Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer (Q41630334)

5 October 2017

Cryo-EM Studies of Drp1 Reveal Cardiolipin Interactions that Activate the Helical Oligomer (English)

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cryogenic electron microscopy

5 October 2017

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author

Ryan W Clinton

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878368%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Chris Fröhlich

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878368%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jason A Mears

5

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12 June 2020

author name string

Christopher A Francy

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878368%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Colleen Murphy

4

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12 June 2020

language of work or name

English

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publication date

6 September 2017

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5 October 2017

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12 June 2020

volume

7

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12 June 2020

issue

1

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12 June 2020

page(s)

10744

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Creative Commons Attribution 4.0 International

12 June 2020

copyright license

start time

6 September 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5587723/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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1 reference

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6 October 2017

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Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

6 October 2017

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Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity.

6 October 2017

1 reference

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Cardiolipin Interactions with Proteins

6 October 2017

1 reference

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Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission

6 October 2017

1 reference

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The mechanoenzymatic core of dynamin-related protein 1 comprises the minimal machinery required for membrane constriction.

6 October 2017

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A Dynamin Mutant Defines a Superconstricted Prefission State

6 October 2017

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Specific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1

6 October 2017

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A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission.

6 October 2017

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6 October 2017

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Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

6 October 2017

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Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses

6 October 2017

1 reference

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Cyclin-dependent kinases regulate splice-specific targeting of dynamin-related protein 1 to microtubules.

6 October 2017

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Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein

6 October 2017

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Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

6 October 2017

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An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2

6 October 2017

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6 October 2017

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6 October 2017

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A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke

6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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6 October 2017

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Dnm1 forms spirals that are structurally tailored to fit mitochondria

6 October 2017

1 reference

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6 October 2017

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The stalk region of dynamin drives the constriction of dynamin tubes

6 October 2017

1 reference

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6 October 2017

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6 October 2017

1 reference

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Three-dimensional reconstruction of dynamin in the constricted state

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5587723

Mammalian dynamin-like protein DLP1 tubulates membranes

6 October 2017

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A lethal defect of mitochondrial and peroxisomal fission

6 October 2017

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The dynamin middle domain is critical for tetramerization and higher-order self-assembly

6 June 2018

1 reference

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Robust colorimetric assays for dynamin's basal and stimulated GTPase activities.

6 June 2018

1 reference

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A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy.

6 June 2018

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Early changes in intramitochondrial cardiolipin distribution during apoptosis.

19 August 2018

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Dynamin undergoes a GTP-dependent conformational change causing vesiculation

19 August 2018

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Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

19 August 2018

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Mitochondrial contact sites. Lipid composition and dynamics

30 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28878368

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1038/S41598-017-11008-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878368%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

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12 June 2020

PubMed publication ID

28878368

1 reference