Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes (Q41610819)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10759686%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes (English)

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5 November 2019

3

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5 November 2019

author name string

H C Rawden

series ordinal

1

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5 November 2019

G O Kokwaro

series ordinal

2

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5 November 2019

G Edwards

series ordinal

4

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5 November 2019

language of work or name

English

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publication date

1 April 2000

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British Journal of Clinical Pharmacology

5 November 2019

published in

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5 November 2019

volume

49

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5 November 2019

issue

4

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5 November 2019

page(s)

313-322

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Protein measurement with the Folin phenol reagent

5 November 2019

cites work

1 reference

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

6 June 2018

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Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

6 June 2018

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Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014938

Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014938

Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

6 June 2018

1 reference

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Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014938

Selective inhibitors of cytochromes P450.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014938

Flavin-containing monooxygenases: enzymes adapted for multisubstrate specificity

6 June 2018

1 reference

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Predictability of the in vivo metabolism of verapamil from in vitro data: contribution of individual metabolic pathways and stereoselective aspects

6 June 2018

1 reference

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Activation of CYP3A4: evidence for the simultaneous binding of two substrates in a cytochrome P450 active site.

6 June 2018

1 reference

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Study of the in vitro bioactivation of albendazole in human liver microsomes and hepatoma cell lines

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1046%2FJ.1365-2125.2000.00170.X

Flavin-containing monooxygenase activity in human liver microsomes

21 January 2018

1 reference

12 December 2020

Benzimidazoles in a wormy world

1 reference

12 December 2020

Inducing effect of albendazole on rat liver drug-metabolizing enzymes and metabolite pharmacokinetics

1 reference

12 December 2020

Sulphoxidation of albendazole by the FAD-containing and cytochrome P-450 dependent mono-oxygenases from pig liver microsomes

1 reference

12 December 2020

The metabolism of benzimidazole anthelmintics

1 reference

12 December 2020

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes

1 reference

12 December 2020

Albendazole sulfonation by rat liver cytochrome P-450c

1 reference

12 December 2020

Involvement of P4503A in the metabolism of 7,8-benzoflavone by human liver microsomes

1 reference

12 December 2020

Modulation of cytochrome P450 activities by 7,8-benzoflavone and its metabolites

1 reference

12 December 2020

Use of in vitro human metabolism studies in drug development. An industrial perspective

1 reference

12 December 2020

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

1 reference

12 December 2020

Rapid and sensitive method for the determination of albendazole and albendazole sulphoxide in biological fluids

1 reference

12 December 2020

Inhibition of the microsomal N-hydroxylation of 2-amino-6-nitrotoluene by a metabolite of methimazole

1 reference

12 December 2020

A convenient method to discriminate between cytochrome P450 enzymes and flavin-containing monooxygenases in human liver microsomes

1 reference

12 December 2020

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

1 reference

12 December 2020

10.1046/J.1365-2125.2000.00170.X

Identifiers

DOI

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5 November 2019

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5 November 2019

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