Rapid development of broadly influenza neutralizing antibodies through redundant mutations (Q41710834)

7 October 2017

Rapid development of broadly influenza neutralizing antibodies through redundant mutations (English)

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7 October 2017

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11

Federica Sallusto

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Antonio Lanzavecchia

15

Antonio Lanzavecchia

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7 October 2017

Filippo Turrini

5

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Elisa Vicenzi

Elisa Vicenzi

13

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Gloria Agatic

8

Gloria Agatic

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7 October 2017

2

Mathilde Foglierini

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Blanca Fernandez-Rodriguez

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7

Blanca Fernandez-Rodriguez

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7 October 2017

1

Leontios Pappas

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7 October 2017

Luca Piccoli

3

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7 October 2017

Nicole L Kallewaard

4

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7 October 2017

Chiara Silacci

6

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7 October 2017

Isabella Giacchetto-Sasselli

9

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7 October 2017

Gabriele Pellicciotta

10

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7 October 2017

Qing Zhu

12

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7 October 2017

Davide Corti

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7 October 2017

language of work or name

English

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publication date

5 October 2014

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7 October 2017

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7 October 2017

516

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7 October 2017

7531

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7 October 2017

418-422

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https://scigraph.springernature.com/pub.10.1038/nature13764

7 October 2017

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Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

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Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

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Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

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Structural and genetic basis for development of broadly neutralizing influenza antibodies

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Polymorphism in the immunoglobulin VH gene V1-69 affects susceptibility to rheumatoid arthritis in subjects lacking the HLA-DRB1 shared epitope

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

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Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

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Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate

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Different B cell populations mediate early and late memory during an endogenous immune response

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Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus

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A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies

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Identification of TRIM22 single nucleotide polymorphisms associated with loss of inhibition of HIV-1 transcription and advanced HIV-1 disease

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An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus.

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21 January 2018

Identifiers

DOI

10.1038/NATURE13764

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Dimensions Publication ID

7 October 2017

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