Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3. (Q41673327)

6 October 2017

Regulation of mitochondrial integrity, autophagy and cell survival by BNIP3. (English)

1 reference

6 October 2017

0 references

Kristin Tracy

1

1 reference

PMCID

2989881

6 October 2017

Kay F Macleod

series ordinal

2

1 reference

PMCID

2989881

6 October 2017

language of work or name

1 reference

15 August 2007

1 reference

6 October 2017

1 reference

6 October 2017

3

1 reference

6 October 2017

6

1 reference

6 October 2017

616-619

1 reference

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Unique dimeric structure of BNip3 transmembrane domain suggests membrane permeabilization as a cell death trigger

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Potential therapeutic applications of autophagy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Autophagy, mitochondrial quality control, and oncogenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Hypoxia-induced energy stress regulates mRNA translation and cell growth

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Bcl-2/adenovirus E1B 19 kDa interacting protein-3 knockdown enables growth of breast cancer metastases in the lung, liver, and bone.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Autophagy: molecular machinery for self-eating

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

The role of autophagy in cancer development and response to therapy.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

HIF-1 and human disease: one highly involved factor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989881

Hypoxia induces the expression of the pro-apoptotic gene BNIP3

12 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17786027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inflammation and necrosis promote tumour growth

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17786027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix-helix interactions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17786027

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/AUTO.4892

1 reference

6 October 2017

1 reference

6 October 2017

1 reference

PMCID

2989881