Immunologic approaches to inhibiting cell-surface-residing oncoproteins in human tumors (Q41710798)

7 October 2017

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title

Immunologic approaches to inhibiting cell-surface-residing oncoproteins in human tumors (English)

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7 October 2017

O'Rourke DM

1

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PubMed ID

9479580

7 October 2017

Greene MI

series ordinal

2

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7 October 2017

1 January 1998

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7 October 2017

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7 October 2017

17

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7 October 2017

1-2

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7 October 2017

179-189

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https://scigraph.springernature.com/pub.10.1007/bf02786443

7 October 2017

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cites work

p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1007%2FBF02786443

Tissue-specific transformation by oncogenic mutants of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786443

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786443

A deletion mutation within the ligand binding domain is responsible for activation of epidermal growth factor receptor gene in human brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786443

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

21 January 2018

1 reference

12 December 2020

Breast and ovarian cancer-specific cytotoxic T lymphocytes recognize the same HER2/neu-derived peptide

1 reference

12 December 2020

Synergistic interaction of p185c-neu and the EGF receptor leads to transformation of rodent fibroblasts

1 reference

12 December 2020

Anti-receptor antibodies reverse the phenotype of cells transformed by two interacting proto-oncogene encoded receptor proteins

1 reference

12 December 2020

Monoclonal antibodies identify a cell-surface antigen associated with an activated cellular oncogene

1 reference

12 December 2020

Neu differentiation factor (Heregulin) activates a p53-dependent pathway in cancer cells

1 reference

12 December 2020

Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.

1 reference

12 December 2020

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

12 December 2020

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

1 reference

12 December 2020

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

12 December 2020

Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies

1 reference

12 December 2020

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

12 December 2020

Signal transduction by receptors with tyrosine kinase activity

1 reference

12 December 2020

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

1 reference

12 December 2020

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

12 December 2020

Transformational and altered signal transduction by a naturally occurring mutant EGF receptor

1 reference

12 December 2020

Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

1 reference

12 December 2020

Ligand-induced transformation by a noninternalizing epidermal growth factor receptor

1 reference

12 December 2020

Prevention of breast tumour development in vivo by downregulation of the p185neureceptor

1 reference

12 December 2020

p185c-neu and epidermal growth factor receptor associate into a structure composed of activated kinases

1 reference

12 December 2020

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

1 reference

12 December 2020

Prognostic variables in invasive breast cancer: contribution of comedo versus noncomedo in situ component

1 reference

12 December 2020

The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

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12 December 2020

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors

1 reference

12 December 2020

Dimerization of cell surface receptors in signal transduction

1 reference

12 December 2020

Human breast cancer: prognostic significance of the c-erbB-2 oncoprotein compared with epidermal growth factor receptor, DNA ploidy, and conventional pathologic features

1 reference

12 December 2020

Ligand and p185c-neu density govern receptor interactions and tyrosine kinase activation

1 reference

12 December 2020

The neu (c-erbB-2) oncogene

1 reference

12 December 2020

ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer

1 reference

12 December 2020

A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling

1 reference

12 December 2020

Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen

1 reference

12 December 2020

Interaction of the neu/p185 and EGF receptor tyrosine kinases: implications for cellular transformation and tumor therapy

1 reference

12 December 2020

Monoclonal antibodies specific for the neu oncogene product directly mediate anti-tumor effects in vivo

1 reference

12 December 2020

Expression of c-erbB-2 in Human Pancreatic Adenocarcinomas

1 reference

12 December 2020

Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3

1 reference

12 December 2020

Correlations between intrinsic chemoresistance and HER-2/neu gene expression, p53 gene mutations, and cell proliferation characteristics in non-small cell lung cancer cell lines

1 reference

12 December 2020

Increased natural killer cell activity correlates with low or negative expression of the HER-2/neu oncogene in patients with breast cancer

1 reference

12 December 2020

A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell lines

1 reference

12 December 2020

Analysis of mammalian fibroblast transformation by normal and mutated human EGF receptors

1 reference

12 December 2020

Expression of c-erbB-2 oncoprotein: a prognostic indicator in human breast cancer

1 reference

12 December 2020

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

1 reference

12 December 2020

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

1 reference

12 December 2020

Helplessness as a strategy for avoiding antiglobulin responses to therapeutic monoclonal antibodies

1 reference

12 December 2020

Humanization of an anti-p185HER2 antibody for human cancer therapy

1 reference

12 December 2020

Demonstration by two-color flow cytometry that tyrosine kinase activity is required for down-modulation of the oncogenic neu receptor

1 reference

12 December 2020

Diagnostic utility of oncogenes and their products in human cancer

1 reference

12 December 2020

Expression pattern of the neu (NGL) gene-encoded growth factor receptor protein (p185neu) in normal and transformed epithelial tissues of the digestive tract

1 reference

12 December 2020

A naturally occurring mutant human epidermal growth factor receptor as a target for peptide vaccine immunotherapy of tumors

1 reference

12 December 2020

neu(c-erbB-2/HER2) and the epidermal growth factor receptor (EGFR) in breast cancer

1 reference

12 December 2020

Heterodimerization of c-erbB2 with different epidermal growth factor receptor mutants elicits stimulatory or inhibitory responses

1 reference

12 December 2020

Immunohistochemical evaluation of c-erbB-2 oncogene expression in ductal carcinoma in situ and atypical ductal hyperplasia of the breast

1 reference

12 December 2020

Cell cycle-dependent regulation of p185neu: a relationship between disruption of this regulation and transformation

1 reference

12 December 2020

Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas

1 reference

12 December 2020

Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells

1 reference

12 December 2020

Tumor-specific anti-epidermal growth factor receptor variant III monoclonal antibodies: use of the tyramine-cellobiose radioiodination method enhances cellular retention and uptake in tumor xenografts.

1 reference

12 December 2020

ERBB2 amplification in breast cancer with a high rate of proliferation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02786443

1 reference

PubMed ID

9479580

Dimensions Publication ID

7 October 2017

0 references

1 reference

PubMed ID

9479580