Dramatic inhibition of amiodarone metabolism induced by grapefruit juice (Q41610920)

5 October 2017

Dramatic inhibition of amiodarone metabolism induced by grapefruit juice (English)

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5 October 2017

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C C Libersa

1

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5 October 2017

S A Brique

2

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5 October 2017

K B Motte

3

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5 October 2017

J F Caron

4

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5 October 2017

L M Guédon-Moreau

5

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5 October 2017

L Humbert

6

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5 October 2017

A Vincent

7

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5 October 2017

P Devos

8

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5 October 2017

M A Lhermitte

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5 October 2017

language of work or name

English

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publication date

1 April 2000

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British Journal of Clinical Pharmacology

5 October 2017

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5 October 2017

49

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5 October 2017

4

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5 October 2017

373-378

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Trough concentrations of cyclosporine in blood following administration with grapefruit juice

5 October 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Drug interactions with grapefruit juice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Antiarrhythmic actions of amiodarone: a profile of a paradoxical agent

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Amiodarone N-deethylation in human liver microsomes: involvement of cytochrome P450 3A enzymes (first report).

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

The fate of naringin in humans: A key to grapefruit juice-drug interactions?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Analysis of covariance using the rank transformation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

The effect of amiodarone, a new anti-anginal drug, on cardiac muscle

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Amiodarone and desethylamiodarone elimination kinetics following withdrawal of long-term amiodarone maintenance therapy.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Recent advances in understanding the pharmacology of amiodarone.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Interaction of citrus juices with felodipine and nifedipine

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Effects of amiodarone and its active metabolite desethylamiodarone on the ventricular defibrillation threshold.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

In vitro inhibition of midazolam and quinidine metabolism by flavonoids.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Steady-state serum amiodarone concentrations: relationships with antiarrhythmic efficacy and toxicity.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014943

Identification and measurement of desethylamiodarone in blood plasma specimens from amiodarone-treated patients

19 August 2018

1 reference

12 December 2020

Serum concentrations of amiodarone during long term therapy. Relation to dose, efficacy and toxicity

1 reference

12 December 2020

Amiodarone pharmacokinetics

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12 December 2020

A comparison of the electrophysiologic effects of intravenous and oral amiodarone in the same patient

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12 December 2020

Pharmacodynamics of Intravenous Amiodarone in the Dog

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12 December 2020

Effect of amiodarone on conduction and refractoriness of the His-Purkinje system in the human heart

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12 December 2020

Electrophysiologic effects of amiodarone: experimental and clinical observation relative to serum and tissue drug concentrations

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12 December 2020

QT prolongation and the antiarrhythmic efficacy of amiodarone

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12 December 2020

Acute and chronic effects of amiodarone on ventricular refractoriness, intraventricular conduction and ventricular tachycardia induction

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12 December 2020

Effect of phenobarbitone on the pharmacokinetics and tissue levels of amiodarone in the rat

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12 December 2020

In vitro metabolism of amiodarone by rabbit and rat liver and small intestine

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12 December 2020

Comparative electrophysiologic effects of intravenous amiodarone and desethylamiodarone in dogs: evidence for clinically relevant activity of the metabolite

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12 December 2020

Spectral perturbation of human microsomal cytochrome P-450 by flavonoid binding

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12 December 2020

Amiodarone and desethylamiodarone concentrations in plasma and tissues of surgically treated patients on long-term oral amiodarone treatment

1 reference

12 December 2020

High-performance liquid chromatographic assay for amiodarone N-deethylation in microsomes of rat liver

1 reference

12 December 2020

Effect of grapefruit juice on blood cyclosporin concentration

1 reference

12 December 2020

Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine

1 reference

12 December 2020

Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice

1 reference

12 December 2020

Efficacy, safety, and determinants of conversion of atrial fibrillation and flutter with oral amiodarone

1 reference

12 December 2020

Grapefruit component interacting with rat and human P450 CYP3A: possible involvement of non-flavonoid components in drug interaction

1 reference

12 December 2020

Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine

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12 December 2020

10.1046/J.1365-2125.2000.00163.X

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DOI

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5 October 2017

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5 October 2017

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