Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells (Q41690953)

7 October 2017

title

Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells (English)

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7 October 2017

4

Olefsky JM

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7 October 2017

Zapf-Colby A

1

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7 October 2017

Eichhorn J

series ordinal

2

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7 October 2017

Webster NJ

series ordinal

3

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7 October 2017

language of work or name

English

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publication date

1 September 1999

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7 October 2017

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7 October 2017

volume

18

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7 October 2017

issue

35

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7 October 2017

page(s)

4908-4919

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

7 October 2017

cites work

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Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase

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Inositol trisphosphate and diacylglycerol: two interacting second messengers

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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Mitogenic signaling from the egf receptor is attenuated by a phospholipase C-gamma/protein kinase C feedback mechanism

21 January 2018

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The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3.

21 January 2018

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Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

21 January 2018

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PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation

21 January 2018

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Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

21 January 2018

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Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

21 January 2018

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

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A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

21 January 2018

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Novel mechanism of C/EBP beta (NF-M) transcriptional control: activation through derepression.

21 January 2018

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Raf-1 activates MAP kinase-kinase

21 January 2018

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The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

21 January 2018

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

21 January 2018

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Nerve growth factor binds to the 140 kd trk proto-oncogene product and stimulates its association with the src homology domain of phospholipase C gamma 1

21 January 2018

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Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

21 January 2018

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SNT, a Differentiation-Specific Target of Neurotrophic Factor-Induced Tyrosine Kinase Activity in Neurons and PC12 Cells

21 January 2018

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SH2 domains recognize specific phosphopeptide sequences

21 January 2018

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

21 January 2018

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95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site

21 January 2018

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

21 January 2018

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Specific TrkA survival signals interfere with different apoptotic pathways

21 January 2018

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Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene

21 January 2018

1 reference

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Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

21 January 2018

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Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins

21 January 2018

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Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2

21 January 2018

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Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis

21 January 2018

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Stimulation of p21 ras upon T-cell activation

21 January 2018

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Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells

21 January 2018

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Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 January 2018

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Nerve growth factor-induced growth arrest and induction of p21Cip1/WAF1 in NIH-3T3 cells expressing TrkA.

21 January 2018

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7 January 2021

Constitutive overexpression of CDK2 inhibits neuronal differentiation of rat pheochromocytoma PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

Activation of ternary complex factor Elk-1 by MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

Polyproline affinity method for purification of platelet profilin and modification with pyrene-maleimide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

Activity of the MAP kinase ERK2 is controlled by a flexible surface loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202861

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202861

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Dimensions Publication ID

7 October 2017

1030669480

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1 reference