Caspases induce cytochrome c release from mitochondria by activating cytosolic factors (Q41671448)

6 October 2017

Caspases induce cytochrome c release from mitochondria by activating cytosolic factors (English)

1 reference

6 October 2017

Bossy-Wetzel E

1

1 reference

PubMed ID

10364179

6 October 2017

Green DR

series ordinal

2

1 reference

PubMed ID

10364179

6 October 2017

language of work or name

English

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publication date

1 June 1999

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Journal of Biological Chemistry

6 October 2017

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6 October 2017

274

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6 October 2017

25

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6 October 2017

17484-17490

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Protease activation during apoptosis: death by a thousand cuts?

6 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Human ICE/CED-3 protease nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Caspases: killer proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Caspases: the executioners of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Apoptosis by death factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Autoproteolytic activation of pro-caspases by oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Pro-caspase-3 is a major physiologic target of caspase-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Loss of function of cytochrome c in Jurkat cells undergoing fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Modulation of cell death by Bcl-XL through caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Human IAP-like protein regulates programmed cell death downstream of Bcl-xL and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

BID: a novel BH3 domain-only death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

FLICE Induced Apoptosis in a Cell-free System

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17484

21 January 2018

Identifiers

DOI

10.1074/JBC.274.25.17484

1 reference

6 October 2017

1 reference

PubMed ID

10364179