Functional expression of human 5-HT1A receptors and differential coupling to second messengers in CHO cells (Q41610555)

5 October 2017

Functional expression of human 5-HT1A receptors and differential coupling to second messengers in CHO cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1448178

27 September 2022

author name string

J. R. Raymond

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1448178

27 September 2022

F. J. Albers

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1448178

27 September 2022

J. P. Middleton

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1448178

27 September 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1448178

27 September 2022

publication date

1 August 1992

1 reference

Naunyn-Schmiedeberg's Archives of Pharmacology

5 October 2017

1 reference

5 October 2017

346

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5 October 2017

127-137

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5 October 2017

2

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https://scigraph.springernature.com/pub.10.1007/bf00165293

5 October 2017

0 references

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Receptor-mediated activation of phospholipase A2 and arachidonic acid release in signal transduction

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Receptors linked to inhibition of adenylate cyclase: additional signaling mechanisms

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Short-term regulation of Na+/K+ adenosine triphosphatase by recombinant human serotonin 5-HT1A receptor expressed in HeLa cells

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Cell-specific signaling of the 5-HT1A receptor. Modulation by protein kinases C and A.

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The human 5-HT1A receptor expressed in HeLa cells stimulates sodium-dependent phosphate uptake via protein kinase C

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Two 5-HT receptors linked to adenylate cyclase in guinea pig hippocampus are discriminated by 5-carboxamidotryptamine and spiperone.

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Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell

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Transfected D2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells

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Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons

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5-HT1A-receptors mediate stimulation of adenylate cyclase in rat hippocampus.

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Piperazine derivatives including the putative anxiolytic drugs, buspirone and ipsapirone, are agonists at 5-HT1A receptors negatively coupled with adenylate cyclase in hippocampal neurons

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5-HT1A receptor agonists inhibit carbachol-induced stimulation of phosphoinositide turnover in the rat hippocampus.

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Multiple Gi protein subtypes regulate a single effector mechanism

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Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

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Alpha 2-adrenergic receptor stimulation of phospholipase A2 and of adenylate cyclase in transfected Chinese hamster ovary cells is mediated by different mechanisms

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Intracellular Ca2+ and protein kinase C interact to regulate alpha 1-adrenergic- and bradykinin receptor-stimulated phospholipase A2 activation in Madin-Darby canine kidney cells

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5-HT1A and histamine H1 receptors in HeLa cells stimulate phosphoinositide hydrolysis and phosphate uptake via distinct G protein pools.

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Electrophysiological investigation of the adaptive response of the 5-HT system to the administration of 5-HT1A receptor agonists

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Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G-proteins following transfection of the human alpha 2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor w

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Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation

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A highly sensitive adenylate cyclase assay

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Dual couplings of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein

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Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes

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Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes

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Effector coupling mechanisms of the cloned 5-HT1A receptor

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Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture.

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A transfected m5 muscarinic acetylcholine receptor stimulates phospholipase A2 by inducing both calcium influx and activation of protein kinase C

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The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor

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Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserin

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Agonist/antagonist interactions with cloned human 5-HT1A receptors: variations in intrinsic activity studied in transfected HeLa cells

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An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

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12 December 2020

A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein Gi that amplifies ATP-mediated arachidonic acid release

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12 December 2020

Identifiers

DOI

10.1007/BF00165293

1 reference

5 October 2017

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