Nicotinic acetylcholine receptors in health and disease (Q41659796)

6 October 2017

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title

Nicotinic acetylcholine receptors in health and disease (English)

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6 October 2017

Lindstrom J

1

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PubMed ID

9396010

6 October 2017

language of work or name

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1 October 1997

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6 October 2017

Molecular Neurobiology

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6 October 2017

15

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6 October 2017

2

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6 October 2017

193-222

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https://scigraph.springernature.com/pub.10.1007/bf02740634

6 October 2017

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cites work

Oral tolerance for the treatment of autoimmune diseases

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12 December 2020

The Alzheimer family of diseases: many etiologies, one pathogenesis?

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12 December 2020

Pharmacological characterization of alpha-bungarotoxin-sensitive acetylcholine receptors immunoisolated from chick retina: contrasting properties of alpha 7 and alpha 8 subunit-containing subtypes

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12 December 2020

Biochemical properties of acetylcholine receptor subunits from Torpedo californica

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12 December 2020

Induction of Interferon-γ, Interleukin-4, and Transforming Growth Factor-β in Rats Orally Tolerized against Experimental Autoimmune Myasthenia Gravis

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12 December 2020

Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner

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12 December 2020

A role for the nicotinic alpha-bungarotoxin receptor in neurite outgrowth in PC12 cells

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12 December 2020

Evidence that tobacco smoking increases the density of (-)-[3H]nicotine binding sites in human brain.

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12 December 2020

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes.

1 reference

12 December 2020

Mutations in different functional domains of the human muscle acetylcholine receptor alpha subunit in patients with the slow-channel congenital myasthenic syndrome

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12 December 2020

Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system

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12 December 2020

A transgenic mouse model of the slow-channel syndrome

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12 December 2020

Acetylcholine differentially affects intracellular calcium via nicotinic and muscarinic receptors on the same population of neurons

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12 December 2020

Molecular and cellular aspects of nicotine abuse

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12 December 2020

Competitive antagonists bridge the alpha-gamma subunit interface of the acetylcholine receptor through quaternary ammonium-aromatic interactions

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12 December 2020

Nicotinic receptors in the development and modulation of CNS synapses.

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12 December 2020

The alpha 5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

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12 December 2020

Cloning of a cDNA coding for the acetylcholine receptor alpha-subunit from a thymoma associated with myasthenia [correction of myastenia] gravis

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12 December 2020

Monoclonal antibodies as probes of acetylcholine receptor structure. 2. Binding to native receptor

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12 December 2020

Volatile general anaesthetic actions on recombinant nACh alpha 7, 5-HT3 and chimeric nACh alpha 7-5-HT3 receptors expressed in Xenopus oocytes

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12 December 2020

Restoration of sensory gating of auditory evoked response by nicotine in fimbria-fornix lesioned rats

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12 December 2020

Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies

1 reference

12 December 2020

T cell reactivity to acetylcholine receptor in rats orally tolerized against experimental autoimmune myasthenia gravis

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12 December 2020

Congenital myasthenic syndrome caused by decreased agonist binding affinity due to a mutation in the acetylcholine receptor epsilon subunit

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12 December 2020

Antibody-mediated neurological disease

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12 December 2020

Acetylcholine receptor channel imaged in the open state

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12 December 2020

Determination of amino acids critical to the main immunogenic region of intact acetylcholine receptors by in vitro mutagenesis

1 reference

12 December 2020

Native Nicotinic Acetylcholine Receptors in Human Imr32 Neuroblastoma Cells: Functional, Immunological and Pharmacological Properties

1 reference

12 December 2020

Congenital myasthenic syndromes due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene: identification and functional characterization of six new mutations

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12 December 2020

Homomers of alpha 8 and alpha 7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties.

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12 December 2020

Molecular and cellular mechanisms of general anaesthesia

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12 December 2020

Neuronal nicotinic acetylcholine receptors

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12 December 2020

The role of cigarettes and nicotine in the onset and treatment of ulcerative colitis

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12 December 2020

A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes

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12 December 2020

Differential sensitivities of mammalian neuronal and muscle nicotinic acetylcholine receptors to general anesthetics.

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12 December 2020

Evidence for spare nicotinic acetylcholine receptors and a beta 4 subunit in bovine adrenal chromaffin cells: studies using bromoacetylcholine, epibatidine, cytisine and mAb35.

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12 December 2020

Recent advances in defining the neuropathology of schizophrenia

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12 December 2020

d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor

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12 December 2020

End-plate acetylcholine receptor deficiency due to nonsense mutations in the epsilon subunit

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12 December 2020

Identification of a novel amino acid alpha-tyrosine 93 within the cholinergic ligands-binding sites of the acetylcholine receptor by photoaffinity labeling. Additional evidence for a three-loop model of the cholinergic ligands-binding sites

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12 December 2020

Antibodies in sera from patients with myasthenia gravis do not bind to nicotinic acetylcholine receptors from human brain.

