Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology (Q41629826)

5 October 2017

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title

Neuropharmacological mechanisms of nerve agent-induced seizure and neuropathology (English)

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5 October 2017

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McDonough JH Jr

1

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5 October 2017

Shih TM

series ordinal

2

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5 October 2017

publication date

1 September 1997

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Neuroscience & Biobehavioral Reviews

5 October 2017

published in

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5 October 2017

volume

21

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5 October 2017

issue

5

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5 October 2017

page(s)

559-579

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Efficacy comparison of scopolamine and diazepam against soman-induced debilitation in guinea pigs

5 October 2017

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Persistent effects of sarin and dieldrin upon the primate electroencephalogram

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Early dendritic changes in hippocampal pyramidal neurones (field CA1) of rats subjected to acute soman intoxication: a light microscopic study

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Behavioral decrements persist in rhesus monkeys trained on a serial probe recognition task despite protection against soman lethality by butyrylcholinesterase.

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Behavioral efficacy of diazepam against nerve agent exposure in rhesus monkeys

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7 January 2021

Brain and Serum Concentrations of Diazepam in Experimental Epilepsy

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Variation in the expression of c-fos after intoxication by soman. Comparative study using in situ hybridization and immunohistochemistry

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7 January 2021

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

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7 January 2021

Cholinergic systems influence local cerebral glucose use in specific anatomical areas: diisopropyl phosphorofluoridate versus soman

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7 January 2021

Soman-induced convulsions: significance of changes in levels of blood electrolytes, gases, glucose, and insulin

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7 January 2021

Cholinolytics in the treatment of anticholinesterase poisoning. V. The effectiveness of Parpanit with oximes in the treatment of organophosphorus poisoning

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7 January 2021

Brain catecholamine metabolism changes and hypothermia in intoxication by anticholinesterase agents

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7 January 2021

Effects of physostigmine, paraoxon and soman on brain GABA level and metabolism

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7 January 2021

Assessment of primary neuronal culture as a model for soman-induced neurotoxicity and effectiveness of memantine as a neuroprotective drug

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7 January 2021

The protection of primates against soman poisoning by pretreatment with pyridostigmine

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7 January 2021

Long-term effects of an organophosphate upon the human electroencephalogram

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7 January 2021

Progress in medical defense against nerve agents

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7 January 2021

Brain norepinephrine reductions in soman-intoxicated rats: association with convulsions and AChE inhibition, time course, and relation to other monoamines

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7 January 2021

Tonic activation of locus coeruleus neurons by systemic or intracoerulear microinjection of an irreversible acetylcholinesterase inhibitor: increased discharge rate and induction of C-fos

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7 January 2021

Early changes in the rat hippocampus following seizures induced by bicuculline or L-allylglycine: a light and electron microscope study

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7 January 2021

Elevated choline levels in brain. A non-cholinergic component of organophosphate toxicity

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7 January 2021

Concomitant increases in the levels of choline and free fatty acids in rat brain: evidence supporting the seizure-induced hydrolysis of phosphatidylcholine.

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7 January 2021

Neurotransmitter changes in guinea-pig brain regions following soman intoxication

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7 January 2021

Effect of acute physostigmine-hyoscine pretreatment on the neurochemical changes produced by soman in the guinea-pig.

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7 January 2021

The use of therapeutic mixtures in the treatment of cholinesterase inhibition.

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7 January 2021

The protection of animals against organophosphate poisoning by pretreatment with a carbamate

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7 January 2021

Effects of soman on cerebral astrocyte plasma membranes: a freeze-fracture study

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7 January 2021

Dual mechanism of the antidotal action of atropine-like drugs in poisoning by organophosphorus anticholinesterases

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7 January 2021

A brief history of epilepsy and its therapy in the Western Hemisphere

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7 January 2021

Hierarchy of seizure states in the electrogenic limbic status epilepticus model: behavioral and electrographic observations of initial states and temporal progression

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7 January 2021

Electrogenic status epilepticus induced from numerous limbic sites

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7 January 2021

Mapping of limbic seizure progressions utilizing the electrogenic status epilepticus model and the 14C-2-deoxyglucose method

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7 January 2021

Efficacy comparison of scopolamine (SCP) and diazepam (DZ) against soman-induced lethality in guinea pigs

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7 January 2021

Decreased brain pathology in organophosphate-exposed rhesus monkeys following benzodiazepine therapy

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7 January 2021

Potentiation of malaoxon-induced convulsions by lithium: early neuronal injury, phosphoinositide signaling, and calcium

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7 January 2021

Effects of repeated administration of soman on schedule-controlled behavior and brain in the rat.

