A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine. (Q41701143)

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21 February 2020

title

A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine (English)

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21 February 2020

0 references

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1

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21 February 2020

Lisa A Mielke

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21 February 2020

Kingston H Mills

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21 February 2020

author name string

A C Allen

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21 February 2020

C E Sutton

4

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21 February 2020

R Higgs

5

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21 February 2020

C C Cunningham

6

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21 February 2020

S C Higgins

7

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21 February 2020

publication date

15 October 2014

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21 February 2020

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21 February 2020

volume

8

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21 February 2020

issue

3

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21 February 2020

page(s)

607-617

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The present and future control of pertussis.

21 February 2020

cites work

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Waning protection after fifth dose of acellular pertussis vaccine in children

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Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE responses against pertussis toxin but not against common allergens

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Relative contribution of Th1 and Th17 cells in adaptive immunity to Bordetella pertussis: towards the rational design of an improved acellular pertussis vaccine.

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TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.

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Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology.

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Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: evidence of a role for toxin-induced interleukin-1beta in a new murine model for analysis of neuronal side effects of vaccination

21 January 2018

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Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis

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Differential recognition of structural details of bacterial lipopeptides by toll-like receptors

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Chemical Characterization, Spatial Distribution and Function of a Lipoprotein (Murein-Lipoprotein) of the E. coli Cell Wall. The Specific Effect of Trypsin on the Membrane Structure

21 January 2018

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21 January 2018

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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

21 January 2018

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Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses

21 January 2018

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Conserved nontypeable Haemophilus influenzae-derived TLR2-binding lipopeptides synergize with IFN-beta to increase cytokine production by resident murine and human alveolar macrophages.

21 January 2018

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Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

21 January 2018

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

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IL-17-producing γδ T cells and innate lymphoid cells

21 January 2018

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Protection against Bordetella pertussis in mice in the absence of detectable circulating antibody: implications for long-term immunity in children.

21 January 2018

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Dendritic cells and other innate determinants of T helper cell polarisation.

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Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

21 January 2018

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TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain

21 January 2018

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Antibodies recognizing protective pertussis toxin epitopes are preferentially elicited by natural infection versus acellular immunization

21 January 2018

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Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussi

21 January 2018

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Effective immunization against Bordetella pertussis respiratory infection in mice is dependent on induction of cell-mediated immunity

21 January 2018

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12 December 2020

Pertussis resurgence: waning immunity and pathogen adaptation - two sides of the same coin

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12 December 2020

Vaccine- and antigen-dependent type 1 and type 2 cytokine induction after primary vaccination of infants with whole-cell or acellular pertussis vaccines

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12 December 2020

Covalent lipoprotein from the outer membrane of Escherichia coli

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12 December 2020