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12 December 2020

Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies

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12 December 2020

Nicotine therapy for ulcerative colitis

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12 December 2020

The kinetic properties of neuronal nicotinic receptors: genetic basis of functional diversity

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12 December 2020

Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected.

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12 December 2020

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

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12 December 2020

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

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12 December 2020

Acetylcholine receptor: complex of homologous subunits

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12 December 2020

Divergent tolerance to metabolic and cardiovascular effects of nicotine in smokers with low and high levels of cigarette consumption

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12 December 2020

Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis

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12 December 2020

Mortality from tobacco in developed countries: indirect estimation from national vital statistics.

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12 December 2020

Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity

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12 December 2020

Chronic nicotine and mecamylamine treatment increase brain nicotinic receptor binding without changing alpha 4 or beta 2 mRNA levels

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12 December 2020

Neurons can maintain multiple classes of nicotinic acetylcholine receptors distinguished by different subunit compositions

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12 December 2020

Expression of the nicotinic receptor alpha 7 gene in tendon and periosteum during early development.

1 reference

12 December 2020

(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.

1 reference

12 December 2020

In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418.

1 reference

12 December 2020

Nicotinic receptors that bind α-bungarotoxin on neurons raise intracellular free ca2+

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12 December 2020

alpha-Bungarotoxin-sensitive nicotinic receptors on bovine chromaffin cells: molecular cloning, functional expression and alternative splicing of the alpha 7 subunit.

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12 December 2020

1 reference

12 December 2020

Mechanism of action of ethanol: initial central nervous system actions.

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12 December 2020

Nicotinic receptor function in schizophrenia

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12 December 2020

Nicotine-induced increase in neuronal nicotinic receptors results from a decrease in the rate of receptor turnover.

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12 December 2020

A muscle acetylcholine receptor is expressed in the human cerebellar medulloblastoma cell line TE671.

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12 December 2020

A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

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12 December 2020

Synaptic currents generated by neuronal acetylcholine receptors sensitive to alpha-bungarotoxin

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12 December 2020

Mutation of the acetylcholine receptor alpha subunit causes a slow-channel myasthenic syndrome by enhancing agonist binding affinity

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12 December 2020

Signs and symptoms of tobacco withdrawal.

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12 December 2020

Congenital myasthenic syndrome caused by prolonged acetylcholine receptor channel openings due to a mutation in the M2 domain of the epsilon subunit

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12 December 2020

Activation of alpha7 nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons.

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12 December 2020

The ion channel of the nicotinic acetylcholine receptor is formed by the homologous helices M II of the receptor subunits

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12 December 2020

Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.

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12 December 2020

Hippocampal synaptic transmission enhanced by low concentrations of nicotine.

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12 December 2020

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment

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12 December 2020

Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.

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12 December 2020

Synaptic and extrasynaptic distribution of two distinct populations of nicotinic acetylcholine receptor clusters in the frog cardiac ganglion

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12 December 2020

Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle

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12 December 2020

Mucosal tolerance to experimental autoimmune myasthenia gravis is associated with down-regulation of AChR-specific IFN-gamma-expressing Th1-like cells and up-regulation of TGF-beta mRNA in mononuclear cells

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12 December 2020

Nicotine-induced protection against glutamate cytotoxicity. Nicotinic cholinergic receptor-mediated inhibition of nitric oxide formation.

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12 December 2020

Mutation causing autosomal dominant nocturnal frontal lobe epilepsy alters Ca2+ permeability, conductance, and gating of human alpha4beta2 nicotinic acetylcholine receptors

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12 December 2020

Effects of ethanol on cigarette smoking by volunteers without histories of alcoholism

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12 December 2020

The arrangement of the subunits of the acetylcholine receptor of Torpedo californica

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12 December 2020

Effects of chronic nicotinic ligand exposure on functional activity of nicotinic acetylcholine receptors expressed by cells of the PC12 rat pheochromocytoma or the TE671/RD human clonal line

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12 December 2020

Potent modulation of neuronal nicotinic acetylcholine receptor-channel by ethanol

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12 December 2020

Immunocytochemical localization of the alpha 7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system.

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12 December 2020

The main immunogenic region (MIR) of the nicotinic acetylcholine receptor and the anti-MIR antibodies

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12 December 2020

Presynaptic nicotinic ACh receptors

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12 December 2020

Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment

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12 December 2020

Asymmetric contribution of the conserved disulfide loop to subunit oligomerization and assembly of the nicotinic acetylcholine receptor.

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12 December 2020

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

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12 December 2020

Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.