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7 January 2021

Reduction by diazepam of repetitive electrical activity and toxicity resulting from soman.

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7 January 2021

Studies on the mechanism of the protective and antidotal actions of diazepam in organophosphate poisining

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7 January 2021

Acetylcholine content in rat brain is elevated by status epilepticus induced by lithium and pilocarpine

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7 January 2021

Effective doses of some cholinolytics in the treatment of anticholinesterase poisoning

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7 January 2021

Long-term study of brain lesions following soman, in comparison to DFP and metrazol poisoning

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7 January 2021

Sarin-induced neuropathology in rats

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7 January 2021

Long-term sequelae of soman exposure: hormonal rhythms two weeks postexposure to a single dose

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7 January 2021

Possible role of gamma-aminobutyric acid in paraoxon-induced convulsions.

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7 January 2021

Pyridostigmine used as a nerve agent pretreatment under wartime conditions

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7 January 2021

Assessment of motor performance decrement following soman poisoning in mice

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7 January 2021

Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus

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7 January 2021

Transient impairment of the gabaergic function during initiation of soman-induced seizures

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7 January 2021

Neuroprotective activity of glutamate receptor antagonists against soman-induced hippocampal damage: quantification with an omega 3 site ligand

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7 January 2021

Changes in hippocampal acetylcholine and glutamate extracellular levels during soman-induced seizures: influence of septal cholinoceptive cells

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7 January 2021

Modulation of soman-induced neuropathology with an anticonvulsant regimen

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7 January 2021

Antiepileptic effects of NBQX against soman-induced seizures

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7 January 2021

Coadministration of atropine, NBQX and TCP against soman-induced seizures

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7 January 2021

The role of brain edema in epileptic brain damage induced by systemic kainic acid injection

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7 January 2021

Treatment of poisoning by soman.

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7 January 2021

Histological and histochemical changes in the central nervous system of the rat poisoned by an irreversible anticholinesterase organophosphorus compound

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7 January 2021

Effect of diazepam upon soman-induced seizure activity and convulsions

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7 January 2021

Evidence that alterations in gamma-aminobutyric acid and acetylcholine in rat striata and cerebella are not related to soman-induced convulsions

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7 January 2021

Acute effects of Soman, Sarin, and Tabun on cyclic nucleotide metabolism in rat striatum

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7 January 2021

Modification of cholinergically induced convulsive activity and cyclic GMP levels in the CNS

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7 January 2021

Examination of the role of central cholinergic mechanisms in the therapeutic effects of HI-6 in organophosphate poisoning

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7 January 2021

Dissociation of locomotor depression and ChE activity after DFP, soman and sarin

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7 January 2021

Protective effect of diazepam pretreatment on soman-induced brain lesion formation

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7 January 2021

The effects of blood flow and detoxification on in vivo cholinesterase inhibition by soman in rats

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7 January 2021

Atropine and/or diazepam therapy protects against soman-induced neural and cardiac pathology.

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7 January 2021

Direct microinjection of soman or VX into the amygdala produces repetitive limbic convulsions and neuropathology

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7 January 2021

Pharmacological modulation of soman-induced seizures.

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7 January 2021

A study of the N-methyl-D-aspartate antagonistic properties of anticholinergic drugs

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7 January 2021

A new model of partial status epilepticus based on kindling

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7 January 2021

Pathology of nerve agents: perspectives on medical management

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7 January 2021

Cerebral metabolic effects of organophosphorus anticholinesterase compounds

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7 January 2021

Differences in central and peripheral neural actions between soman and diisopropyl fluorophosphate, organophosphorus inhibitors of acetylcholinesterase

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7 January 2021

The cholinesterase inhibitor soman increases inositol trisphosphate in rat brain

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7 January 2021

Effect of soman exposure on the acquisition of an operant alternation task

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7 January 2021

The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system

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7 January 2021

Role of early edema in the development of regional seizure-related brain damage

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7 January 2021

Anti-parkinsonian agents are phencyclidine agonists and N-methyl-aspartate antagonists

