vitamin D receptor (Q417057)

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mammalian protein found in Homo sapiens
  • vitamin D nuclear receptor variant 1
  • protein phosphatase 1, regulatory subunit 163
  • 1,25-dihydroxyvitamin D3 receptor
  • vitamin D (1,25- dihydroxyvitamin D3) receptor
  • VDR
  • Calcitriol Receptor
  • vitamin D3 receptor
  • Calcitriol Receptors
  • nuclear receptor subfamily 1 group I member 1
  • Receptors, Calcitriol
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Language Label Description Also known as
English
vitamin D receptor
mammalian protein found in Homo sapiens
  • vitamin D nuclear receptor variant 1
  • protein phosphatase 1, regulatory subunit 163
  • 1,25-dihydroxyvitamin D3 receptor
  • vitamin D (1,25- dihydroxyvitamin D3) receptor
  • VDR
  • Calcitriol Receptor
  • vitamin D3 receptor
  • Calcitriol Receptors
  • nuclear receptor subfamily 1 group I member 1
  • Receptors, Calcitriol

Statements

molecular function
protein binding
determination method
IPI
18 references
retrieved
8 April 2019
stated in
Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Modulation of the vitamin D3 response by cancer-associated mutant p53
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Structure of the full human RXR/VDR nuclear receptor heterodimer complex with its DR3 target DNA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
retrieved
8 April 2019
stated in
Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IPI
nuclear receptor activity
determination method
IDA
IEA
IMP
6 references
retrieved
8 April 2019
stated in
Functional analyses of a novel missense and other mutations of the vitamin D receptor in association with alopecia.
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IEA
retrieved
8 April 2019
stated in
Regulation of human epidermal keratinocyte differentiation by the vitamin D receptor and its coactivators DRIP205, SRC2, and SRC3
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IDA
retrieved
8 April 2019
stated in
Vitamin D receptor as an intestinal bile acid sensor
GOA
curator
UniProt
UniProt protein ID
P11473
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IDA
retrieved
8 April 2019
stated in
Human mammary epithelial cells express CYP27B1 and are growth inhibited by 25-hydroxyvitamin D-3, the major circulating form of vitamin D-3
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11473
determination method
IDA
cell component
biological process
Gene Atlas image
PBB GE VDR 204254 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D018167
subject named as
Receptors, Calcitriol
0 references
PDB structure ID
4FHI
1 reference
stated in
UniProt
UniProt protein ID
Q9PTN2
retrieved
8 September 2023
2HBH
1 reference
stated in
UniProt
UniProt protein ID
Q9PTN2
retrieved
8 September 2023
 
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