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12 December 2020

B cell responses to acetylcholine receptor in rats orally tolerized against experimental autoimmune myasthenia gravis

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12 December 2020

Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

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12 December 2020

Synaptic transmission at vertebrate hair cells

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12 December 2020

Smoking cessation and severity of weight gain in a national cohort

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12 December 2020

Supersensitive sites in the central nervous system. Anesthetics block brain nicotinic receptors.

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12 December 2020

Receptor classes and the transmitter-gated ion channels

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12 December 2020

Three-dimensional location of the main immunogenic region of the acetylcholine receptor

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12 December 2020

"Orphan" alpha6 nicotinic AChR subunit can form a functional heteromeric acetylcholine receptor

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12 December 2020

Identification of acetylcholine receptor channel-lining residues in the M1 segment of the alpha-subunit.

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12 December 2020

Three subtypes of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors are expressed in chick retina.

1 reference

12 December 2020

Molecular evolution of the nicotinic acetylcholine receptor: an example of multigene family in excitable cells

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12 December 2020

Neuronal-type nicotinic receptors in human neuroblastoma and small-cell lung carcinoma cell lines

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12 December 2020

Altered muscarinic and nicotinic receptor densities in cortical and subcortical brain regions in Parkinson's disease.

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12 December 2020

Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor.

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12 December 2020

Arthrogryposis multiplex congenita with maternal autoantibodies specific for a fetal antigen

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12 December 2020

Structure of the nicotinic receptor acetylcholine-binding site. Identification of acidic residues in the delta subunit within 0.9 nm of the 5 alpha subunit-binding

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12 December 2020

The diversity of neuronal nicotinic acetylcholine receptors

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12 December 2020

Characterization of d-tubocurarine binding site of Torpedo acetylcholine receptor.

1 reference

12 December 2020

Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the alpha subunit.

1 reference

12 December 2020

New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome

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12 December 2020

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

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12 December 2020

Oral administration of acetylcholine receptor: effects on experimental myasthenia gravis

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12 December 2020

Allosteric transitions of the acetylcholine receptor probed at the amino acid level with a photolabile cholinergic ligand

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12 December 2020

An insertion mutation of the CHRNA4 gene in a family with autosomal dominant nocturnal frontal lobe epilepsy

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12 December 2020

Serotonin release and cell proliferation are under the control of alpha-bungarotoxin-sensitive nicotinic receptors in small-cell lung carcinoma cell lines

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12 December 2020

Pilot trial of nicotine patches as an alternative to corticosteroids in ulcerative colitis

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12 December 2020

Acute thermogenic effects of nicotine and alcohol in healthy male and female smokers.

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12 December 2020

Cholinergic stimulation of human microcytoma cell line H69.

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12 December 2020

Tolerance to and cross tolerance between ethanol and nicotine

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12 December 2020

Excitatory amino acid neurotoxicity and neurodegenerative disease

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12 December 2020

Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo

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12 December 2020

Interactions between a novel cholinergic ion channel agonist, SIB-1765F and L-DOPA in the reserpine model of Parkinson's disease in rats.

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12 December 2020

Chimaeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities.

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12 December 2020

Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine

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12 December 2020

Nicotinic acetylcholine receptor at 9 A resolution.

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12 December 2020

Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

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12 December 2020

Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor

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12 December 2020

Pronounced cellular diversity and extrasynaptic location of nicotinic acetylcholine receptor subunit immunoreactivities in the chicken pretectum

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12 December 2020

Molecular weight in detergent solution of acetylcholine receptor from Torpedo californica

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12 December 2020

Activation of keratinocyte nicotinic cholinergic receptors stimulates calcium influx and enhances cell differentiation.

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12 December 2020

Neuronal-type acetylcholine receptors and regulation of alpha 7 gene expression in vertebrate skeletal muscle

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12 December 2020

Nicotinic receptor stimulation protects neurons against beta-amyloid toxicity.

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12 December 2020

Autoimmunity to the voltage-gated calcium channel underlies the Lambert-Eaton myasthenic syndrome, a paraneoplastic disorder

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12 December 2020

Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes

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12 December 2020

An amino acid exchange in the second transmembrane segment of a neuronal nicotinic receptor causes partial epilepsy by altering its desensitization kinetics

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12 December 2020

Chronic nicotine treatment up-regulates alpha3 and alpha7 acetylcholine receptor subtypes expressed by the human neuroblastoma cell line SH-SY5Y.

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12 December 2020

Acetylcholine receptor binding site contains a disulfide cross-link between adjacent half-cystinyl residues

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12 December 2020

Central cholinergic systems and cognition

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12 December 2020

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

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12 December 2020

The contributions of aspartyl residues in the acetylcholine receptor gamma and delta subunits to the binding of agonists and competitive antagonists

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12 December 2020

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium.