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7 January 2021

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7 January 2021

Changes in local cerebral glucose utilization induced by convulsants

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

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7 January 2021

Neurology and neuropathology of Soman-induced brain injury: an overview

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7 January 2021

Autoradiographic analysis of [35S]TBPS binding in entorhinal cortex-kindled rat brains

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7 January 2021

Behavioral performance, brain histology, and EEG sequela after immediate combined atropine/diazepam treatment of soman-intoxicated rats

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7 January 2021

Modification of Rat Brain 5-Hydroxytryptamine Metabolism by Sublethal Doses of Organophosphate Agents

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7 January 2021

Long-term behavioral changes in rats following organophosphonate exposure

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7 January 2021

Effects of the organophosphorus compound, O-ethyl-N-dimethyl-phosphoramidocyanidate (tabun), on flavor aversions, locomotor activity, and rotarod performance in rats.

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7 January 2021

Effects of diazepam on epileptiform patterns of bioelectrical activity of the rabbit's brain induced by fluostigmine

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7 January 2021

Soman induced changes in brain regional glucose use.

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7 January 2021

Soman-induced convulsions affect the inositol lipid signaling system: potentiation by lithium; attenuation by atropine and diazepam.

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7 January 2021

Convulsions and cerebral inositol-1-phosphate levels in rats treated with diisopropyl fluorophosphate

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7 January 2021

Cerebral blood flow-metabolism coupling after administration of soman at nontoxic levels

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7 January 2021

Time course effects of soman on acetylcholine and choline levels in six discrete areas of the rat brain

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7 January 2021

Anticonvulsant effects of diazepam and MK-801 in soman poisoning.

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7 January 2021

Cholinergic actions of diazepam and atropine sulfate in soman poisoning

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7 January 2021

Effects of anticholinergic-antiparkinsonian drugs on striatal neurotransmitter levels of rats intoxicated with soman

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7 January 2021

Anticonvulsants for poisoning by the organophosphorus compound soman: Pharmacological mechanisms

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7 January 2021

Effects of repeated injection of sublethal doses of soman on behavior and on brain acetylcholine and choline concentrations in the rat.

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7 January 2021

Cerebral blood flow and metabolism in soman-induced convulsions

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7 January 2021

Soman and Sarin: Clinical Manifestations and Treatment of Accident of Accidental Poisoning by Organophosphates

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7 January 2021

Clinical effects of organophosphorus cholinesterase inhibitors

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7 January 2021

Morphological evidence for increased protein synthesis in CNS neurons after soman exposure

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7 January 2021

Cardiomyopathy in Soman and Sarin intoxicated rats

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7 January 2021

"Epileptic" brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine

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7 January 2021

The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy

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7 January 2021

Reduced GABA-mediated chloride flux in entorhinal cortex-kindled rat brains

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7 January 2021

Pathogenesis of brain lesions caused by experimental epilepsy. Light- and electron-microscopic changes in the rat cerebral cortex following bicuculline-induced status epilepticus

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7 January 2021

Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman

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7 January 2021

Dizocilpine (MK-801) arrests status epilepticus and prevents brain damage induced by soman

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7 January 2021

Synthesis of cholinesterase following poisoning with irreversible anticholinesterases: Effects of theophylline and N6,O2-dibutyryl adenosine 3′,5′-monophosphate on synthesis and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Effects of the nerve agents soman and tabun on the uptake and release of GABA and glutamate in synaptosomes of guinea pig cerebral cortex

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Regional GABA-stimulated chloride uptake in amygdala kindled rats

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Histomorphogenesis of Soman-Induced Encephalocardiomyopathy in Sprague-Dawley Rats

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Early histopathologic and ultrastructural changes in the heart of Sprague-Dawley rats following administration of soman

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Review: cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

The neurotoxicity of subchronic acetylcholinesterase (AChE) inhibition in rat hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Efficacy evaluation of physostigmine and anticholinergic adjuncts as a pretreatment for nerve agent intoxication

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Effectiveness of oral pyridostigmine pretreatment and cholinolytic-oxime therapy against soman intoxication in nonhuman primates

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

Changes in extracellular amino acids during soman- and kainic acid-induced seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2896%2900050-4

7 January 2021

10.1016/S0149-7634(96)00050-4

Identifiers

DOI

1 reference

5 October 2017

1 reference