The urokinase plasminogen activator receptor (UPAR) is preferentially induced by nerve growth factor in PC12 pheochromocytoma cells and is required for NGF-driven differentiation. (Q41713149)

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scientific article published on January 2000

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English	The urokinase plasminogen activator receptor (UPAR) is preferentially induced by nerve growth factor in PC12 pheochromocytoma cells and is required for NGF-driven differentiation.	scientific article published on January 2000

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scholarly article

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Europe PubMed Central

7 October 2017

The urokinase plasminogen activator receptor (UPAR) is preferentially induced by nerve growth factor in PC12 pheochromocytoma cells and is required for NGF-driven differentiation (English)

1 reference

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12 May 2020

phaeochromocytoma

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inferred from title

Shafaat Rabbani

5

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12 May 2020

author name string

R Farias-Eisner

1

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12 May 2020

L Vician

2

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12 May 2020

A Silver

3

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12 May 2020

S Reddy

4

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12 May 2020

H R Herschman

6

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12 May 2020

language of work or name

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publication date

1 January 2000

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Journal of Neuroscience

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12 May 2020

20

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1

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12 May 2020

230-239

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12 May 2020

TIS gene expression in cultured rat astrocytes: multiple pathways of induction by mitogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor

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https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

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The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule

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https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

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NGF induces transient but not sustained activation of ERK in PC12 mutant cells incapable of differentiating

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https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

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NGF induction of the gene encoding the protease transin accompanies neuronal differentiation in PC12 cells

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https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-1 behaves as a delayed response gene in PC12 cells differentiated by nerve growth factor

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https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

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Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of neurite outgrowth by interleukin-6 is accompanied by activation of Stat3 signaling pathway in a variant PC12 cell (E2) line

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning the differences between two complex genomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C-epsilon plays a role in neurite outgrowth in response to epidermal growth factor and nerve growth factor in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function of the urokinase receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human urokinase-type plasminogen activator primes neutrophils for superoxide anion release. Possible roles of complement receptor type 3 and calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel nerve growth factor-responsive element in the stromelysin-1 (transin) gene that is necessary and sufficient for gene expression in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin receptors: a window into neuronal differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin regulation of gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel, nerve growth factor-activated pathway involving nitric oxide, p53, and p21WAF1 regulates neuronal differentiation of PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase receptor is required for human monocyte chemotaxis in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early responses of PC-12 cells to NGF and EGF: effect of K252a and 5'-methylthioadenosine on gene expression and membrane protein methylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase receptor is associated with the components of the JAK1/STAT1 signaling pathway and leads to activation of this pathway upon receptor clustering in the human kidney epithelial tumor cell line TCL-598

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metalloproteases and urokinase in angiogenesis and tumor progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of integrin function by the urokinase receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of multiple isoforms of the rat urokinase receptor in osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mixed backbone oligonucleotides: improvement in oligonucleotide-induced toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the human urokinase receptor gene and its similarity to CD59 and the Ly-6 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Application of a rapid method (targeted display) for the identification of differentially expressed mRNAs following NGF-induced neuronal differentiation in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serine 133-phosphorylated CREB induces transcription via a cooperative mechanism that may confer specificity to neurotrophin signals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation and characterization of urokinase receptor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Re-examination of the local control by nerve growth factor of the outgrowth of neurites in PC12D cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single pulse of nerve growth factor triggers long-term neuronal excitability through sodium channel gene induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary response genes induced by growth factors and tumor promoters

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-mediated endocytosis of urokinase-type plasminogen activator is regulated by cAMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide triggers a switch to growth arrest during differentiation of neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seizure activity induces PIM-1 expression in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protein induced by NGF in PC12 cells is stored in secretory vesicles and released through the regulated pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KID-1, a protein kinase induced by depolarization in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB: a major mediator of neuronal neurotrophin responses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the plasminogen activator/plasmin system in rat liver regenerating by recruitment of oval cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of urokinase-type plasminogen activator with its receptor rapidly induces activation of glucose transporters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor induces transcription of NGFIA through complex regulatory elements that are also sensitive to serum and phorbol 12-myristate 13-acetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF in combination with depolarization or cAMP produces morphological but not physiological differentiation in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis and cytoskeleton reorganization in rat smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of genes preferentially induced by nerve growth factor versus epidermal growth factor in PC12 pheochromocytoma cells by means of representational difference analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulated expression of plasminogen activator system components in cultured cells from dissociated mouse dorsal root ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic local alignment search tool

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10627600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.20-01-00230.2000

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6774117&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6774117&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6774117&resulttype=core&format=json

12 May 2020

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