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12 December 2020

Myasthenic syndromes attributed to mutations affecting the epsilon subunit of the acetylcholine receptor

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12 December 2020

Stable expression and pharmacological properties of the human alpha 7 nicotinic acetylcholine receptor

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12 December 2020

Assembly of human neuronal nicotinic receptor alpha5 subunits with alpha3, beta2, and beta4 subunits

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12 December 2020

The effects of nicotine on attention, information processing, and short-term memory in patients with dementia of the Alzheimer type

1 reference

12 December 2020

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding alpha-subunit precursor of muscle acetylcholine receptor

1 reference

12 December 2020

(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization

1 reference

12 December 2020

Common neural substrates for the addictive properties of nicotine and cocaine.

1 reference

12 December 2020

Reductions in acetylcholine and nicotine binding in several degenerative diseases

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12 December 2020

Acetylcholine receptors in human thymic myoid cells in situ: an immunohistological study

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12 December 2020

Pharmacology of nicotine: addiction and therapeutics

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12 December 2020

Functional contributions of alpha5 subunit to neuronal acetylcholine receptor channels.

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12 December 2020

Cigarette smoking and protection from Parkinson's disease: false association or etiologic clue?

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12 December 2020

Effects of a novel cholinergic ion channel agonist SIB-1765F on locomotor activity in rats

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12 December 2020

Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor

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12 December 2020

Nicotinic acetylcholine receptor mRNAs in myasthenic thymuses: association with intrathymic pathogenesis of myasthenia gravis

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12 December 2020

Nicotine for the treatment of Tourette's syndrome

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12 December 2020

Ulcerative colitis responsive to smoking and to nicotine chewing gum in a patient with alpha 1 anti-trypsin deficiency

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12 December 2020

The neurochemistry of Parkinson's disease: effect of L-dopa therapy

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12 December 2020

Ethanol intake increases during continuous administration of amphetamine and nicotine, but not several other drugs

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12 December 2020

Perisynaptic surface distribution of multiple classes of nicotinic acetylcholine receptors on neurons in the chicken ciliary ganglion.

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12 December 2020

Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain

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12 December 2020

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12 December 2020

Nicotinic binding in rat brain: autoradiographic comparison of [3H]acetylcholine, [3H]nicotine, and [125I]-alpha-bungarotoxin.

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12 December 2020

Formation of oligomers containing the beta3 and beta4 subunits of the rat nicotinic receptor

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12 December 2020

Suppression of experimental autoimmune myasthenia gravis by nasal administration of acetylcholine receptor

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12 December 2020

The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine

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12 December 2020

Mechanisms that may underlie the behavioural effects of ethanol

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12 December 2020

Current drug therapy for Parkinson's disease. A review

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12 December 2020

Autosomal dominant nocturnal frontal lobe epilepsy. A distinctive clinical disorder

1 reference

12 December 2020

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

1 reference

12 December 2020

Chronic nicotine exposure differentially affects the function of human alpha3, alpha4, and alpha7 neuronal nicotinic receptor subtypes.

1 reference

12 December 2020

A leucine-to-phenylalanine substitution in the acetylcholine receptor ion channel in a family with the slow-channel syndrome

1 reference

12 December 2020

Newly recognized congenital myasthenic syndrome associated with high conductance and fast closure of the acetylcholine receptor channel.

1 reference

12 December 2020

Combined administration of agonist-antagonist as a method of regulating receptor activation

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12 December 2020

Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function.

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12 December 2020

Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure

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12 December 2020

Sustained nicotine exposure differentially affects alpha 3 beta 2 and alpha 4 beta 2 neuronal nicotinic receptors expressed in Xenopus oocytes.

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12 December 2020

Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons.

1 reference

12 December 2020

Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor

1 reference

12 December 2020

Oral tolerance in myasthenia gravis

1 reference

12 December 2020

Pharmacokinetics of nicotine carbomer enemas: a new treatment modality for ulcerative colitis

1 reference

12 December 2020

Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of residues that determine curare selectivity

1 reference

12 December 2020

Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology

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12 December 2020

Neurotransmitter regulation of neuronal outgrowth, plasticity and survival

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12 December 2020

Expression of alpha-3, alpha-5, and beta-4 neuronal acetylcholine receptor subunit transcripts in normal and myasthenia gravis thymus. Identification of thymocytes expressing the alpha-3 transcripts

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12 December 2020

A beta-subunit mutation in the acetylcholine receptor channel gate causes severe slow-channel syndrome

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12 December 2020

Stable expression, pharmacologic properties and regulation of the human neuronal nicotinic acetylcholine alpha 4 beta 2 receptor

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12 December 2020

Longlasting improvement of Tourette's syndrome with transdermal nicotine

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12 December 2020

Homology and analogy in transmembrane channel design: lessons from synaptic membrane proteins

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12 December 2020

Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist.

1 reference

12 December 2020

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02740634

1 reference

PubMed ID

9396010

Dimensions Publication ID

6 October 2017

0 references

1 reference

PubMed ID

9396010