HSP70 mediates degradation of the p65 subunit of nuclear factor κB to inhibit inflammatory signaling (Q41595626)

4 October 2017

HSP70 mediates degradation of the p65 subunit of nuclear factor κB to inhibit inflammatory signaling (English)

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4 October 2017

Takashi Tanaka

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4 October 2017

Azusa Shibazaki

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2

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4 October 2017

Rumiko Ono

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3

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4 October 2017

Tsuneyasu Kaisho

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4

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4 October 2017

language of work or name

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16 December 2014

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4 October 2017

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4 October 2017

7

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4 October 2017

356

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4 October 2017

ra119

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New regulators of NF-kappaB in inflammation

4 October 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Pattern recognition receptors and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Role of the NF-kappaB pathway in the pathogenesis of human disease states

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Recent advances in the genetics of autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Hsp70 chaperones: cellular functions and molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Protein degradation and protection against misfolded or damaged proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Protein quality control: chaperones culling corrupt conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

The inhibition of LPS-induced production of inflammatory cytokines by HSP70 involves inactivation of the NF-kappaB pathway but not the MAPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Enhanced heat shock protein 70 expression alters proteasomal degradation of IkappaB kinase in experimental acute respiratory distress syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

PDLIM2 inhibits T helper 17 cell development and granulomatous inflammation through degradation of STAT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Oral administration of geranylgeranylacetone improves survival rate in a rat endotoxin shock model: administration timing and heat shock protein 70 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

An anti-ulcer drug, geranylgeranylacetone, suppresses inducible nitric oxide synthase in cultured vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

A role for HSP70 in protecting against indomethacin-induced gastric lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Molecular chaperone targeting and regulation by BAG family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

BAG-6 is essential for selective elimination of defective proteasomal substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Negative regulation of NF-kappaB signaling by PIAS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

IkappaBNS inhibits induction of a subset of Toll-like receptor-dependent genes and limits inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Aryl hydrocarbon receptor in combination with Stat1 regulates LPS-induced inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

HSP70 protects against TNF-induced lethal inflammatory shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Degradation-mediated protein quality control in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Rad23 promotes the targeting of proteolytic substrates to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

UBA domains of DNA damage-inducible proteins interact with ubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005533

10.1126/SCISIGNAL.2005533

21 January 2018

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DOI

1 reference

4 October 2017

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