischemia by a brief episode of no-flow ischemia without intermittent reperfusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2897%2900455-4

10.1016/S0002-9149(97)00455-4

7 January 2021

Identifiers

DOI

1 reference

4 October 2017

1 reference

PubMed ID

9293953